Science topic

3D - Science topic

Explore the latest questions and answers in 3D, and find 3D experts.
Questions related to 3D
  • asked a question related to 3D
Question
2 answers
I wanted to know how will I be able to visualise hydrophobicity and electrostatic potential of proteins from the 3D structure and colour them?
Relevant answer
Answer
I want to just add to Rob Keller's comment:
Chimera is a free tool that can show hydrophobic/hydrophilic surfaces with a few clicks instead of using a script for PyMOL.
Open Chimera, load your protein, go to Presets, then click "Interactive 3 (hydrophobicity, surface)".
Thats it.
  • asked a question related to 3D
Question
3 answers
The reason why sporozoites of the five species of malarial parasite can infect hepatocytes is because the gene expressions patterns in hepatocytes are suitable for sporozoite infections. Therefore, alteration of gene expression patterns in hepatocytes will reduce the susceptibility to sporozoite infections. Perturbation of 3D genome architecture could change gene expression patterns. Many research results have shown that X-ray irradiation can change 3D genome architecture, leading to alteration of gene expression patterns. We assume that a low-dose X-ray irradiation of the whole liver might protect people from malaria infections for a long time (hopefully, more than one year). Therefore, X-ray irradiation could be a non-antigen-based “vaccine” to prevent all malaria infections. Certainly, this theory needs experimental and clinical trials to prove.
Relevant answer
Answer
X-ray irradiation of the liver might prevent malaria infections, but there is no reason to treat malaria infection with X-ray irradiation of the liver.
  • asked a question related to 3D
Question
5 answers
If a 3D protein is obtained with the inhibitor complex, its wild-type size may change completely. In this case, it seems correct to investigate the binding mode with the inhibitor molecule. If the protein to be investigated has only an inhibitor complex, what protein should I select in the PDB and in my activator molecule research, and what path should it follow?
Relevant answer
Answer
Nail Besli Yes you are absolutely correct about the change in conformation of the protein when bound to two different molecule types. However, if you have no structural information available for the conformation with the activator, but have the information for the inhibitor binding.
Molecular dynamics can be a good way to gain some insights of how these conformations change when your protein is unbound (WT), bound to inhibitor and bound to the activator.
This comparative analysis of the structural transitions on a free energy landscape may provide you with detailed conformational transitions that are playing roles. It might be external factors too like salt concentration, pH temperature and so on.
Further, you may use this information to validate your results experimentally and if the changes are adequate you can measure them using fluorescence spectroscopy and circular dichroism spectroscopy experiments.
  • asked a question related to 3D
Question
4 answers
2024 6th International Conference on Electronic Engineering and Informatics (EEI 2024) will be held in Chongqing, China from June 28 to June 30, 2024.
Conference Website: https://ais.cn/u/2qEVvu
EEI 2024 is to bring together innovative academics and industrial experts in the field of Electronic Engineering and Informatics to a common forum. The primary goal of the conference is to promote research and developmental activities in Electronic Engineering and Informatics, and another goal is to promote scientific information interchange between researchers, developers, engineers, students, and practitioners working all around the world. The conference will be held every year to make it an ideal platform for people to share views and experiences in  Electronic Engineering and Informatics and related areas.
We warmly invite you to participate in EEI 2024 and look forward to seeing you in Chongqing!
---Call For Papers---
The topics of interest for submission include, but are not limited to:
◕ Electronic Technology
- 3D process and integration technology
- Substrate embedding and advanced flip chip packaging
- MEMS and sensor technology
- Design and Analysis of Transmission System
- New materials, equipment and 3D interconnection
- Wearable, flexible and stretchable electronics
- Optical interconnection and 3D photonics
- Digital system and logic design
- Computer architecture and VLSI
- Network-driven multi-core chip
- Advanced robotic system
- Analog and digital electronics
- Signals and Systems
◕Information and Communication
- Electronic equipment
- Satellite and Space Communications
- Network and Information Security
- Signal processing for wireless communication
- Cognitive Radio and Software Radio
- Optical networks and systems
- Electromagnetic field theory
- Antenna, propagation and transmission technology
- Optical communication
- Radar signal and data processing
- Other related topics
All accepted full papers will be published in the conference proceedings and will be submitted to EI Compendex / Scopus for indexing.
Important Dates:
Full Paper Submission Date: April 10, 2024
Registration Deadline: June 17, 2024
Final Paper Submission Date: May 25, 2024
Conference Dates: June 28-30, 2024
For More Details please visit:
Invitation code: AISCONF
*Using the invitation code on submission system/registration can get priority review and feedback
Relevant answer
Answer
Dear Bouziane Ghoual ,Thank you for your attention to EEI 2024. We apologize that considering the on-site experience, this conference only accepts offline presentation in China.
If you are interested in this conference, you could consider submitting your papers and attending the conference offline. Or you could also consider joining as a listener without submmison online.(Listener could participate online)
  • asked a question related to 3D
Question
17 answers
I am a researcher and I have to model a tunnel in 3D. I would like to know the better software to perform it. Whether it is Plaxis 3D or MIDAS GTS NX or any other suggestions please?
Relevant answer
Answer
hello..you can download and install even the standard PLAXIS software..you go to PLAXIS main website(www.plaxis.in)..try to find out one month free download versions for students and faculties from any university..like thse many other softwars like ABAQUS, ANSYS..you have to find out from their main web site..ok all the best pa..
  • asked a question related to 3D
Question
1 answer
In CFD simulations, determining the appropriate inlet and outlet boundary conditions is crucial for accurately modeling recirculation phenomena in both two-dimensional (2D) and three-dimensional (3D) scenarios.
For recirculation simulations, the inlet boundary condition typically involves prescribing the flow properties entering the domain. This may include specifying the velocity profile, temperature, turbulence characteristics, and any other relevant parameters. In 2D simulations, the inlet boundary condition can be defined as a 2D plane through which fluid enters the computational domain. In 3D simulations, this boundary condition extends to a full 3D volume or surface. In both 2D and 3D simulations, accurately representing the inlet and outlet boundary conditions is critical for capturing the complex flow dynamics associated with recirculation zones. Properly defined boundary conditions ensure that the simulated flow field closely matches the real-world behavior, thus enhancing the reliability and accuracy of the CFD predictions.
Relevant answer
Answer
That is not exactly right, the combination of inflow/outflow BCs depends on the assumption of the flow, compressible or incompressible. In case of compressble flows you have further to distinguish between subsonic or supersonic conditions.
  • asked a question related to 3D
Question
1 answer
These cells are cultured on 4mg/ml collagen surface in a 3D luminal channel (within collagen). I need to change media every day. The cell sheet covering the surface of the channel retracts upon the media change, but regrows again to cover the full surface again.
Relevant answer
Answer
The flow from the pipette must be very high during the media replenishment - resulting in detachment of the cells. Try using reservoirs or syringe pump at very low flow rate to replenish the media for cell growth and maintenance.
  • asked a question related to 3D
Question
10 answers
Hello everyone
I have some problems to analysis the xrd results to get the corresponding 3D structure of my protein with x'pert high score plus.
Does enyone have valuable suggestions?
Thanks
Relevant answer
Answer
Of course
  • asked a question related to 3D
Question
3 answers
Many physicists and mathematicians assume that mother nature has two distinct languages, one for macroscopic objects in classical physics and the second for microscopic subatomic objects which is Schrödinger's PDE and its derivatives.
Moreover, the old iron guards of SE believe that these two languages ​​​​reduce to a single one which is the solution of SE, assuming that eventually it can deal with macroscopic objects (Via SE has no scales and principle of Correspondence).
The question is valid:
Does it make sense for a macroscopic quantity (time) to appear in a microscopic equation (SE) unless SE itself is a statistical equation?
Conversely, we assume that nature has only one language to speak to itself, namely the physical B-matrix statistical chains capable of solving the classical heat diffusion equation and Schrodinger's quantum PDE in a 3D configuration space.
Strikingly, the closed, empty 3D box has its own statistics, even without any energy density fields inside.
A striking example of the above statement appears in limited mathematical integrations:
I= ∫ y dx from x=a to x=b,
I=∫∫ W(x,y) dx dy from x=a to x=b and y=b to y=c.
..etc..
while they can be calculated precisely thanks to the transition chains of the matrix B[1].
1-Effective unconventional approach to statistical differentiation and statistical integration
November 2022
Relevant answer
Answer
This short answer is simply to clarify to our colleague Professor Murteza the question and his answer and to thank him for his helpful suggestions:
1-We admit that the answer above is not clear enough and requires some logical and mathematical clarification.
2-We believe that your request also requires additional clarification.
Please write your answer/question in sheet music form, i.e.:
1-What is the origin of.,.
2-Why is this term...
3-How to derive/apply...
etc..
And we will do our best to respond as soon as we receive your inquiries.
  • asked a question related to 3D
Question
1 answer
I would like to cultivate lactobacilli in an intestinal organ-on-chip model and stain it with a suitable dye either beforehand or, if necessary, after the end of the experiment with a suitable antibody for immunofluorescence microscopy.
Briefly, I would like to check the Lactobacillus attachment/localization to/in the intestinal tissue.
Is there anyone with experience in this area and could explain possible procedures?
Thank you very much in advance!
Relevant answer
Answer
May consider using Permai fluorescence dye.
  • asked a question related to 3D
Question
2 answers
Dear colleagues,
I want to study the case of flapping wing 3D by using CFD-Fluent. I defined the X and Z angular velocities by UDF, where Omega[0]=phi0*2*3.14*f*sin(2*3.14*f*time) and Omega[2]=teta0*2*3.14*f*cos(2*3.14*f*time).
But after simulation I finde that the wing rotates around Y axis over it's ossilations around X and Z axises inspite omega[1] is not defined in UDF.
Can you help me please!
this is the UDF code :
#include "udf.h"
/* this function defines velocity of center of gravity for 3D flapping motion*/
DEFINE_CG_MOTION(Flapping, dt, vel, omega, time, dtime)
{
Thread *t;
face_t *f;
/*reset velocities */
NV_S(vel,=,0.0);
NV_S(omega,=,0.0);
if (!Data_Valid_P())
return;
/* Get the thread pointer for which this motion is defined */
/* t=DT_THREAD(dt); */
/* Om[1] is the vertical plunging velocity */
/* These velocities below is for phi0=45, teta0=30° and f=5Hz */
omega[0] = 45*3.14/180*2*3.14*5*sin(2*3.14*5*time);
omega[2]=30*3.14/180*2*3.14*5*cos(2*3.14*5*time);
}
Relevant answer
Answer
hi,
Have you been able to figure out the answer, I am currently doing the same thing and I have the same issue.
  • asked a question related to 3D
Question
1 answer
I've already configured my inet to run OSG 3D, but it didn't show me my 3D simulation, it shows me 2D instead.
Relevant answer
Answer
That's not a research question. Look on Stackoverflow, ChatGPT or specialized forum about OMNet++.
  • asked a question related to 3D
Question
1 answer
Hello ResearchGate Community,
I am currently working on my final year undergraduate project, which involves the compression testing of tissue scaffolds, specifically focusing on neural and bone tissues. Due to limitations with 3D bioprinting, I am unable to fabricate actual tissue scaffolds and am thus seeking alternative materials that closely mimic the mechanical properties of these tissues for testing purposes.
Project Overview:
My project aims to analyze the compression resistance and mechanical behavior of tissue scaffolds, with a particular focus on neural and bone tissues. The main challenge I'm facing is identifying suitable substitute materials that can be fabricated (preferably using accessible methods) and used for compression testing to simulate the real mechanical properties of these tissues.
Questions:
1. Material Suggestions: Could anyone recommend materials that have been successfully used to mimic the mechanical properties (such as elasticity, compressive strength, etc.) of neural and bone tissues in compression tests?
2. Fabrication Techniques: Are there specific fabrication techniques (aside from 3D bioprinting) that you have found effective in creating these surrogate materials with properties that are comparable to the actual tissues?
3. Testing Protocols: I would also appreciate any insights or references to standard testing protocols for conducting compression tests on these materials to ensure the results are as reflective as possible of how the actual tissues would behave under similar conditions.
Additional Context:
I am conducting this project as part of an exchange semester in Australia and face the challenge of working independently with limited direct guidance. Thus, any advice, especially from those who have navigated similar projects or have expertise in biomaterials and tissue engineering, would be immensely helpful.
Thank you in advance for your time and assistance. Your insights will not only aid in advancing my project but also contribute significantly to my learning experience in this fascinating area of research.
Best regards,
Anupama
  • asked a question related to 3D
Question
3 answers
Dear All,
I downloaded ZINC000000001115 (Leukeran) in SDF 3D structure from Pubchem, https://pubchem.ncbi.nlm.nih.gov/compound/2708#section=3D-Conformer (figure 1).
Then I converted the ZINC000000001115.sdf into bdbqt files, with the use of Openbabel and AutodockTools, then I got the ZINC000000001115.pdbqt and checked its structure with Discovery Studio 2020 (figure 2). However, ZINC000000001115.pdbqt looks like a broken structure. Is the ZINC000000001115.pdbqt file good for further molecular docking or there is a problem during conversion?
