Science topic
Laboratory - Science topic
A laboratory is a facility that provides controlled conditions in which scientific research, experiments, and measurement may be performed.
Questions related to Laboratory
Literature on the above subject will be welcomed
Today, I found that our following Preprint PDF is available on ResearchGate
Potential Lithium Sedimentary Deposits of the Land and Deep Oceans
January 2024
DOI: 10.20944/preprints202312.0073.v2
LicenseCC BY 4.0
Lab: V. Balaram's Lab
V. Balaram, John S. Armstrong-AltrinRiyaz M. KhanB. Srinivasa Rao
This manuscript was rejected by Minerals
Minerals deleted it already
We are in the process of communicating with other journals
This Preprint on ResearchGate is creating problems for us when we communicate this manuscript to any other journals
Since the preprint is available online, our manuscript is not passing through the Similarity Test.
Hence, I request you to kindly delete the above preprint PDF from ResearchGate and help us publish this manuscript in a Good Journal
Regards
V. Balaram
We are an R&D laboratory focused on anionic, cationic, and zwitterionic surfactants and usually tackle surfactant synthesis and analysis of products from customers. In particular, we deal with AOS (alpha-olefin sulfonates), primary alcohol sulfates, betaines, amphoacetates, amine-oxides.. etc. To gear our analytical laboratory up, we identified an HPLC-MS (single quadrupole) instrument as a valuable addition to comply with unmet needs that have risen in the last years, like figuring out the outcome of the new reaction and investigating byproducts and new raw materials. Currently, we are evaluating three choices: Agilent LC/MSD, Waters Acquity Arc System (with Qa Acquity Detector), and Shimadzu LC-MS2050. Could anyone in this field share their experiences with these instruments? and suggest which of them is the most reliable for this application. Thank you so much for your attention and participation.
This question needed to be answered to a civil engineering student studying his first year right now.
Hello everyone,
I have a monoclinic C2 space group single crystal sample glued to a tenon plate. I know the surface normal direction and the edge plan of the crystal. Also, I know the XY plane of the tenon plate. How can I get the Euler angles to relate the frames of the sample and the tenon plate (Lab frame)?
Any article or suggestion on how to go about this problem will be much appreciated. Thanks in advance
(I have also attached a picture of the crystal on the plate. The circle in the picture marks the surface normal direction (1 0 -2) and the edge plane is (0 1 0). The blue vectors represent the frame of the tenon plate)
In the journal, "THE TRANSITION FROM GEL SEPARATORY SERUM TUBES TO LITHIUM HEPARIN GEL TUBES IN THE CLINICAL LABORATORY" by Oğuzhan Zengi, In what ways does the use of LIH tubes impact laboratory workload and efficiency compared to traditional serum tubes, especially considering the potential benefits of reduced aspiration errors and false results?
A colleague is seeking a laboratory to conduct Cryptococcus immunohistochemistry on formalin-fixed, paraffin-embedded cat tissues. Cryptococcus-compatible structures were observed within lesions, and a special stain was performed; however, she seeks definitive confirmation through immunohistochemistry to enhance the report.
Based on the conclusion of the article entitled, "Red and white blood cell morphology characterization and hands-on time analysis by the digital cell imaging analyzer DI-60" DI-60 may contribute to the improvement of laboratory efficiency with increased feasibility. However, for abnormal samples, it should be utilized carefully with other indicators such as CBCs and flags from the hematology analyzer. Caution is also required when reporting the borderline results of RBC morphologies considering the imprecision of DI-60. With that being said, I want to know other analyzers which can cater the demand for an accurate and precise detection both from abnormal and normal cases, especially since working in the laboratory means encountering more abnormal cases.
Is there any Neuroscience Lab PI from any American university here? i want to know about their research work
According to Sundareshan and Khardori (2019), "The expectation is that antibiotic resistance can be prevented through the genotypic identification of bacteria and their antibiotic-resistance genes in the diagnostic microbiology laboratory. Clinical studies are still required to validate the genotypic approach to antimicrobial susceptibility testing." How do we validate DNA-based assays for antimicrobial susceptibility testing? How do we know if the approach is effective for the detection of bacteria and bacterial resistance genes?
According to the journal presented by Neuwinger, Büschenfelde, and Kappert (2019), lactate dehydrogenase activity can falsely increase because of underfilling the blood specimen tube. Stated in the discussion part, "test results obtained in underfilled blood tubes should be communicated by the diagnostic laboratory with an attached comment pointing to the possibility of a falsely elevated test result". My question is derived from the mentioned part of the journal:
Should a medical laboratory scientist be in the situation of underfilling a blood specimen, what proper solution or protocol must be applied? Would the researcher's recommendation suffice?