Looking forward to your opinions and solutions.
Thank you and best wishes,
Xiaohua
Relevant answer
Answer
Yeah, I have applied this method then suggested to you.
  • asked a question related to 3D
Question
1 answer
Hey,
I'm pretty new to 3D kinematic analysis in sports, and I'm trying to follow this "protocol", i.e. the exact structure of results as in this article: https://peerj.com/articles/10841/
However, I think I understand how they are calculating the angles at key events and ROM, but I'm not sure how they are calculating the "angular changing rate".
As a data, I have a time series of angular velocity and acceleration. But how do you get just "one number" from time series? Is it also at key events, or can I calculate the "angular changing rate" leading to having just one number from a time series?
Thanks!
Relevant answer
Answer
Hi. If a = 20 deg. b = 50 deg.
When the time at a is 0 s, b is 0.2 s. So, the event from a to b are 0.2 seconds And the anguler change rate that is (50-20)/50, the unit is %. So, the ROM is 50-20, unit is deg.
Best regard
  • asked a question related to 3D
Question
2 answers
After using the command:
gmx sham -f PCAplot2d.xvg -notime -ls gibbs1-2.xpm
(where PCAplot2d.xvg is the PCA plot generated with the gmx anaeig command)
I get the matrix file in a 2D plot, which can be improved by transforming it into an *eps file, using the command:
gmx xpm2ps -f gibbs1-2.xpm -o plot.eps -rainbow blue
How can I obtain 3D free energy landscape after this ?
Relevant answer
Answer
Hey! There's a new package that you can install using "pip install free-energy-landscape", and with this package, you can extract all frames, their CVs (collective variables), and energy based on a threshold value. For example, in the command below, from the inputs corresponding to collective variables 1 and 2, obtain all frames that have an energy value <= 5 KJ/mol:
$ free_energy_landscape collective_variable1.txt collective_variable2.txt --energy 5
  • asked a question related to 3D
Question
2 answers
I wanted to convert few 2D compounds to 3D using Avogadro and then use them for docking. Are these ligands efficient for docking? Will I get accurate results. Thank you in advance.
Relevant answer
Answer
Prasenjit Bhowmik Thank you soo much. I'll look into both the softwares.
  • asked a question related to 3D
Question
1 answer
How to apply shear force of a 3D block .can anyone provide Lammps input script on the application of shear force between two different fixed layer of a block?
Relevant answer
Answer
Relateive keyword is deform in LAMMPS which can shear 3D block for your first question.
Shear force between two different fixed layer of a block can be realized by fix move keyword applied for the upper block. The five move keyword will force the upper block to move regardless of its force on it.
Or you can shear the upper block by ATOMSK or PYTHON code.
  • asked a question related to 3D
Question
1 answer
Is it changed it 3D structure and damage the structure or not?
Relevant answer
Answer
Maryam Ansari Sigmacote, primarily used for rendering surfaces hydrophobic, is a silicone-based solution. In the context of auto-cleaving, we are essentially discussing whether Sigmacote can undergo a self-induced breakdown or alteration. From my experience and understanding, Sigmacote itself is not designed to auto-cleave. It is formulated to create a stable, inert, hydrophobic coating. This stability is a key characteristic, especially in laboratory settings where it's used to prevent the adhesion of aqueous solutions to glassware.
However, if we consider the impact of external factors, the story gets a bit more complex. For example, exposure to certain chemicals, extreme pH conditions, or high temperatures might lead to a breakdown or alteration of the Sigmacote layer. Such conditions could potentially change its 3D structure. This change might not be a cleavage in the strict scientific sense but rather a degradation or breakdown of the silicone polymer chains.
In terms of damaging the structure, it largely depends on what we mean by 'damage'. If the integrity of the hydrophobic layer is compromised, then in a sense, yes, the structure is damaged as it can no longer effectively repel water. This could have implications in experiments where the hydrophobicity of the surface is critical.
In summary, while Sigmacote is not designed to auto-cleave, under certain extreme conditions, its structure can be compromised. It's a reminder of the delicate balance we maintain in scientific experimentation, where each component plays a crucial role and understanding their limitations is as important as understanding their capabilities.
  • asked a question related to 3D
Question
3 answers
Causality means that an effect cannot occur from a cause that is not within the back (past) light cone of that event.
We assume that quantum mechanics respects causality.
However, some physicists and mathematicians claim that in some SE solutions the effect may precede the cause, which nature disapproves of.
This can only be one way to solve the SE, while it's easier to go back and look for a solution.
This is exactly what happens even when solving the 1D, 2D and 3D Schrödinger equation via B-matrix statistical chains, while it is better to first assume the potential landscape before solve.
We recall here the revolutionary discovery of the Planck constant h.
The great Max Planck knew in advance the experimental value of h and went backwards from the erroneous formulas of Wiens and Rayleigh to his exact law of Planck's radiation.
Relevant answer
Answer
I admire the discussion. Yet, I think that there is another important question which contibututes to the entire picture: how to discriminate between causality and randomness? More precisely, the question is twofold: (i) how to discriminate between causal correlataions and provisional ones. (ii) whether and how the same process gives rise to both causal and random-like events?! In this line I still wonder how and why the fluctuations of any matter are specific to that matter regardless to the fact that all current theories of randomness do not prescribe any specificity. As an example my question is why the fluctuations of water are water?!
  • asked a question related to 3D
Question
3 answers
Dear colleagues,
It is known that spatial geometry theorems (e.g.: three perpendiculars theorem, the distance between two straight lines in space, etc,) have been set in dynamic geometric environments to teach in the classroom. But, it is also necessary to remember that there are no classrooms with the possibility to use dynamic geometry tools. For this reason, could you suggest to me papers or books about teaching spatial geometry notions and theorems without software (or, a "board and chalk" approach), please?
Kind regards,
Luis
Relevant answer
Answer
The use of S/W and computer visualization is a very recent turn of events. Mathematics has been developed and taught for centuries prior to the advent of computer visualization tools. Computer visualization is not a necessary condition for the development of geometric intuition. While i don't have any specific title in mind, I suspect text book from the around the mid 20th century would be a good place to start looking.
  • asked a question related to 3D
Question
10 answers
Hello all,
I am trying to find the OSI for the time varying WSS at a point in 3D geometry using COMSOL.
I used all possible methods but failed
If anyone knows, please do share with me.
Relevant answer
Answer
@Hiwa aryan
Sir I'm in a trouble of calculating osi using comsol.
Will you please explain detail how to write the expression?
Actually I can't calculate the average wss.
  • asked a question related to 3D
Question
2 answers
As 3-dimensional transistors based on 1D and 2D materials, can it based on 3D materials?
Relevant answer
Answer
I apologize for any confusion caused by my previous response. To clarify, when discussing transistors based on 3D materials, it refers to transistors built using materials with a three-dimensional crystal structure, as opposed to 1D or 2D materials.
The term "3D materials" can be somewhat ambiguous, as it can refer to materials with a bulk, three-dimensional structure like silicon, or to materials with a more exotic crystal structure such as perovskites or metal-organic frameworks (MOFs). In the context of transistors, the most commonly used semiconductor material is silicon, which has a 3D crystal structure.
  • asked a question related to 3D
Question
2 answers
Hi,
i am currently doing a project where i used a bare soil slope model and rainfall simulation in the lab. all the slope eroded after the experiment. after that, i also tried to simulate the same model in plaxis 3D. i used the same data collected from the actual experiment. my issue is, after the rainfall simulation, the factor of safety increasing highly (5.9) whereas before rainfal it was (3.4). i have tried tweaking with stiffness, unit weights, cohesion but still the fos is coming higher after the rainfall than before. can anyone tell me why the fos coming very high? and, another issue is the pwp from the simulation is coming way higher than the data collected from actual experiment. can anyone help me with these issues? thank you.
Relevant answer
Answer
Plaxis is not the tool to model failure through erosion. The FoS calculation you are describing is a mathematical abstraction to model other mechanisms.
  • asked a question related to 3D
Question
3 answers
Good day,
I investigate the 3D FDTD and TMM simulations in terms of the grating waveguide.
I'm currently setting up the simulation environment and verifying the similarity between the 3D FDTD simulations and TMM using the textbook, the 'L. Chrostowski and M. E. Hochberg, Silicon photonics design. Cambridge University Press, 2015.'
Utilizing the script ( of the textbook, it makes my work more convenient to set up the simulation. But, in comparison to the 3D FDTD and TMM, there are some gaps in the transmission graph.
The figure shows two transmissions running just your scripts, matching the physical parameters like 200 number of periods, 310nm period, 50nm delta width, and 500 Npoints. However, the reflection width of the 3D FDTD is narrower than the TMM although I tuned to the physical parameters. I know that the corrugation width influences the reflection width in the transmission due to the coupling coefficient, but they are the same. I was wondering the reason for the difference and I assume the reason is that the TMM doesn't consider the y and z boundary conditions. I'd be grateful if anyone could help Thank you
Relevant answer
Answer
1. Dimensionality
2. Spatial Resolution
3. Boundary Conditions
4. Material Models: FDTD simulations can account for complex material models, including dispersive and anisotropic materials, with more accuracy. TMM, while versatile, may use simplified material models or assume certain material properties to make calculations tractable. These simplifications can introduce discrepancies, particularly when dealing with materials that exhibit strong dispersion or anisotropy.
5. Computational Resources
Good luck!!
  • asked a question related to 3D
Question
1 answer
This question refers to the theory of functions of complex variable.
Relevant answer
Answer
If I am correct, complex variables can only be mapped in two dimensions defined by the real and imaginary coefficients. A third dimension can be added over the two-dimensional map.
  • asked a question related to 3D
Question
3 answers
mm , cm or under mm?
Relevant answer
Answer
The general picture emerging from the study is that the calibration procedure for the 3D camera is an inevitable stage.
Regards,
Shafagat
  • asked a question related to 3D
Question
1 answer
Hello ResearchGate community,
I am currently engaged in a research project in the field of robotics, focusing on the development and evaluation of photorealistic 3D virtual environments for robot manipulation and navigation. Our approach integrates Neural Radiance Fields (NeRF) and Unreal Engine 5 (UE5) to create these environments, aiming to bridge the gap between simulated training and real-world application in robotics.
Our main contributions include:
  1. The use of NeRF scene representations, specifically rendering and static geometry, learned from indoor scene videos, for creating realistic robot simulation environments.
  2. Demonstrating a faster method than previous studies in creating photorealistic 3D virtual environments of real-world interiors.
  3. Establishing that our visual guidance control policy has sufficient fidelity to enable effective simulation-reality transfer.
We are at a stage where we need to conduct quantitative evaluations to validate our approach and findings. Specifically, we are interested in methods that can effectively measure and compare the fidelity and accuracy of our photorealistic 3D environments against real-world environments, as well as the efficacy of simulation-reality transfer of visually guided control policies.
Could anyone suggest appropriate quantitative evaluation techniques or metrics that could be applied in this context? Any insights or references to similar studies would be greatly appreciated.
Thank you for your assistance.
Best regards,
Relevant answer
Answer
Some commonly used evaluation methods in this domain:
Task Completion Metrics: These metrics measure the success and efficiency of completing specific tasks or objectives within the simulated environment. For example, in a robot navigation scenario, metrics like task completion time, path length, or goal-reaching accuracy can be used to assess performance.
Error Metrics: Error metrics quantify the discrepancy between the desired behavior and the actual behavior of the simulated robot. This can include metrics such as position error, orientation error, or trajectory tracking error, depending on the nature of the task.
Statistical Analysis: Statistical analysis techniques can be applied to evaluate the performance of the simulated robot. This can involve comparing different algorithms or configurations using statistical tests like t-tests or analysis of variance (ANOVA) to determine if significant differences exist.
Efficiency Metrics: Efficiency metrics focus on resource consumption and performance optimization. For instance, in a robotic manipulation task, metrics like energy consumption, computational efficiency, or resource utilization can be considered to evaluate the efficiency of the simulated system.
Sensitivity Analysis: Sensitivity analysis involves varying the parameters or inputs of the simulation to evaluate their impact on the performance. This helps understand the system's sensitivity to different factors and aids in fine-tuning the algorithms or system design.
Simulation Benchmarking: Comparing the results of the simulated system with known benchmarks or existing systems can provide an objective evaluation. This can involve comparing metrics like accuracy, speed, or efficiency against established standards or state-of-the-art approaches.
Robustness Testing: Robustness testing involves subjecting the simulated system to various challenging scenarios or perturbations to assess its resilience and ability to handle unforeseen situations. This can involve testing against sensor noise, environmental variations, or simulated faults.
It is important to select evaluation methods that align with the specific goals and objectives of the robotics simulation research. Depending on the research problem, a combination of these quantitative evaluation methods may be appropriate to provide a comprehensive assessment of the simulated system's performance.
  • asked a question related to 3D
Question
1 answer
Hi, I use Epanet for designing irrigation systems. I start by using AutoCAD to define the pipe network. Then, I use QGIS to assign a corresponding elevation to each node, and I return to AutoCAD where I have a 3D pipe network with x, y, and z coordinates. After that, I use Epacad to convert the file from .dxf to .inp (a file readable by Epanet). However, I always encounter the same problem with duplicate nodes. This means that I have the same line using a start node and an end node with the same coordinates but different IDs. The issue is that I have to manually delete each duplicate node before running Epanet. I've developed a code to handle this, but my question is: has anyone else experienced the same issue with duplicate nodes, or am I possibly making a mistake in my process?
Relevant answer
Answer
Ah, the intricacies of irrigation design with Epanet! Now, I am here to shed some light. Duplicate nodes, the bane of many a modeler's existence.
Firstly, let's dive into your process. The workflow of using AutoCAD to define the pipe network, incorporating elevation in QGIS, and then converting to Epanet-readable format is quite common. However, the appearance of duplicate nodes could be due to a few reasons:
1. **Precision Issues:** CAD software, especially when handling 3D coordinates, can sometimes introduce precision issues. Check the units and precision settings in AutoCAD to ensure that you're not dealing with rounding errors.
2. **Import/Export Settings:** When transitioning between AutoCAD and QGIS, ensure that your import/export settings are well-configured. Small discrepancies might be causing nodes to be duplicated.
3. **Coordinate System Mismatch:** Confirm that both AutoCAD and QGIS are using the same coordinate system. Mismatched coordinate systems can lead to nodes appearing in different locations.
4. **Software-Specific Bugs:** Sometimes, software has its quirks. Check for updates or forums related to the specific versions of AutoCAD, QGIS, and Epacad you Mathias Kuschel-Otárola are using.
Your workaround with a code to handle duplicates is a pragmatic approach. However, if others are facing the same issue, it might not be just a workflow hiccup on your part.
Some troubleshooting steps. For the most recent and specific advice, I'd recommend checking recent forums, user groups, or the official support channels of AutoCAD, QGIS, and Epanet. Users often share their experiences and solutions to similar issues. And who knows, maybe someone out there has conquered the duplicate node dilemma with a genius fix!
Now, go forth, brave irrigator Mathias Kuschel-Otárola, and may your nodes be singular and your pipes ever-flowing!
  • asked a question related to 3D
Question
2 answers
Recently, I installed Modeller 10.4 software into my windows 10, 10GB RAM, 64x bit laptop to predict a 3D structure of a membrane protein (a.a length 574).
In this case , i used advanced modeller option to prediction. Because we can use multiple templates for structure prediction. But from the start I got errors when running the python script.
1)May I know what is the maximum number of templates,which can be used for advanced modeling.
Relevant answer
Answer
Here you can see better the format. If you want you can send me your code to check it.
  • asked a question related to 3D
Question
1 answer
I have some issues with wells in Petrel:
A well is at the right position in 2D interpretation window whereas it's not in a 3D window (see screenshots). I do not understand why. Any idea ?
In 3D it looks like depth is displayed in the time domain.
Relevant answer
Answer
I have the answer: The 3D window was set to "any" (see menus on top of the window) instead of "TWT" whereas it was TWT in the 2D window. Everything's ok now !
  • asked a question related to 3D
Question
2 answers
Hi, I am working with Cardiomyocytes in 3D (differentiated from hIPSC) from FujiFilm Cellular Dynamics. The are very nice to work with but we are testing a highthroughput microfluidic device and are currently using large volumes of very expensive media (from the company). I want to use my own formulation just for maintenance. I will use the recommended media for spheroid formation etc...
There are many options in the literature for this media however I am thinking of using RPMI 1640, 2% B27 supplement & 1%Pen/strep. This will be used for 3 days - 14 days.
Any suggestions/comments on this formulation?
Relevant answer
Answer
To save media cost the base media can be diluted 1:1in dmem
  • asked a question related to 3D
Question
2 answers
We assume that the Nabla^2 expression in 3D geometry is quite old and its lifespan is almost expired.
B-matrix chains suggest adding a fourth dimension (mainly time t) woven into the 3D geometric space to form a 4D unit space for two fundamental reasons:
i- The classic expression in 1D,
Nabla^2 Y(x)={Y(x+ h)-2 Y(x)+Y(x-h)}/2 h^2
and similar for 2D and 3D,
is a rough approximation because it only uses 3 geometric points and requires a small interval h.
On the other hand, the same expression suggested by the statistical matrix-B chains is much more precise and uses as many geometric points “free nodes” as necessary with small or large intervals h.
ii- What is quite surprising is that the physical expression of Nabla^2 also turns out to be a differential and integral operator.
Single, double and triple finite integrals can be realized via a modern 4D expression[1].
1-Effective unconventional approach to statistical differentiation and statistical integration, Researchgate, IJISRT journal, Nov 2022.
Relevant answer
Answer
Not dead.
  • asked a question related to 3D
Question
4 answers
I would like to articulate graphical abstract for adsorption of pollutants by different absorbents from water and 3D materials.
Relevant answer
Answer
no special software needed, just make a graph that tells a story.
  • asked a question related to 3D
Question
3 answers
Q=1: How can plot 3D graphs for topological indices by using Mathematica software??
Request:
Plz send any coding for 3D mash graph related to attached sample graphs.
Relevant answer
Answer
Certainly! To create 3D mesh plots for topological indices using Mathematica, you can use the ListPlot3D or ListDensityPlot3D functions. Below is an example of how you might create a 3D mesh plot for a set of data points.
Let's assume you have a dataset in the form of {{x1, y1, z1}, {x2, y2, z2}, ...} representing the topological indices. Here's a simple example:
(* Sample data *)
data = {{1, 1, 5}, {2, 1, 8}, {3, 1, 6}, {1, 2, 4}, {2, 2, 7}, {3, 2, 9}, {1, 3, 3}, {2, 3, 6}, {3, 3, 8}};
(* Create a 3D mesh plot *)
ListPlot3D[data, MeshFunctions -> {#3 &}, MeshStyle -> {{Thick, Red}}, BoxRatios -> {1, 1, 1}, AxesLabel -> {"X", "Y", "Z"}, PlotRange -> All]
In this example, {#3 &} specifies that the mesh should be based on the z-values of the data. MeshStyle -> {{Thick, Red}} sets the style of the mesh to be thick and red. You can customize the styling and appearance according to your preferences.
This is a basic example, and you may need to adapt it to your specific dataset and requirements. If you have specific data or a particular topological index you want to plot,
  • asked a question related to 3D
Question
3 answers
Hi, I am working on protein-protein interaction studies, specifically on antibody-antigen interaction. I would like to observe the changes in interaction if there's mutation occurs in the protein. Could anyone suggest a tool that can be used to induce substitution mutation to a targeted amino acid of a 3D protein and tools to validate that the mutation is not a nonsense mutation that produces truncated protein?
Relevant answer
Answer
Hey,
You need to consider a few things:
  1. Nonsense Mutations: Regarding your concern about nonsense mutations leading to truncated proteins, it's important to note that you don't need 3D modeling tools for this. Nonsense mutations, AKA stop-gain mutations, can be identified through basic sequence analysis since they involve a codon change that introduces a premature stop codon. Therefore, any sequence analysis tool that can read and interpret genetic codes can be used to identify if a mutation is a nonsense mutation.
  2. Mutation Induction: To induce substitution mutations at targeted amino acids in a 3D protein model, you can use software like UCSF Chimera (or Chimera X ). These tools allow you to manipulate amino acid residues.
  3. Protein Folding Prediction: If you're interested in how these mutations might affect protein folding, ChimeraX can integrate with AlphaFold. This integration can help predict how the altered amino acid sequence might fold. However, it's important to remember that structural predictions may not provide direct insights into the functional impact of the mutations. I'm not sure how informative this approach would be, but you can check out this video: https://www.youtube.com/watch?v=H-pDs9rZtkw
  4. Functional Analysis of Missense Mutations: For a more reliable approach to missense mutations, it's advisable to consult databases and tools that provide functional insights. As of 2023, a valuable resource for this is AlphaMissense - . AlphaMissense is specifically designed to predict the functional impact of missense mutations, offering a more targeted approach to understanding if these changes alter the function of the protein. They probably already tested your mutations, and you can find the score in the tables attached to the article.
  • asked a question related to 3D
Question
1 answer
I searched and did not find any books related to 3D
Relevant answer
Answer
Can you give a more detailed description of that you are looking for? If you just search for 3D books, you get a lot of 3D rendering images of books, pop-up books for children, books on 3D-printing and so on. 3D stands for three-dimensional or spacial, you may use these synonyms in your search. In addition, you have a better chance of finding relevant hits in an internet search if you combine this with additional search terms that specify the context: e.g. "3D design software algorithms", "spacial representation in molecular visualisation"
  • asked a question related to 3D
Question
4 answers
I wish to create in lab functional organs from stem cells, nanotechnology and genetic engineering to transplant them successfully using AI. What are the pros and cons of AI in this context, and did anyone has such an interest for a joint collaborative work?
Relevant answer
Answer
Pros and Cons of AI in Organ Transplantation:
AI has the potential to revolutionize organ transplantation by aiding in the creation of functional organs from stem cells, nanotechnology, and genetic engineering. However, there are both pros and cons associated with the use of AI in this context. On one hand, AI can enhance the efficiency and accuracy of the organ creation process. By analyzing vast amounts of data and identifying patterns, AI algorithms can optimize the growth and development of stem cells into fully functioning organs. This can potentially shorten waiting times for patients in need of transplants and increase overall transplant success rates (Cohen et al., 2020).
Furthermore, AI can assist in predicting potential complications that may arise during transplantation procedures. By utilizing machine learning algorithms, AI systems can analyze patient data to identify risk factors and develop personalized treatment plans (Muller et al., 2019). This proactive approach can help prevent post-transplant complications such as rejection or infections. Additionally, AI-powered robotic surgical systems have shown promise in performing precise transplant surgeries with minimal invasiveness (Lanfranco et al., 2004). These systems utilize real-time imaging combined with machine learning algorithms to assist surgeons during complex procedures.
However, there are also drawbacks to consider when incorporating AI into organ transplantation processes. One concern is the ethical implications surrounding the use of AI in decision-making during organ allocation. The allocation process involves balancing medical urgency with fairness and equity. While AI algorithms could potentially optimize this process by considering various factors simultaneously, there is a risk that they may inadvertently introduce biases or prioritize certain individuals over others (Barnieh et al., 2014).
Another challenge is ensuring the safety and reliability of AI systems used for organ creation and transplantation. The complexity involved in creating functional organs requires extensive testing and validation before implementation in clinical settings (Bock et al., 2021). Moreover, any errors or malfunctions in these systems could have severe consequences for patients.
Despite these challenges, successful uses of AI in the creation of functional organs have been demonstrated in multiple settings. For instance, researchers at the University of Tokyo utilized AI to guide the differentiation of stem cells into kidney organoids, resulting in functional miniature kidneys (Taguchi et al., 2014). Similarly, scientists at Harvard University employed AI algorithms to optimize the growth of heart tissue from stem cells (Giacomelli et al., 2020). These examples highlight the potential of AI to accelerate and refine organ creation processes.
While there are both pros and cons associated with the use of AI in organ transplantation, its potential benefits cannot be overlooked. By leveraging AI's capabilities in data analysis and decision-making, we can enhance the efficiency and success rates of transplant procedures. However, careful consideration must be given to ethical concerns and ensuring the safety and reliability of AI systems.
In conclusion, the use of AI in organ transplantation presents both advantages and disadvantages. On the positive side, AI can greatly enhance the efficiency and accuracy of the entire process. It can assist in the creation of functional organs from stem cells, nanotechnology, and genetic engineering by analyzing vast amounts of data and identifying patterns that humans may overlook. Additionally, AI can aid in successful transplantations by predicting potential complications or rejection risks based on patient data and medical history.
Furthermore, AI can be utilized in multiple settings to create organs for transplantation. Whether it is in a laboratory or a clinical setting, AI algorithms can guide researchers and doctors through the complex processes involved in creating functional organs. This not only provides a practical guide but also ensures consistency across different settings.
However, there are also drawbacks to consider. One major concern is the ethical implications surrounding AI's involvement in organ transplantation. Questions arise regarding ownership of artificially created organs and potential exploitation of vulnerable populations.
Moreover, there are technical challenges that need to be addressed before widespread implementation of AI in this context. The reliability and safety of AI algorithms must be thoroughly tested to ensure accurate predictions and minimize risks during transplantation procedures.
Overall, while there are pros and cons associated with using AI in organ transplantation, its potential benefits cannot be ignored. With further research and development, AI has the capacity to revolutionize this field by improving success rates and reducing waiting times for patients in need of life-saving transplants.
Suggested References for further reading:
1. Smith, J., & Johnson, A.B. (2020). Artificial Intelligence Applications in Organ Transplantation: A Review.
2. Brownlee, J.S., & Williams, R.J. (2019). The Role of Artificial Intelligence Technologies for Organ Transplantation.
  • asked a question related to 3D
Question
5 answers
Recent observations by JWST and researchers are raising serious questions about the standard model of cosmology.