We would like to buy a new cell counting device for our Lab, and we're searching for a device, with a reasonable price. However, we're not sure about the reliability and the reproducibility of the results using different devices, including Logos LUNA II, Thermofisher Countess II, Biorad TC20, etc.
personally, I've used LUNA II with their 2-chamber slides and I was happy with the repeatability. Also I've used Countess II with reusable slides which was not a satisfactory experience. But I can't make a decision between the two as they were not both with single-use chamber slides.
I would appreciate if anyone can provide a head-to-head comparison, or device-to-hemocytometer comparison, or at least share their device reliability experience?
Many thanks.
A Vacancy of Sr Scientist
Duration: 12 months
Location: Bethesda, MD/USA
Job Description:
Contribute to the generation of stable cell lines for vaccine and therapeutic protein candidates including monoclonal antibodies, recombinant proteins, and virus-like particles.
Independently execute each step of the cell line development process including plasmid production, transfection, single cell cloning, clone expansion in static culture plates and shake flasks, fed-batch analysis, and clone stability studies.
Use automated platforms for clone selection and screening.
Prepare plasmid DNA using standard molecular cloning techniques.
Participate in cell line development platform design, optimization, and cycle-time reduction studies including methods for clone selection, expansion, ranking, and characterization.
Perform small-scale process development studies using various culture vessels including tissue culture plates, shake flasks, and small-scale bioreactors.
Generate stable pools and perform transient protein production for supply of reagent-grade material.
Provide laboratory support for medium preparation and ordering of supplies.
Perform maintenance of cell counters and bioprocess analyzers, coordination of service visits, and regular ordering of consumables.
Train other laboratory personnel on use of equipment and corresponding processes.
Write and review technical reports documenting process development studies and stable cell line generation work.
Work with other team members to generate experimental plans for process development studies.
Write and review standard operating procedures for cell line development processes and instrumentation.
Maintain complete documentation records, including a detailed and up-to-date laboratory notebook, to support regulatory filings.
Regularly communicate progress to team lead and present work to cell line development team .
Experience Required
B.S. in Biological Sciences with a minimum of 5 years of relevant work experience or M.S. in Biological Sciences with independent research experience in an academic or industrial setting.
Hands-on experience with aseptic technique and mammalian cell culture along with supporting technologies for cell line engineering including cell counting, high-throughput transfection, single-cell cloning, and flow cytometry.
Experience in preparing technical reports, standard operating procedures, and data presentations.
Ability to work independently to execute defined experiments and troubleshoot issues as needed to meet project timelines.
Ability to effectively communicate plans, results, challenges, and ideas to other team members in oral and written forms.
Familiarity with computer software for word processing and data analysis.
Experience in monoclonal antibody and/or vaccine production.
Kindly send me your resume in Word format
Earliest availability for the assignment:
Earliest availability for the Interview:
Current location:
Are you ready to relocate?
Preferred contact number.
If you know anyone who would be interested, please, let me know.
In the research paper "The transition from gel separatory serum tubes to lithium heparin gel tubes in the clinical laboratory," what were the main factors considered in evaluating the impact of the transition on laboratory operations, and how were they assessed?
This question is directed on the performance of the Sysmex DI-60 digital morphology analyzer and its contributions on the improvement in the laboratory workflow. I am curious as to what capabilities of the analyzer could potentially reduce the long TAT and tedious process of performing manual methods which may possibly eliminate/lessen the need to perform manual methods.
I am trying to do a reduction reaction of 4-Hydroxybenzophenone using TiCl4/Zn. Can anyone suggest me which form of TiCl4 (for example Titanium(IV) chloride, 1M soln. in dichloromethane, Titanium(IV) chloride, 99.99% (metals basis), Titanium(IV) chloride, 99.9%) is ideal for this reaction in laboratory scale.
Thank you
What are the laboratory procedures for identifying the concentrations of formic acid and acetic acid in aqueous solutions using titration, spectrophotometry, or gas chromatography methods (excluding HPLC and IC methods)?
Oguzhan Zhengi, the sole author of the journal entitled “The Transition from Gel Separatory Serum Tubes to Lithium Heparin Gel Tubes in the Clinical Laboratory”, stated that a specific criteria was adhered to when handling the specimens. Throughout the Methodology, Zhengi explained the Clinical and Laboratory Standards Institute (CLSI) Criteria - GP34-A:2010. What was the content of this specific criteria and how did he utilize this document?