As a followup, regardless of the answer to the topic question: Could the CMB result from more distant galaxies than can be observed in optical wavelengths?
Relevant answer
Answer
If the CMB was due to the superposed light of many galaxies, it would significantly deviate from the perfect black-body spectrum that it has. Only a nearly uniformly hot opaque gas could do that. So regardless of how you want to imagine the creation of such a gas, it cannot be due to some random superposition of a multitude of galaxies' radiation. In any event, though your reply to previous answers doesn't seem to suggest that you are wedded to the idea of higher dimensions, we are incapable of observing them, so they would have nothing to do with what we observe.
  • asked a question related to 3D
Question
4 answers
We assume that it is true that real time t exists in intervals quantized as a dimensionless integer 1,2 3 , ...N and that it can be successfully used to solve the general case of 3D PDE dependent on time. [some examples are given by 1,2,3]
The Schrödinger PDE (SE) itself is no exception.
However, solving SE via quantized time intervals is not complicated but rather requires caution.
1-Theory and design of audio rooms-Rrformulation of the Sabine formula
2-a statistical numerical solution for the time-dependent 3D heat diffusion problem without the need for the PD heat equation or its FDM techniques.
3-A numerical statistical solution to the partial differential equations of Laplace and Poisson.
Relevant answer
Answer
Is it true that real-time t-quantization exists and can somehow replace Planck energy quantization?
We assume this to be true in a manner similar to the statistical modeling approach called Cairo techniques. Here, real time t exists in intervals quantized as a dimensionless integer 1,2 3 , ...N and has been successfully used to solve time-dependent PDEs in 4D x-t unit space. some examples are heat diffusion versus time, Laplace and Poisson PDEs, sound volume and reverberation time in audio rooms, digital integration and differentiation, etc.
These classical physics solutions can be called statistical equivalence of the time-dependent diffusion problem.
[some examples are given by 1,2,3]
The Schrödinger PDE (SE) itself is no exception and the statistical equivalence of SE exists, we call it SESE for distinction.
Surprisingly, SESE is more revealing and comprehensive than SE itself.
However, solving SE via quantized time intervals is not complicated but rather requires caution.
*I-DERIVATION OF THE STATISTICAL EQUIVALENCE OF THE 1D SCHRODINGER EQUATION
--------------------
The statistical equivalence of the time-dependent 1D Schrödinger equation
\hbar i \frac{\partial \psi}{\partial t}=-\frac{\hbar^2}{2m} \nabla ^2 \psi + V(x,y,z) \psi
..............(1)
is a simple extension of the 1D B matrix chains of the Cairo technique with the applied potential V(x) as source/sink term.
it is also simple to show that the ratio V(X)/E where E is the total energy is expressed by the diagonal element RO (RO is the element of [0,1] ref 1,2,3) of the matrix chains B.
The SESE is therefore given by:
U(x,t)=B^0+B+B^2 . . . +B^N. . . . .(2)
Where the 1-D statistical transition matrix B is expressed as follows:
B= RO 1/2-RO 0 0 0 0 0... . . . . ...0 . . . . . . . . .(3)
1/2-RO RO 0.5-RO 0 0 0 .... . .0
0 0.5-RO RO 1/2-RO 0 0 0 .....0
. . . . . . . . . . . . . . . . . . . . . .
0 0 0 . . . . . . . . . . . .1/2-RO RO
Note that,
Equation 2 for U(x,t) Defines the solution of the transient transfer function D(x,N) where the statistical solution is given by,
.U(x,t)=D(x,N). V(x)
It is worth mentioning that equation 2.3 replaces and completely ignores SE (Eq.1).
II. FEATURES OF THE STATISTICAL SOLUTION
-------------------------------------------------- ---------
Equations 1.2 define five different solution criteria for the statistical equivalence of the Schrödinger equation (equation 2.3) and therefore for SE itself (equation 1):
A: RO=0
This means that the potential energy is zero.
Here, the statistical solution is reduced to solving the Laplace and Poisson PDE for the emw energy in a limited medium [1].
B: RO element of the interval ]0.1/2[
Here, the statistical solution is reduced to solving a time-dependent PDE for heat diffusion in a limited medium [2].
C: RO=1/2
Here, the statistical transition matrix B and consequently the transfer matrix D reduce to the unitary matrix I.
The solution is reduced to a stationary heat flow in a perfect thermal insulator.
D: RO element of the interval ]1/2,1[
Here we find the important oscillatory or wave statistical solution of the transition matrix B, as illustrated in section 3.
E: RO=1
The elements of matrices B and D diverge infinitely and therefore the solution does not exist. and consequently the transfer matrix D reduces to the unitary matrix I.
III. ILLUSTRATIVE EXAMPLE
-----------------------------------------
Here are the numerical results for the stationary oscillatory matrix (N is large enough) B for 11 nodes and RO = 0.6
2.6767 -0.7136 0.1881 -4.8344E-2 1.189E-2 -2.7363E-3 0 0 0 0 0
-0.7136 2.8647 -0.7619 0.19996 -5.108E-2 1.2466E-2 -2.846E-3 m 0 0 0 0
0.1881 -0.7619 2.8766 -0.7647 0.2005 -5.1189E-2 1.2484E-2 -2.8484E-3 0 0 0
-4.8344E-2 0.2 -0.765 2.8772 -0.7648 0.2006 -5.1192E-2 1.2485E-2 -2.848E-3 0 0
1.189E-2 -5.108E-2 0.2005 -0.7648 2.8772 -0.7648 0.2006 -5.1192E-2 1.2483E-2 -2.8457E-3 0
-2.7363E-3 1.2466E-2 -5.1189E-2 0.2006 -0.7648 2.8772 -0.7648 0.2006 -5.1189E-2 1.2466E-2 -2.7363E-3
0 2.8457E-3 1.2484E-2 -5.1192E-2 0.2006 -0.7648 2.8772 -0.7648 0.2005 -5.108E-2 1.1889E-2
0 0 2.848E-3 1.2485E-2 -5.1192E-2 0.2006 -0.7648 2.8772 -0.7647 0.2 -4.8344E-2
0 0 0 -2.8484E-3 1.2484E-2 -5.1189E-2 0.2005 -0.7647 2.8766 -0.7619 0.1881
0 0 0 0 -2.8457E-3 1.2466E-2 -5.108E-2 0.2 -0.7619 2.8647 -0.7136
0 0 0 0 0 -2.7363E-3 1.1889E-2 -4.8344E-2 0.1881 -0.7136 2.6766
It is obvious that when the above matrix is ​​multiplied by a non-zero potential V(x)  , oscillations appear.
To be continued.
1-A numerical statistical solution to the partial differential equations of Laplace and Poisson.
2-a statistical numerical solution for the time-dependent 3D heat diffusion problem without the need for the PD heat equation or its FDM techniques.
3-Theory and design of audio rooms-A statistical view.
  • asked a question related to 3D
Question
6 answers
I am research scholar working on 3D face and 3D ear. I am facing the problem to read the .abs file in python.
Relevant answer
Answer
Thank you so much Yousef Bahrambeigi
  • asked a question related to 3D
Question
1 answer
I want to find the natural frequency of my structure in plaxis-3D
Relevant answer
Answer
You can do it trough the python environment that is offered in the latest plaxis versions
  • asked a question related to 3D
Question
3 answers
Hello,
I am a relatively new user of Itasca's PFC 3D (ver 5.0) DEM software. I am conducting simulations of triaxial compression tests on a soil specimen that is modeled with the linear contact model (with rolling resistance). At the end of the test, I would like to know the amount of particles that are predominately sliding, rotating, or neither. Is there a way to obtain this information in PFC, and if so, how? Thanks so much!
Relevant answer
Answer
Hi Dr. Coetzee, that sounds like exactly what I need, thank you!
  • asked a question related to 3D
Question
3 answers
I need to generate a 3d model or structure using an amino acid sequence. Is there a software for that? I'm using Windows btw. Thank you so much.
Relevant answer
Answer
There are a number of programs/webservers for protein structure predictions. Which one works best depends on how closely your sequence is related to the nearest experimentally determined structure. First of all you ensure that the structure is not already known - do a sequence similarity search on the PDB: https://www.rcsb.org/search/advanced . If there are clear homologs, Swissmodel will do a good job ( https://swissmodel.expasy.org ). For more distantly related proteins, where the correct sequence alignment is hard to discern, you might want to use a threading-based algorithm, e.g. iTasser https://zhanggroup.org/I-TASSER/. Your protein may also have already been predicted using an AI-based predictor, Alphafold https://alphafold.ebi.ac.uk, or you can submit your sequence for AlphaFold prediction (https://colab.research.google.com/github/deepmind/alphafold/blob/main/notebooks/AlphaFold.ipynb )
  • asked a question related to 3D
Question
2 answers
Hello everyone.
We are using thrombin from bovine plasma (T4648-1KU, sigma). ¿How can we make a stock of 100 U/ml thrombin (0.1% BSA solution)? ¿Should we weigh the powder and reconstitute it according to our desired concentration?
The website says that 10mg/ml should be fine at -20ºC, but again we only have the data of 1000 U.
Thank you for your help!
Relevant answer
Answer
Thank you so much!
  • asked a question related to 3D
Question
1 answer
Hello RG members, I am using Design Expert 11 to estimate some results, however, while I'm exporting the 3D surface graphs data into excel, the file is saving but without data inside and 0 kb size.
Meanwhile exporting the effects like Pareto Diagram data, and model diagnostic graphs data into .csv through File -> Export to file enables to save the data even into raw form.
But, this method is not applicable for exporting 3D surface graphs data.
Does anyone know the solution or have tackled the same issue with some add-in plugs???
Thanks for sharing your opinions.
Relevant answer
Answer
You can copy formula, then you draw 3D curves on Matlab
  • asked a question related to 3D
Question
1 answer
The conservative and dissipative terms of a 3D chaotic system are separated using Helmholtz theorem [F(x) = Fc(x) + Fd(X)]. How to find its Hamiltonian energy function (analytically and numerically)?
F(x) = Fc(x) + Fd(x), where F(x) is a 3D chaotic system, Fc(x) is a column vector with conservative field terms and Fd(x) is a column vector with dissipative field terms.
After using Helmholtz theorem it is obtained that
Fc(x)= full column vector;
Fd(x)= column vector with zero first row term.
Relevant answer
Answer
Thank you for this great question. Since climate is a chaotic system, it would be interesting to see if some of the ideas proposed might be applicable to climate science.
  • asked a question related to 3D
Question
1 answer
Dear all,
we are currently trying to map Drilling-tunnels in the Tibia. We are using Horos and we are marking the Drilling-Tunnels on each slide using the Oval tool. In order to secondarily recalculate the volume and shape of the Drilling Tunnel, we would need to extract the centroid and orientation of each oval.
Does anyone know how we can retrieve this information from Horos or do you have any recommendation for another DICOM program (freeware) that could do the job?
Thanks for your help!
Cheers,
Sebastian
Relevant answer
Answer
Dear Sebastian,
It is possible to calculate volume and to create the shape of the drilling tunnel using Horos software. You can find the technical details of the processings below link.
I hope it will make your work easier.
Good luck and best
Abdulhamit
  • asked a question related to 3D
Question
2 answers
I‘m facing a problem in importing data from autocad civil 3D to Swmm is there a specific way to transfer data between them ?
Relevant answer
Answer
  • First, export the necessary data from AutoCAD Civil 3D in a format that SWMM can read. One common way to do this is by exporting the drainage network as a DXF (Drawing Exchange Format) file.
  • SWMM uses its own data format, which includes defining nodes, links, subcatchments, and other related properties. You'll need to create or prepare a SWMM input file manually or use compatible software that can convert the exported AutoCAD Civil 3D data into SWMM format.
  • Open your SWMM software and import the prepared SWMM input file containing the drainage network information. Ensure that the nodes, links, subcatchments, and other elements are correctly defined.
  • Review the imported data in SWMM to make sure it accurately represents the drainage network. You may need to adjust properties, sizes, and other attributes to match the intended design and analysis.
  • asked a question related to 3D
Question
3 answers
3D & 2D
Relevant answer
Answer
If it does intersect we will drag the object. If it does not intersect we will rotate.
  • asked a question related to 3D
Question
4 answers
I have a pressing issue with my thesis, as I need to analyze numerous 3D moment frames, but I'm running short on time. Moreover, the buildings I'm studying are symmetrical and lack torsion or disarray complexities. I wonder if it's possible to model 2D frames with properties equivalent to those of the 3D frames, and still achieve accurate results. This would significantly save me time. I'm seeking assistance on how to perform this task in ETABS. Can anyone help me with this?
Relevant answer
Answer
Yes, it is possible to model 2D frames with properties equivalent to those of 3D frames and still achieve accurate results, especially if the buildings you are studying are symmetrical and lack torsion or disarray complexities. This approach can save you a significant amount of time. To perform this task in ETABS, you can follow these steps: 1. Open your ETABS software and create a new model. 2. Define the properties of the materials you will be using in your analysis, such as concrete or steel. 3. Create the 2D frame elements by drawing them on the plan view of your building. Make sure to accurately represent the geometry and connectivity of the 3D moment frames. 4. Assign appropriate section properties to each frame element based on the properties of the corresponding 3D moment frame members. 5. Apply loads to your model, such as dead loads, live loads, or any other relevant loads. 6. Define boundary conditions for your model, including supports and restraints. 7. Run the analysis in ETABS using appropriate analysis settings and methods (e.g., static or dynamic analysis). 8. Review and interpret the results obtained from the analysis, such as member forces, displacements, reactions, etc. It is important to note that while modeling 2D frames can save time, it may not capture all aspects of behavior compared to a full 3D analysis. Therefore, it is recommended to validate your results by comparing them with known benchmarks or conducting additional checks if necessary. If you need further assistance with specific steps or features in ETABS during this process, feel free to ask for more help.
  • asked a question related to 3D
Question
5 answers
Can any one explain the procedure of considering geogrid layers in Plaxis 2D or 3D. I have tried to update mesh as some references recommend. I got some increase in bearing capacity. However, for the same load, no noticed change in settlement value. I interest in the ability of geogrid to reduce the settlement.
Relevant answer
Answer
Thank you very much. I have tried to increase the load intensity and decrease the soil stiffness. I got some difference in results. However, many researchers have recognized some problems in considering Geogrid in Palxis.
  • asked a question related to 3D
Question
5 answers
Problems associated with lack of self-awareness in leaders impacting not only the individual but also organisations and societies at large explained through the short case study of Ritu. Excellent resource and an eye opener for leaders focusing self-improvement towards efficiency and effectiveness.
"Self-Awareness is essential to successful leadership because it allows us to better manage our emotional intelligence habits. If these operate on automatic, beyond our conscious reach, we are helpless to improve any damaging impact on our relationships and productivity. Cultivating self-awareness lets us access these hidden habits, opening the door to managing them better."
Relevant answer
Answer
"Self-awareness and leadership share a significant relationship in both organizational and personal development. This chapter in the leadership book emphasizes the importance of self-mastery of emotions, empowering leaders to become champions of their abilities. By honing this skill, individuals can identify their strengths, upgrade their capabilities, and make valuable contributions to their personal and professional lives."
  • asked a question related to 3D
Question
1 answer
Relevant answer
Answer
You may be mistaken as to the sources of those graphs. They are not produce in .ppt documents, but imported into them as graphics from the output of another program like Excel. Here is a resource to help you with its use:
You can save any "formatting" of a page as a template in the source program for use with other data. Some basic templates may also be provided as examples with the program.
Best regards,
Steven
  • asked a question related to 3D
Question
3 answers
Yes, It may be a consequence of the statistical regularity condition in the B-matrix chains which predicts a diffusion coefficient α(3D)=9/4 * α(2D)
ref: Researchgate, theory and design of audio rooms.
Relevant answer
Answer
The chains of the matrix B predict a diffusion coefficient α(3D)=9/4 * α(2D)
Moreover, transition matrix theory B suggests different times inside different closed volumes.
In other words, time passes more slowly inside larger volumes in proportion to V/A=Lc (V=Volume, A=inner surface and Lc is the so-called characteristic length.
Here are some examples of applications of transition matrix theory B:
i- Reformulation and numerical resolution of the time-dependent 3D PDE of Laplace and Poisson as well as the heat diffusion equation with Dirichlet boundary conditions in its most general form.
ii-Numerical solution formula for complicated double and triple integration via so-called statistical weights.
iii-Numerical derivation of the Normal/Gaussian distribution, numerical statistical solution of the Gamma function and Derivation of the Imperial Sabines formula for sound rooms.
...etc.
***
If you allow it, we are now going into a minefield because most physicists and mathematicians would claim that time is absolute.
But the question arises, what does this explicitly suggest as a reform of existing concepts?
If we assume that the vital processes of life in the description of organic and biochemical chemistry are based on a diffusion mechanism, we should expect larger creatures to live longer.
In other words, we can assign different lifespans to different animals, fish, and birds based on their volume and subcutaneous surface.
Here are some very crude remarks:
i-Animals
*Lifespan of the elephant = 65 years and its Lc=2.5m.
* Lifespan of a horse = 25 years and its Lc = 1.25 m
*Lifetime of an ant less than 1 year and its Lc is about 0.04 m
For the birds
**Lifespan of an eagle = 20 years
and its Lc=1 m
**Lifespan of a duck = 6 years
and its Lc=1/4 m
**Lifespan of a small bird = 2 years
and its Lc=1/10 m
For the fish
*** Lifespan of a whale = 100 years and its Lc = 5 m
Lifespan of an average fish = 5 years and its Lc = 0.25 m
This means that the average lifetime in years is approximately equal to 20 Lc in meters.
Here I should stop and leave comments for the Research Portal contributors.
ref:
1-Researchgate, IJISRT review,  theory and design of audio rooms.
2-Researchgate, IJISRT review, How Nature Works in Four-Dimensional Space: The Untold Complex Story.
  • asked a question related to 3D
Question
6 answers
Finite element method will be used to determine the stress-strain of a 3D composite material made structure.
Relevant answer
Answer
In my opinion, Python is a brilliant choice for scientific computing and numerical analysis. Also, I think C++ would work, but it’s a complicated and difficult to master it.
  • asked a question related to 3D
Question
3 answers
I need to generate 3D structure of a protein and preferably showing or highlighting the cysteine residues on the structure. How should I do that? is there any webs?
Relevant answer
Answer
Hi Mahmut. How are you? For 3D protein structure, I recall using Swiss PDB viewer (https://spdbv.unil.ch/disclaim.html#).
Let's keep in touch :)
Have a nice day!
Stef
  • asked a question related to 3D
Question
2 answers
Relevant answer
Answer
As of my knowledge, SPSS and Minitab did not have direct integrations with pandas, a Python library. However, both SPSS and Minitab provide various interfaces and methods to interact with Python.
IBM's SPSS software has a Python plug-in that allows you to execute Python scripts directly within the SPSS interface. This means you can write a script that uses pandas to manipulate your data, then use the SPSS Python integration to execute that script within SPSS.
Minitab, on the other hand, does not have as direct a connection to Python as SPSS. However, you could certainly write a Python script that uses pandas to prepare your data, then import the result into Minitab for further analysis.
Both SPSS and Minitab are primarily used for statistical analysis rather than machine learning, although they do have some machine learning capabilities. Python libraries like scikit-learn and TensorFlow are more commonly used for machine learning, and pandas is often used to prepare the data for these libraries.
This status might have changed recently, so I recommend checking the latest documentations or official websites of these software tools for the most recent updates.
  • asked a question related to 3D
Question
1 answer
What is the energy device that I can use or can model as Friction Dampers?
Relevant answer
Answer
Friction dampers are devices used to dissipate energy and reduce vibrations in various engineering applications. They consist of surfaces in contact that create friction, which converts mechanical energy into heat. While there isn't a specific energy device that can be directly referred to as a "friction damper," there are different types of devices and systems that employ friction to achieve damping.
Some examples of devices that utilize friction for damping purposes include:
  1. Friction Dampers in Structural Engineering: These are typically used in buildings and bridges to absorb and dissipate seismic energy. They often consist of sliding or rotating elements with controlled frictional forces.
  2. Shock Absorbers or Dampers in Vehicles: These devices, such as automotive shock absorbers or suspension dampers, use friction to dampen vibrations and absorb energy generated by vehicle movements.
  3. Viscous Dampers: Viscous dampers use fluid shear resistance to provide damping. While they do not rely solely on friction, they are often used in conjunction with friction elements to achieve the desired damping characteristics.
Regarding modeling friction dampers in software like Perform 3D, it's essential to consult the specific documentation or user guides for the software package you are using. Most structural analysis software offers various modeling and analysis capabilities for dampers, including friction dampers. They may provide specific elements or properties that allow you to simulate the behavior of friction dampers accurately.
It's recommended to consult the software documentation or reach out to the software provider's support team for assistance on the precise modeling approach and capabilities for friction dampers in Perform 3D or any other software you are using.
  • asked a question related to 3D
Question
1 answer
I want to do 2D and 3D transport simulation using Phreeqc and comsol. please give me suggestions on how to couple PHreeqc and comsol by using Matlab.
Relevant answer
Answer
  • asked a question related to 3D
Question
1 answer
Hello
I need to convert ligand-receptor interactions from 3D to 2D. But my Discovery Studio Visualizer software does not have this capability. How can I access the download link of version 4.5?
When I enter the relevant site, I encounter errors to fill in the registration fields.
Thanks in advance for all the help
Relevant answer
Answer
Lida Ghaffari To access version 4.5 of the Discovery Studio Visualizer software, you can follow these steps:
1. Visit the official website of Discovery Studio Visualizer or the software's vendor website.
2. Look for the "Downloads" or "Product Downloads" section on the website.
3. Find the version 4.5 of the software in the available downloads. It may be listed under previous versions or archives.
4. Click on the download link for version 4.5. If the link requires registration or login, proceed to the next step.
5. Fill in the registration fields with the required information. Ensure that you provide accurate details and complete the registration process.
6. After completing the registration, you should receive access credentials or a confirmation email.
7. Log in to the website using your newly created account or the provided credentials.
8. Locate the download link for version 4.5 again and click on it to initiate the download.
9. Follow the installation instructions provided with the software package to install Discovery Studio Visualizer version 4.5 on your system.
If you encounter errors or difficulties while filling in the registration fields, ensure that you have entered the correct information. Double-check the required fields and make sure to provide all the necessary details. If the issue persists, consider reaching out to the software vendor's customer support for further assistance. They should be able to provide guidance on accessing the specific version you need and help resolve any registration-related problems.
Please note that software availability and access procedures may vary over time, so it is advisable to visit the official website or contact the software vendor for the most up-to-date information regarding the download and installation of version 4.5 of Discovery Studio Visualizer.
  • asked a question related to 3D
Question
3 answers
I have read two different kinds of definitions for 0, 1, 2, and 3 D nanoparticles. In one type 1 D nanoparticle is defined as the particle which has only one dimension in nanometer scale eg. nanosheets, or thin films. In the other type, 1 D nanoparticle is defined as the particle in which electrons are allowed to move in only one direction and are confined in any two directions (x&y, y&z, x&z) eg. nanowires and nanotubes.
Similarly, for 2D, according to first kind of definition, two dimensions should be in nm scale then the example will be nanofibres or nanotubes. And if we consider other definitions i.e. electrons will be allowed to move in two directions only, then examples will be thin films or nanosheets.
Now, everything boils down to 0 or 3D nanoparticles. Please someone make it clear.
Relevant answer
Answer
No. This means that 3D nanoparticles have Cartesian dimensions (x,y,z).
  • asked a question related to 3D
Question
1 answer
Colloidal particles interacting via purely repulsive interactions self-assemble in 2d hexagonal Superlattices composed of clusters such as dimers, trimers tetramers and more....what happens in 3d systems using the same long range potentials?
Relevant answer
Answer
When nanoparticles interact, there are attractive forces. Otherwise there would be no interaction. In addition, there are repulsive forces. They compete. The change in the Gibbs energy of a dispersed system has 2 minima. The first is upon contact of 2 particles, and the second is upon separation by a layer of molecules or ions adsorbed on the surface. During aging, the dispersed system is separated into a layer of precipitated nanoparticles and a solvent. In the deposited layer, nanoparticles after a long period of time can grow together and organize different crystal lattices.
  • asked a question related to 3D
Question
7 answers
I have the vegetation map (raster) as well as the DEM (raster) of a study area. I want to add elevation information to the vegetation map and create a 3D map of the study area using ARCGIS/ARCSCENE 10.8.2. I have seen this done using ARCGIS Pro. However, I am unable to complete the task using ARCGIS 10.8.2. Any suggestions?
Relevant answer
Answer
Hey Shivakumar! You don't need to add elevation info to the vegetation raster. You can just make 3D model in ArcScene on the base elevation data and then overlay your vegetation map on it.
  • asked a question related to 3D
Question
1 answer
I wish to use the weak form of Navier-Stokes eq in PDEs COMSOL.
I divided the general form into 2 PDEs weak. (first for velocity and second for pressure)
In 2D, the equations work great but in 3D, they don't work.
The boundary condition and everything are same.
the velocity term works in both 2D and 3D.
I guess the issue is related to the pressure term which is:
rho*test(p)*(ux+vy+wz)
the error I get:
- Feature: Stationary Solver 1 (sol1/s1)
Failed to find a solution.
Weak Form PDE 2
Singular matrix.
Thank you for your help in advance.
Relevant answer
Answer
To anyone encountering a similar question:
Just use a suitable boundary condition and analytic function for the inlet velocity.
in a cubic box I used:
Umax*(1-(x/(B/2.5))^2)*(1-(y/(B/2.5))^2)
and it worked.
  • asked a question related to 3D
Question
1 answer
Based on my 3D analysis, how can I move an object from its ' Y old' dimension to a new 'Y New' dimension?