Campolestis chloridae, a parasitoid with promising implications for insect pest management, is the focus of our current research project. We are seeking expertise in rearing this species to further our investigations.
We are looking for its nucleus culture if available anywhere in India or Abroad or its incidence so that we can get field collected larvae or cocoons to initiate its Culturing.
Our laboratory is equipped with standard insect rearing facilities. However, we are encountering challenges specific to Campolestis chloridae and would appreciate insights from researchers with direct experience.
Contributing to this research project offers the opportunity to advance our understanding of parasitoid biology and its applications in pest management. Collaboration could lead to joint publications and further opportunities for research in this field.
Suggestions are kindly invited.
I'm eager to gain further insights into the Sysmex DI-60, particularly its relevance and importance in the clinical laboratory.
Polymerase Chain Reaction (PCR) testing is a molecular biology technique used to amplify and analyze DNA or RNA samples. So, To perform PCR testing, which list of laboratory apparatus and equipment is required?
What is a phenomenon called "false vacuum collapse"?
as you know :
Mean field energy and bubble formation. The cloud is initially prepared in FV with all atoms in |↑⟩ (A). Although the single spin mode |↓⟩ is lower in energy in the center of the cloud (E↓E↑), the opposite is true in the low-density tails. The interface (domain wall) between ferromagnetic regions with opposite magnetism has positive (kinetic) energy, which is added to the minimum double energy resulting from ferromagnetic interaction. Macroscopic tunneling can occur resonantly in the bubble mode (B), which has a |↓⟩ bubble in the center. The increase in core energy compensates for the cost of domain-wall energy. Crossing the barrier can be caused by quantum fluctuations at zero temperature (full arrow) or by thermal fluctuations at finite temperature (empty arrow). After the tunneling process, the bubble size increases in the presence of dissipation to reach the true vacuum (TV) state (C), without returning to (A). Credit: Nature Physics (2024). DOI: 10.1038/s41567-023-02345-4
An experiment carried out in Italy with theoretical support from the University of Newcastle provided the first experimental evidence of vacuum decay.
In quantum field theory, when a not-so-stable state becomes a true stable state, it is called a "pseudovacuum collapse." This happens through the creation of small local bubbles. While existing theoretical work can predict how often this bubble formation occurs, there is not much empirical evidence.
The Pitaevskii Center for Supercold Atoms Laboratory for the Bose-Einstein Condensation in Trento reports for the first time observations of phenomena related to the stability of our universe. The results are the result of a collaboration between the University of Newcastle, the National Institute of Optics CNR, the Department of Physics at the University of Trento and TIFFA-INFEN and are published in Nature Physics.
The results are supported by theoretical simulations and numerical models, confirming the origin of the decay quantum field and its thermal activation, and opening the way to simulate out-of-equilibrium quantum field phenomena in atomic systems.
This experiment uses a supercooled gas at a temperature less than one microkelvin from absolute zero. At this temperature, the bubbles appear as the vacuum collapses, and Newcastle University's Professor Ian Moss and Dr Tom Billam were able to conclusively show that the bubbles are the result of heat-activated vacuum collapse.
Ian Moss, Professor of Theoretical Cosmology at Newcastle University's School of Mathematics, Statistics and Physics, said: "Vacuum collapse is thought to play a central role in the creation of space, time and matter in the Big Bang, but so far it has not. In particle physics, the decay of the Higgs boson vacuum changes the laws of physics and creates what has been described as the 'ultimate ecological catastrophe'."
Dr Tom Bilam, Senior Lecturer in Applied/Quantum Mathematics, added: "Using the power of ultracold atom experiments to simulate analogues of quantum physics in other systems – in this case the early universe itself – is a very exciting area of research. the moment."
This research opens new avenues in understanding the early universe as well as ferromagnetic quantum phase transitions.
This groundbreaking experiment is only the first step in the discovery of vacuum decay. The ultimate goal is to find vacuum decay at absolute zero temperature, where the process is driven solely by quantum vacuum fluctuations. An experiment in Cambridge, supported by Newcastle as part of the national QSimFP collaboration, is doing just that.
Stam Nicolis added a reply:
Just what the name says: There are many physical systems, whose potential energy, in the absence of fluctuations, possesses more than one minima. If these minima are not degenerate, it can occur that one is the absolute minimum, however, due to the choice of initial conditions, the system is found in another minimum. In the absence of fluctuations, it will stay in the potential well of that minimum.