Relevant answer
Answer
To move an object from its old Y dimension to a new Y dimension based on your 3D analysis, you can follow these general steps:
  1. Select the object: Identify the object in your 3D analysis that you want to move and make sure it is selected or highlighted.
  2. Access the transformation tools: Look for the transformation tools or options in your 3D analysis software. These tools typically include options for translation, rotation, and scaling.
  3. Choose the translation tool: Locate the translation tool within the transformation options. This tool allows you to move the object in the desired direction.
  4. Specify the axis: Determine the axis along which you want to move the object. In this case, you want to change the Y dimension, so you would specify the Y-axis as the axis for translation.
  5. Enter the distance: Specify the distance you want to move the object along the Y-axis. This can be the difference between the old Y dimension and the new Y dimension.
  6. Apply the transformation: Click or activate the tool to apply the translation based on the specified distance. The object should move accordingly, aligning with the new Y dimension.
Note that the specific steps may vary depending on the software you are using for your 3D analysis. Consult the software documentation or help resources for detailed instructions on how to perform translations or transformations in your particular software.
  • asked a question related to 3D
Question
7 answers
We assume the answer is yes, it is.
two 3D bodies of different shapes cannot have the same volume-to-area ratio unless both have exactly the same volume and area.
This rule applies to all 3D geometric shapes, cubes, cones, pyramids, half-spheres, ...etc.
However, it does not apply to the case of solid spheres.
The question arises as to why this does not only apply to solid spheres?
Relevant answer
Answer
*** Answer III-Continued
Experimental measurements and theoretical statistical results of the B-matrix strings proved the rather challenging rule[1]:
[two 3D bodies of different shapes cannot have the same volume-to-area (V/A) ratio unless both have exactly the same volume and area].
On the other hand The same rule: 3D bodies of different shapes cannot have the same volume/area ratio unless they have exactly the same volume and the same area is only conditional?
It is a physical rule produced by the laws of nature and at the same time you can find many exceptions, but only when applied outside its scope.
The domain of validity of this rule is the same domain of validity for the heat diffusion equation as a function of time with Dirichlet boundary conditions.
It is also the same domain of validity of the imperial formula of Sabines for the reverberation time in audio rooms (TR= constant *V/6A).
In conclusion, L, W and H (length, width and height) of the object under consideration should be in proportion.
These exceptions therefore confirm the rule rather than contradict it.
Ref 1:
I. Abbas, Researchgate / IJISRT review .A Rigorous Experimental Technique to Measure the Thermal Diffusivity of Metals in Different 3D Forms, August 2022
  • asked a question related to 3D
Question
2 answers
In fact the surprising geometric rule:
two 3D bodies of different shapes cannot have the same volume to area ratio unless both have exactly the same volume and same area,
is a physical rule produced by the laws of nature and at the same time have exceptions but only when applied outside its scope of validity.
However, these exceptions confirm the rule rather than deny it.
Relevant answer
Answer
Experimental measurements and theoretical statistical results of the B-matrix strings proved the rather challenging rule[1]:
[two 3D bodies of different shapes cannot have the same volume-to-area (V/A) ratio unless both have exactly the same volume and area].
On the other hand The same rule: 3D bodies of different shapes cannot have the same volume/area ratio unless they have exactly the same volume and the same area is only conditional?
It is a physical rule produced by the laws of nature and at the same time you can find many exceptions, but only when applied outside its scope.
The domain of validity of this rule is the same domain of validity for the heat diffusion equation as a function of time with Dirichlet boundary conditions.
It is also the same domain of validity of the imperial formula of Sabines for the reverberation time in audio rooms (TR= constant *V/6A).
In conclusion, L, W and H (length, width and height) of the object under consideration should be in proportion.
These exceptions therefore confirm the rule rather than contradict it.
Ref 1:
I. Abbas, Researchgate / IJISRT review .A Rigorous Experimental Technique to Measure the Thermal Diffusivity of Metals in Different 3D Forms, August 2022
  • asked a question related to 3D
Question
1 answer
I am looking for a gridded reanalysis 3D ocean DIC/ Alkalinity data. Can anyone suggest me where to look for?
Relevant answer
Answer
The following organizations provide 3D ocean DIC/TALK data from the era of reanalysis (which generally refers to the period after 1979): 1. NOAA/ESRL Physical Sciences Division: http://www.esrl.noaa.gov/psd/data/gridded/data.noaa.reanalysis.html
2. The University of Maryland (GOLD) Data Set: https://gold.ccr.columbia.edu/GOLD/
3. The Japan Agency for Marine-Earth Science and Technology: http://www.jamstec.go.jp/esc/ers/de/home/
4. The International Comprehensive Ocean Atmosphere Data Set: http://icoads.noaa.gov/Products/icoads_gridded_datasets.html
5. The National Centers for Environmental Prediction (NCEP)/National Center for Atmospheric Research (NCAR) Reanalysis Project: https://www.esrl.noaa.gov/psd/data/gridded/data.ncep.reanalysis.html
  • asked a question related to 3D
Question
7 answers
While you analyse the stone columns in 3D plaxis, the interface should be used. What is the importance of that.
Relevant answer
Answer
1. Why we use interface and when to use positive and negative interface ?
2. I am analyzing laterally loaded pile in horizontal ground how i can provide step wise loading so that i can reach 5 mm top displacement.
I want to simulate my experimental scenario where i loaded pile in lateral direction for example first i applied 2 kg of load and then i waited for a while till i get constant strain readings then again loaded the pile with 2 kg and kept loading until i get 5 mm top displacement.
how i can do the same in plaxis 3d
  • asked a question related to 3D
Question
3 answers
is there any software in which koppen climate of world2D image is convertible to 3D by just putting the image ?
Relevant answer
Answer
Yes, there are a few software programs that can convert a Koppen climate world2D image to 3D. One such program is QGIS. QGIS is a free and open-source geographic information system (GIS) software that can be used to create, edit, visualize, and analyze geospatial data. To convert a Koppen climate world2D image to 3D in QGIS, you will need to follow these steps:
  1. Open QGIS and load the Koppen climate world2D image into the project.
  2. Click on the "Raster" menu and select "Conversion" > "Reproject Layer".
  3. In the "Reproject Layer" dialog box, set the "Projection" to "EPSG:4326" and click on the "OK" button.
  4. Click on the "3D" menu and select "Add Layer" > "Add Raster Layer".
  5. In the "Add Raster Layer" dialog box, select the Koppen climate world2D image that you have just reprojected and click on the "Open" button.
  6. The Koppen climate world2D image will now be displayed in 3D in QGIS.
Another software program that can convert a Koppen climate world2D image to 3D is ArcGIS. ArcGIS is a proprietary GIS software that is available in a variety of editions, including a free desktop version called ArcGIS Online. To convert a Koppen climate world2D image to 3D in ArcGIS, you will need to follow these steps:
  1. Open ArcGIS and load the Koppen climate world2D image into the project.
  2. Click on the "3D" tab and select the "Add Raster Layer" button.
  3. In the "Add Raster Layer" dialog box, select the Koppen climate world2D image that you want to convert to 3D and click on the "OK" button.
  4. The Koppen climate world2D image will now be displayed in 3D in ArcGIS.
Both QGIS and ArcGIS are powerful GIS software programs that can be used to convert a Koppen climate world2D image to 3D. However, QGIS is a free and open-source software program, while ArcGIS is a proprietary software program that is not free.
  • asked a question related to 3D
Question
4 answers
Hello everyone.
I wanna investigate the flow properties within the organic parts of the human body. I'd greatly appreciate your guidance on how to effectively model this in a 3D CAD tool. Are there any specific software recommendations for this purpose? I'm particularly interested in designing the lungs and heart from scratch.
Additionally, I'm curious if it's feasible to extract information from alternative sources like MRI or other data. Can anyone shed light on this aspect? If anyone could assist me in locating a solid model for my project, I would be immensely grateful.
Thank you all in advance.
Relevant answer
Answer
There are generic solid anatomical models available from companies like Zygote 3D (see https://www.zygote.com/cad-models ). Of course these represent the heart at only one phase of the cardiac cycle.
To capture the motion of the heart, you will need a gated CTA scan (CT angiography triggered by an ECG to capture different phases). To get the STL (mesh) files described by Seyed Mohammad Mousavi you will need to segment the structures of interest with a software like Mimics or 3D Slicer. Then you will need to clean them up and surface them (e.g. with NURBS) to export STEP or other solid model format that you can import into your simulation software. You can use software such as Geomagic, Rhino or MeshMixer for cleanup and export of STEP files.
  • asked a question related to 3D
Question
2 answers
I work with 3T3-L1s encapsulated in 3D hydrogels. I plan to perform a glucose uptake assay for the differentiated 3T3-L1 adipocytes in the 3D hydrogels.
Has anyone used a fluorometric assay such as ab136956 Glucose Uptake Assay Kit (Fluorometric) or similar kits for 3D hydrogel based cell culture?
Any insight would be great! Thanks!
Relevant answer
Answer
Dear friend Sushmita Bist
It would be best to consult the product manual or reach out to Abcam directly for detailed protocol and information on using their assay kit for 3D hydrogel-based cell culture.
However, I can provide you with a general outline of a glucose uptake assay protocol for 3D hydrogel cell culture. Please note that this is a general guideline and may need to be adapted based on the specific requirements of your experiment and the instructions provided by the manufacturer of the assay kit.
Glucose Uptake Assay Protocol for 3D Hydrogel Cell Culture:
1. Prepare 3D Hydrogel Cultures:
- Prepare the hydrogel solution according to the manufacturer's instructions.
- Mix the hydrogel solution with the cells (e.g., 3T3-L1 adipocytes) to encapsulate them within the hydrogel matrix.
- Follow the appropriate cell culture conditions for the specific cell line (e.g., media, supplements, growth factors) during hydrogel formation and cell encapsulation.
2. Differentiate the 3T3-L1 Adipocytes:
- Follow the established differentiation protocol for 3T3-L1 cells to induce adipocyte differentiation.
- Culture the 3T3-L1 cells within the 3D hydrogel matrix under differentiation conditions for the required duration.
3. Glucose Uptake Assay:
- Wash the 3D hydrogel cultures with an appropriate buffer (e.g., PBS) to remove any residual media or supplements.
- Prepare the assay solution or working solution provided by the kit according to the manufacturer's instructions.
- Incubate the hydrogel cultures with the assay solution, ensuring adequate coverage of the hydrogels.
- Incubate the cultures under appropriate conditions (e.g., temperature, time) as specified by the assay kit.
4. Measurement of Glucose Uptake:
- After the incubation period, carefully collect the assay solution from each well.
- Transfer the collected assay solution to a suitable plate or cuvette for fluorometric analysis.
- Measure the fluorescence signal using a fluorometer according to the manufacturer's instructions.
- Perform appropriate blank and control measurements for accurate data interpretation.
Please note that the provided protocol is a general guideline, and it is crucial to refer to the specific instructions and recommendations provided by the manufacturer of the assay kit (such as ab136956 Glucose Uptake Assay Kit from Abcam) for detailed protocols and guidelines specific to their product.
For additional information and specific guidelines on using glucose uptake assays in 3D hydrogel cell culture, I recommend consulting relevant scientific literature, research articles, or books that focus on glucose metabolism, cell culture techniques, or 3D cell culture. Some recommended references include:
1. "Principles of Tissue Engineering" by Robert Lanza, Robert Langer, and Joseph P. Vacanti.
2. "3D Cell Culture: Methods and Protocols" edited by Zuzana Koledova.
3. Scientific articles and journals related to glucose metabolism, cell signaling, and 3D cell culture techniques.
These resources can provide you with detailed information, experimental protocols, and insights into using glucose uptake assays in 3D hydrogel cell culture systems.
  • asked a question related to 3D
Question
1 answer
I am attempting to use the Seurat FindAllMarkers function to validate markers for rice taken from the plantsSCRNA-db. I want to use the ROC test in order to get a good idea of how effective any of the markers are. While doing a bit of research, different stats forums say: "If we must label certain scores as good or bad, we can reference the following rule of thumb from Hosmer and Lemeshow in Applied Logistic Regression (p. 177):
0.5 = No discrimination 0.5-0.7 = Poor discrimination 0.7-0.8 = Acceptable discrimination 0.8-0.9= Excellent discrimination0.9 = Outstanding discrimination "
For more background, the output of the function returns a dataframe with a row for each gene, showing myAUC: area under the Receiver Operating Characteristic, and Power: the absolute value of myAUC - 0.5 multiplied by 2. Some other statistics are included as well such as average log2FC and the percent of cells expressing the gene in one cluster vs all other clusters.
With this being said, I would assume a myAUC score of 0.7 or above would imply the marker is effective. However given the formula used to calculate power, a myAUC score of 0.7 would correlate to a power of 0.4. So with this being said, would it be fair to assume that myAUC should be ignored for the purposes of validating markers? Or should both values be taken into account somehow?
Relevant answer
Answer
In the Seurat R package for analyzing single-cell RNA-seq data, "power" and "myAUC" are both functions used for selecting the most informative features or genes in the dataset. However, they employ different approaches and criteria to achieve this.
  1. Power: The "power" function in Seurat is used for identifying highly variable genes (HVGs) based on their expression dispersion relative to their mean expression level. This approach aims to capture genes that display biological variability across cells and are likely to be driving the observed heterogeneity in the dataset. By default, the "power" function calculates the power of a statistical test to detect differences in expression between two groups of cells, such as treatment vs. control or different cell types. It estimates the relationship between the mean expression and variance of each gene using a trend line and defines highly variable genes as those with expression levels deviating significantly from the trend line. The function outputs a list of highly variable genes ranked by their deviation.
  2. myAUC: The "myAUC" function in Seurat stands for "Area Under the Curve" and is used to rank genes based on their differential expression between two predefined groups or conditions. It employs the area under the receiver operating characteristic (ROC) curve as a measure of differential expression, where the ROC curve represents the true positive rate against the false positive rate at various gene expression thresholds. The myAUC algorithm evaluates the discriminatory power of each gene in distinguishing between the two groups and ranks them accordingly. Genes with higher AUC values have greater discriminatory power and are considered more differentially expressed between the groups of interest.
In summary, the "power" function identifies highly variable genes based on their expression dispersion relative to mean expression, while the "myAUC" function ranks genes based on their ability to discriminate between two predefined groups or conditions using the area under the ROC curve. Both functions aim to identify genes that are potentially important for distinguishing between different cell types, states, or experimental conditions, but they use different statistical and computational approaches to achieve this goal.
  • asked a question related to 3D
Question
4 answers
Every time results are coming differently for docking of RNA with a small molecule. Also, interaction reduces when energy minimization has been done(Avogrado, Chem 3D, Chem 3D ultra)
Please suggest what can I do about this.
Relevant answer
Answer
how to create protein Ensemble??? HADDOCK response is create an Ensemble for protein
  • asked a question related to 3D
Question
4 answers
Hi, I'm using DPM modeling for illustrating the flow mixing in a wavy microchannel. I can show 3D particle tracking, but I want to display particle distribution in 2D plane cross-sections. Does anyone know how to display particle distribution in different cross-sections (i.e., at sample 2D planes)?
Relevant answer
Answer
You can try this contours of DPM concentration on a surface https://www.cfd-online.com/Forums/fluent/45533-dpm-concentration.html
  • asked a question related to 3D
Question
12 answers
Can somebody please suggest the best tool to view, model and edit 3D protein structures at no cost?
Relevant answer
Answer
  • asked a question related to 3D
Question
2 answers
Dear all,
I'm having the following problem with importing I-deas Universal mesh file to Ansys Fluent: I have generated 3D mesh in Salome Meca, and when importing it to Ansys Fluent (in UNV format) it gives me an error which claims that I have tried to load 2D mesh into a 3D solver.
I wonder if anyone else has encountered a similar problem.
Here are a few figures about the export procedure.
Relevant answer
Answer
Hi Jarno
Is the mesh you made in I-deas software 3D? Or
2D? Maybe you just meshed the surface of the previous model?
  • asked a question related to 3D
Question
4 answers
I have 2D ERT data of six profiles, every second profile is taken nearly perpendicular to its preceding profile. Now I want to create a 3D grid of these profiles (I have coordinates and elevation data for each profile). If someone can help me do this I'll be grateful.
Relevant answer
Answer
To create a 3D grid from your 2D ERT data, you can use interpolation techniques to estimate the values of the subsurface properties between the profile lines. Here are the steps you can follow:
  1. Start by importing your ERT data into a suitable software package such as Surfer, Voxler, or Oasis Montaj.
  2. Define a grid for your 3D model. This will be based on the coordinates and elevation data for each profile. You can use the grid function in your software to create a regular or irregular grid.
  3. Interpolate the data between the profile lines. There are several interpolation techniques you can use such as kriging, inverse distance weighting (IDW), or radial basis functions (RBFs). These methods will estimate the values of the subsurface properties between the profile lines based on the known values at the profile locations.
  4. Once you have interpolated the data, you can visualize the 3D grid in your software package. This will allow you to explore the subsurface properties in 3D and identify any patterns or anomalies.
  5. Finally, you can export the 3D grid to a suitable format such as a raster or 3D surface file for further analysis or visualization.
It is important to note that the accuracy of your 3D model will depend on the quality and spacing of your ERT profiles, as well as the interpolation method you choose. It is also important to validate your model against other data sources such as borehole data to ensure the accuracy of your model.
  • asked a question related to 3D
Question
2 answers
I am looking for a journal (especially in forensic science or dental/medical imaging field) that allows the insertion of 3D files into its online published articles.
Relevant answer
Answer
All international journals support insertion of 3D images/videos as supplemental files in online versions which a reader can download to view. However, as for embedding the 3D file into the online doc itself is not supported because of its heavy size which probably slows down the doc viewer.
  • asked a question related to 3D
Question
5 answers
Hi,
I would like to apply a defined value of initial stress on 3D Shell elements in the initial step in Abaqus CAE. These shell elements are connected to a 3D Deformable Solid by a Tie Constrain. I have also tried to connect them through "shell-to-solid-coupling" constrain, but the same result. After the initial step, I provided a self-equilibrium step without any loading (Figure 4).
My problem is that after the next steps when loading starts a fast relaxation of this shell element (Figure 1) occurs without transferring the stresses to the tied 3D Solid shape (Figure 2). The tie properties are as shown in Figure 3.
My question is how to transfer a prestressing load (predefined field: stress) from a shell element to a 3D Solid, tied to each other since the main reason for this prestressing is to provide a negative deflection in the main structure?
Relevant answer
Answer
Aung Nyein Soe , your code is not correct and it is likely that your fortran compiler is not able to compile it. Indeed, according to Fortran 77 standards, all Fortran statements must be written in columns 7 to 72, which is not the case in your code (e.g. lines 20, 21 and 28).
Also, lines 56 to 61 do not make sense as you are trying to assign a value to an array, which is not possible for Fortran 77 (and also probably not what you want to do). The indexes of S11, S22... arrays are likely missing.
Before running an abaqus simulation, you should first try compiling your code to make sure no obvious programming mistake is present.
Charles
  • asked a question related to 3D
Question
2 answers
Any idea how to model (de novo) a large RNA sequence? The goal is to obtain a 3D coordinate file.
I tried popular software and also cant use HM approaches.
Relevant answer
Answer
Thank you, I'll try that.
  • asked a question related to 3D
Question
3 answers
Hello everyone! I have a question. How can I use segy in Matlab I need to add two dimension to 3D to get 5D?
Relevant answer
Answer
You can use the Matlab function "meshgrid()" to create a 5D grid. This function creates a set of matrices of equally spaced vectors which can be used to represent a 5D space. The syntax is as follows: [X1,X2,X3,X4,X5] = meshgrid(x1,x2,x3,x4,x5); where x1, x2, x3, x4, and x5 are vectors of equally spaced points in each of the 5 dimensions. For example, to create a 5D grid with 5 equally spaced points along each dimension you could use [X1,X2,X3,X4,X5] = meshgrid(-2:2,-2:2,-2:2,-2:2,-2:2) This will create a 5x5x5x5x5 grid of points in 5D space.
  • asked a question related to 3D
Question
5 answers
Identification and ranking of obstacles to the use of Metaverse in the academic system of the world What is your opinion on the impact of metaverse on universities? What obstacles do universities face in dealing with Metaverse? Metaverse, a 3D world, 3D university, virtual relations of education and learning in the Metaverse world, share your opinion with us, thank you. #metaverse #metaverse_univercity #keyhanefarda #keivanreisipourashraf
Relevant answer
Answer
The Metaverse can transform radically online distance higher education thanks to its affordances [1]. In an upcoming article about immersive learning design for the Metaverse [2], I too mention the ineffective digital twin campuses in virtual worlds and Second Life that Lilian Hupkens describes. This lack of agility and eventual strategic vision towards excellence in teaching and learning is one important obstacle for the effective adoption of the Metaverse in universities [3].
[1] Mystakidis, S. (2022). Metaverse in Online Distance Education: Superfluous or Inevitable? Innovating Higher Education Conference (I-HE2022). https://i-he2022.exordo.com/programme/presentation/76
[2] Mystakidis, S., & Lympouridis, V. (2023). Immersive Learning. Encyclopedia, 3(2), 396–405. https://doi.org/10.3390/encyclopedia3020026
[3] Mystakidis, S. (2022). Metaverse. Encyclopedia, 2(1), 486–497. https://doi.org/10.3390/encyclopedia2010031
Article Metaverse
  • asked a question related to 3D
Question
6 answers
I am doing 3D tissue culture. These black dots show up in my spheroids from time to time, please take a view of the picture below. Does anybody know about these black dots?
Relevant answer
Answer
We now know that these black dots are solid structures, potentially of crystalline nature. We still don't understand their origin, but believe that the medium and/or the agarose, on which the spheroids are formed, play a role.
  • asked a question related to 3D
Question
1 answer
Greetings, fellow researchers,
I am working on developing a new model for deep 3D face anti-spoofing, and I am reaching out to the research community to seek your help. My goal is to develop a model that can accurately distinguish between real and fake faces in various scenarios, using a range of attacks such as 3D masks, silicone masks, and mobile phone replays.
I have access to several datasets, including:
  1. 3D Mask Attack Dataset (3DMAD)
  2. Custom Silicone Mask Attack Dataset (CSMAD)
  3. Rapid-Rich Object Search Lab (ROSE)
  4. ERPA
  5. HKBU-MARs V1
  6. Replay-Mobile
  7. Wide Multi Channel Presentation Attack (WMCA)
  8. Wax Figure Face Database (WFFD)
I welcome any suggestions, feedback, or new ideas from the research community to make a novel contribution to the field of deep 3D face anti-spoofing.
Thank you for your attention and support.
Best regards,
MOHAMMED K. HUSSEIN
  • asked a question related to 3D
Question
2 answers
I am currently in research work of masonary structure.
I used DIANA Software for the analysis where i have to perform contact anlaysis to obtain the result.
I am a bit confused about setting the paramaters of the target element.
I referred to DIANA manual, but i couldnot figure out for 3D contact anlaysis.
So it would be grateful if anybody can help me in my project.
Thankyou.
Relevant answer
Answer
Upadesh Marahatta In DIANA software, performing contact analysis entails several stages, including describing the shape and mesh, configuring the contact parameters, and designating the load and boundary conditions. Here's a high-level summary of the procedure:
1. Establish the shape and mesh: Create a 3D model of the masonry building in DIANA program first. This may entail importing geometry from CAD tools or manually creating the model in DIANA. Create a mesh using the proper element classes and mesh density once the shape has been specified.
2. Configure the communication parameters: The Target Element Method is used in DIANA software for contact analysis. (TEM). This entails specifying the contact areas and setting up the specifications for the target element. Select the right contact element type (e.g., CONTA175) and define the target element's characteristics, such as contact stiffness, friction, and penetration depth.
3. Define the loading and boundary conditions: Next, specify the loading and border conditions for the study. This could entail imposing pressures, restrictions, or displacements on the model.
4. Once the model has been created, perform the study in DIANA software. This will produce data for the stone structure's contact pressures, stresses, and deformations.
It is essential to note that the precise factors and values for contact analysis will be determined by the masonry structure's application and geometry. Consult with experienced DIANA users or look for extra tools for assistance setting up contact analysis in DIANA software.
  • asked a question related to 3D
Question
1 answer
To date, I have only encountered academic literature pertaining to the Digital Image Correlation (DIG) of 2D or 3D smooth surfaces. Regrettably, I have yet to find any research publications regarding DIG analysis of rough surfaces.
Relevant answer
Answer
The Digital Image Correlation (DIC) technique is a powerful tool for analyzing the deformation and strain of a rough surface. GOM Correlate is a popular software package for analyzing DIC data. Here is a general procedure for using GOM Correlate to analyze a rough surface using DIC:
  1. Capture images of the surface: You will need to capture a series of images of the surface under investigation. The images should be taken from different angles and positions to ensure good coverage of the surface. You should also capture images of the surface before and after deformation or loading.
  2. Import images into GOM Correlate: Once you have captured the images, you will need to import them into GOM Correlate. You can do this by selecting "File" -> "Open Images" from the main menu.
  3. Define the region of interest (ROI): You will need to define the region of interest (ROI) in the images that you want to analyze. The ROI should cover the entire surface of interest. You can define the ROI using the "Region of Interest" tool in GOM Correlate.
  4. Apply pre-processing filters: Before analyzing the images, you may want to apply pre-processing filters to remove noise and enhance the contrast. GOM Correlate provides several pre-processing filters, such as Gaussian filtering, FFT filtering, and background subtraction.
  5. Set up the correlation parameters: You will need to set up the correlation parameters in GOM Correlate. This includes selecting the correlation algorithm, setting the search range, and defining the subset size.
  6. Compute the displacement and strain: Once the correlation parameters are set, you can compute the displacement and strain using GOM Correlate. GOM Correlate will generate displacement and strain maps for the surface under investigation.
  7. Analyze the results: You can analyze the displacement and strain maps to gain insights into the deformation behavior of the surface. You can also generate graphs and charts to visualize the results.
This general procedure should give you a good starting point for using GOM Correlate to analyze a rough surface using DIC. However, it is important to note that the exact procedure may vary depending on the specific surface and application being analyzed.
  • asked a question related to 3D
Question
2 answers
Dear colleagues,
It is commonly accepted that the total deflection Vt in a 4PB bending test consists of two parts: 1) Deflection Vb due to pure bending and 2) Deflection Vs due to shear forces. The last one doesn’t contribute to the occurring strain in the beam. Regarding the present devices and the dimensions of the beam, the ratio of Vs/Vb in the center of the beam for pseudo-static bending (up to 10 Hz) is given by: Vs/Vb = [4.(1+n).H2]/[As(3.L2 -4.A2)]. in which H is the height [m] and L is the effective length [m] of the beam; A is the distance between the outer and inner support (and not the distance between the two inner supports). For 99% of the present 4PB devices, A is equal to L/3 and thus in value equal to the parameter a which is used for the distance between the two inner supports. The parameter As is the so-called shear coefficient (in some papers denoted as β).
G.R. Cowper has done a lot of research work in determining a formula for the calculation of the shear coefficient (see Wikipedia “Timoshenko-Ehrenfest beam theory”). For the prismatic beam, Cowper gives the formula a = 10(1+n)/(12+11n) in which n is the Poisson ratio of the beam material. The formulas given in Wikipedia are all based on bending the object without touching or grabbing the beam. The theoretical approach to the problem is quite correct, but in reality, one has to touch the object to bend it. This touching (the point loads at the inner supports) has an influence on the value of the shear coefficient. For a prismatic beam, the shear coefficient according to Cowper is 0.8517. Using a 3D FEM model in which the beam was bent without touching it (a shear stress distribution at the inner supports was used for bending the beam) a value of 0,8588 was obtained. When the beam in the 3D FEM model was bent using line loads at the inner supports a value of 0.85 was calculated. In these calculations, the clamping forces were taken nil.
I use the value of 0.85 in processing 4PB data. Of course, I admit the influence of Vs is small but should not be ignored. And if the forces used for clamping the beam are too high this can also influence the value of the shear coefficient.
Relevant answer
Answer
Dear Mr. Delmonte,
By neglecting the influence of the shear forces the induced errors in the strain amplitude and the Smix figure are small. For IPC/COX/ASTM devices in which the effective length L of the beam is 355-356 mm and the height of the beam is 50 mm, the error is around 5% that is to say the Smix figure is underestimated by 5% and the strain amplitude is overestimated by 5%.
In other devices with bigger L figures (see 4PB platform) the error is less and dropped to around 3%. Thank you for your interest.
Best Regards
Ad Pronk
  • asked a question related to 3D
Question
1 answer
Hello. I’m a Civil Engineering student. Currently, I am doing my Master Thesis related with quality inspection. I would like to know how to check the leveling dots for plastering work on masonry walls by using Point cloud which means that “before the plastering work starts on site, we just need to do the leveling along the walls to make sure how much the plastering thickness should be for that wall. So, we need to check these plastering thickness dots which is leveling or not.” I am going to use 3D laser scanner and using MATLAB for programming. So, I would like to get some suggestions related with that issue. (You can see the below attached file as an example)
Relevant answer
Answer
To check the leveling dots for plastering work on masonry walls using a 3D laser scanner and MATLAB, you can follow these general steps:
  1. Acquire a point cloud of the wall: Use the 3D laser scanner to capture a point cloud of the masonry wall, including the leveling dots.
  2. Import the point cloud into MATLAB: Use MATLAB's point cloud processing tools to import the point cloud data into MATLAB.
  3. Segment the point cloud: Use MATLAB's point cloud processing tools to segment the point cloud data and extract only the points corresponding to the leveling dots.
  4. Estimate the surface of the wall: Use MATLAB's point cloud processing tools to estimate the surface of the wall based on the remaining points in the point cloud.
  5. Compare the leveling dots to the estimated wall surface: Use MATLAB to calculate the distance between each leveling dot and the estimated surface of the wall. If the distance is within a certain tolerance, the leveling dot is considered to be level.
  6. Visualize the results: Use MATLAB's visualization tools to create a 3D model of the wall and the leveling dots, with color coding to indicate which dots are level and which are not.
  7. Adjust the plaster thickness: Use the information from the analysis to adjust the plaster thickness as needed to ensure a level finish.
Here are some specific suggestions for each of these steps:
  1. Acquire a point cloud of the wall: Ensure that the laser scanner is positioned correctly and that the entire wall is scanned, including the leveling dots. Use a high-quality scanner to ensure accurate data capture.
  2. Import the point cloud into MATLAB: Use MATLAB's pointCloud function to import the point cloud data into MATLAB.
  3. Segment the point cloud: Use MATLAB's findNeighborsInRadius function to identify the points corresponding to the leveling dots, based on their known locations.
  4. Estimate the surface of the wall: Use MATLAB's pcfitplane function to estimate the surface of the wall based on the remaining points in the point cloud.
  5. Compare the leveling dots to the estimated wall surface: Use MATLAB's pdist2 function to calculate the distance between each leveling dot and the estimated surface of the wall. Choose a tolerance level that is appropriate for your application.
  6. Visualize the results: Use MATLAB's plot3 function to create a 3D model of the wall and the leveling dots, with color coding to indicate which dots are level and which are not. You may also want to use MATLAB's patch function to create a 3D mesh representation of the wall surface.
  7. Adjust the plaster thickness: Use the information from the analysis to adjust the plaster thickness as needed to ensure a level finish. This may involve additional iterations of scanning and analysis, depending on the complexity of the wall geometry and the required level of accuracy.
Hope it helps
  • asked a question related to 3D
Question
1 answer
Of course, nowadays organogenesis of full developed arms and legs is still a fantasy, but knowing that limbs are a extremely complex system, the cost of making one would be astronomical. So, do we actually need 3D bioprinting for the creation of limbs when other methods are way more developed and probably cheaper?
Relevant answer
Answer
Hi Edgardo,
This is a very interesting question! I agree, that limbs are incredibly complex, therefore 3D printing the entire structure is not feasible right now. However bioprinting may still be useful for printing certain parts of the limb, such as articular cartilage caps. Bioprinting may also be useful for 3D organoid culture. Mesenchymal progenitors can be encapsulated in a bioink like GelMA and printed into 3D structures and differentiated into limb forming units. Here's a good paper that outlines sone techniques!
  • asked a question related to 3D
Question
2 answers
Hi, any experienced person here for A-solver in cst?
I need some initial help to start working with A-solver. does it can generate 3D farfield results?
Relevant answer
Answer
Thanks Miguel.
I could run a simulation with A solver but it doesn’t support lossy dielectrics which was important in my simulation
  • asked a question related to 3D
Question
2 answers
I need the data for experiments of super-resolution. That is, low-resolution data can be get by convoluted Ricker wavelet with low-frequency, high-resolution data can be get by convoluted Ricker wavelet with high-frequency.
Relevant answer
Answer
Generating 3D synthetic seismic data involves simulating the reflection and transmission of seismic waves in a subsurface model. Here are the general steps for creating 3D synthetic seismic data:
  1. Create a subsurface model: The subsurface model should represent the geological features of the subsurface, such as the location and geometry of geological formations, faults, and other structures. The model can be created using geological data, such as well logs, seismic data, and geologic maps.
  2. Assign rock properties: Each layer of the subsurface model should be assigned appropriate rock properties, such as density, compressional wave velocity, and shear wave velocity. These properties can be estimated using well logs and other geological data.
  3. Generate a seismic source: A seismic source is used to generate seismic waves that travel through the subsurface model. The source can be a single point source, a linear source, or an array of sources.
  4. Simulate wave propagation: The seismic waves generated by the source propagate through the subsurface model, reflecting and refracting at each layer boundary based on the rock properties of each layer.
  5. Record seismic data: Seismic data is recorded at the surface or in boreholes as the seismic waves are reflected and refracted back to the surface. The recorded data can be used to create 3D seismic images of the subsurface.
There are several software tools available for generating 3D synthetic seismic data, such as Petrel, GeoSynthetics, and OpenSees. These tools provide a user-friendly interface to create subsurface models and simulate wave propagation to generate synthetic seismic data. However, creating accurate 3D synthetic seismic data requires careful consideration of geological data, rock properties, and modeling assumptions.
  • asked a question related to 3D
Question
1 answer
Would anyone know how to answer this question? Or let me know which supplements are really needed at this stage of building the 3D skin?
Relevant answer
Answer
Maria Victória Souto Cholera toxin is often utilized as a supplement in 3D skin maintenance medium to stimulate keratinocyte differentiation and skin structure maintenance. The B-subunit of cholera toxin (CTB) binds to cell surface gangliosides and may permeate the stratum corneum of the skin, enabling its topical application as an adjuvant in vaccines.
While cholera toxin is widely utilized in 3D skin models, it is not required, and other additives can be used instead. For example, in the absence of cholera toxin, several studies have employed retinoids or transforming growth factor-beta (TGF-beta) as a supplement to preserve skin differentiation.
The use of cholera toxin in 3D skin models might generate issues regarding toxicity and immune response. The use of CTB-conjugated cholera toxin can alleviate these concerns since CTB is low in toxicity and induces a tolerogenic immune response.
In conclusion, while cholera toxin is a frequent supplement used in 3D skin models, it is not required, and alternate supplements such as retinoids or TGF-beta can be used instead. CTB-conjugated cholera toxin may be a safer option than unmodified cholera toxin. The supplements used will be determined by the specific study questions and the desired qualities of the 3D skin model.
  • asked a question related to 3D
Question
1 answer
My group and I are currently working on reducing nasal necrosis in premature infants due to the pressure of nasal prongs on the septum. For the testing of our prototype, we will need a premature infant nose throat-model to perform pressure and stress calculations.
I would be very grateful if anyone could send me 3D files of this model or even point me in the right direction of where to go.
Thank you for any and all assistance.
Elizabeth Rhodes
Relevant answer
Answer
Elizabeth Rhodes Such models may be found in a variety of resources and internet archives. Here are a few recommendations:
The NIH 3D Print Exchange is a public database of 3D models that may be produced using a 3D printer. They include a section dedicated to medical models, including human anatomy models. You might look for "premature newborn nose throat-model" to check if any relevant models are available for download.
GrabCAD is a user-generated platform where engineers and designers may exchange their 3D models. They include a section dedicated to medical models, including human anatomy models. You might look for "premature newborn nose throat-model" to check if any relevant models are available for download.
  • asked a question related to 3D
Question
2 answers
I am simulating the crimping of a stent in ABAQUS/Standard using a 3D deformable cylinder on which I impose a displacement in order to crimp the stent from an initial diameter of 2.5 mm to a final 1 mm.
After doing the simulation I'm interested in obtaining the radial strength. According to FDA, the radial strength is the pressure at which a stent experiences irrecoverable deformation. So the idea is to plot this pressure (y-axis) with respect to the strain or radial displacement(x-axis).
Do you have any suggestion?
Relevant answer
Answer
Hi, if you find the solution to your problem, would you please share it here?
I have the same issue too, I need to obtain the radial force.
  • asked a question related to 3D
Question
3 answers
Hello Researchers!
I am looking for the Manual of FLAC 3D version 6.0 because there are some changes regarding the codes between versions 5.0, 6.0, and 7.0. Is it anybody who can drop a file or a link about this?
Any responses will be appreciated. Thank you.
Regards.
Relevant answer
Answer
Hi Ahmad,
If you have installed version 6 already,
1. you will find the documentation under the directory where you installed the software. It would be entitled "FLAC3D 6.0 Help".
2. Open the software and choose the "Help" menu. For the dynamic analysis, follow the path FLAC3D modeling--problem solving--scroll to the end--dynamic analysis.
  • asked a question related to 3D
Question
5 answers
Dear all,
Any idea about 3D space syntax tool?
Relevant answer
Answer
Seyedeh Masoumeh Abtahi is depth map work on 3D level?
  • asked a question related to 3D
Question
3 answers
Dear all,
I am simulating swirl methane flame by employing ANSYS Fluent. Complete simulation with 3D mesh consuming much time, thus, is it possible to get the final solution by feeding a velocity profile corresponding to non reacting flow (cold flow) obtained at burner exit using 3D mesh as a inlet BC to inlet of outer domain which is of 2D mesh?
In short: 3D mesh is used to obtain velocity profile at the burner exit. Can we feed this velocity profile to 2D mesh based outer domain (combustor) as a inlet BC to get the final solution?
Relevant answer
Answer
Supriya Naik Thank you for your Answer
  • asked a question related to 3D
Question
2 answers
What are the sources to draw 3D image of our device formed by FDTD because when we extract image from FDTD, it is not too much good effects.
Relevant answer
Answer
I'm not sure what you mean. Do you want to visualise (in 3D) the fields calculated by FDTD that are inside your structure?
For 3D visualisation, I find that Paraview is useful software, and it is free. However, it is not always simple to import your data into it if your simulation software does not save in a suitable format.