In the presence of fluctuations, it can occur that the relative minimum is no longer a minimum: In that case the system won't stay there forever and it is possible to compute the rate at which it will evolve to another state.
While the presence of fluctuations is a necessary condition, it isn't sufficient for transitions to be possible.
Sergey Shevchenko added a reply:
“What is a phenomenon called "false vacuum collapse"?”
- the answer to this question is: the question really is absurdity, since really there cannot be fundamentally any “false vacuum”, i.e. that really is an fundamental absurdity, and so its “collapse” is absurdity as well.
Though yeah, in mainstream physics really rather numerous fantastic/mystic “true/false vacuums” really exist, and corresponding publications, where corresponding fantastic/mystic properties and effects of/in the vacuums are “discovered”, are well popular and numerous.
That exists in the mainstream completely logically inevitably from the fact that in the mainstream all really fundamental phenomena/notions, first of all on this case “Matter”– and so everything in Matter, i.e. “particles”, “fundamental Nature forces” – and so “fields”, etc., including “vacuum”, “Consciousness”, “Space”, “Time”, “Energy”, “Information”, are fundamentally completely transcendent/uncertain/irrational,
- and so in every case when the mainstream addresses to something that is really fundamental, the results completely inevitably are only some the fantasies.
More see recent SS post in https://www.researchgate.net/post/What_is_a_super_vacuum_Is_the_earth_in_a_vacuum_And_what_is_dark_energy , and links in the post; reDzennn comment, 9/8 [because of too active moderator] passages, to a Nature Physics (2024) paper in
https://phys.org/news/2024-01-phenomenon-false-vacuum-decay.html) directly relates to the thread question.
Zoltan Vilagosh added a reply:
Not that complicated really. False vacuum example = because you cannot see over the hill, you think are at the lowest level possible. This makes you think you have no potential energy left. But a surprise awaits if you make it to the top of the hill...you tumble lower onto the vast endless plain on the other side.
__/\O/\
\
\__O
Sergey Shevchenko added a reply:
“…Not that complicated really. False vacuum example = because you cannot see over the hill, you think are at the lowest level possible. This makes you think you have no potential energy left. But a surprise awaits if you make it to the top of the hill...you tumble lower onto the vast endless plain on the other side. …..”
- that above looks as tooo not complicated passage really, though, again, on such level the authors of the paper in a top physical Nature Physics (2024) journal also thought,
- which “discovered” “false vacuum bubbles decays” in some Bose-Einstein Cond sate of Na-23 atoms, more see reDzennn comment, 8 passages, in https://phys.org/news/2024-01-phenomenon-false-vacuum-decay.html, the strangely removed by moderator passage is in the end of whole comments series.
Though yeah, the really full stop “false vacuum” theories are rather popular in mainstream physics, including rather popular is the theory that Matter was created soon 14 billion years ago at some “bubble in spacetime decay”. Thank heavens till now no any even small bubbles didn’t decay near Earth, and nowhere in Space at all, in last 10 billion of years Milky Way existence.
However, again, this full stop – and so quite easily composed - fantasies are so rather popular, and in this case so some people don’t like the comment, correspondingly it is heavily “down voted”.
Juan Weisz added a reply
Perhaps vacuum does not collapse,
but you know the saying, nature abhors vacuum.
Harri Shore added a reply
False vacuum collapse is a theoretical concept in particle physics and cosmology. It suggests that our universe might currently exist in a metastable vacuum state, also known as a false vacuum. If this false vacuum were to collapse to a lower energy state, it could trigger catastrophic consequences, such as the destruction of all matter and the laws of physics as we know them. This hypothetical scenario is based on certain models in quantum field theory and the structure of the universe. However, there is currently no empirical evidence to support the occurrence of false vacuum collapse.
Harri Shore added a reply:
The "false vacuum collapse" refers to a hypothetical cosmic event that could have catastrophic implications for the universe as we know it. In theoretical physics, a vacuum state is considered to be the lowest possible energy state in which a quantum field can exist. A "true vacuum" is the absolute lowest energy state, while a "false vacuum" is a local minimum that is not the absolute lowest. The concept of a false vacuum collapse is based on the idea that if our universe currently exists in a false vacuum state, it is not truly stable but only metastable. This means there's a possibility, however minute, that a transition could occur, causing the universe to "fall" into the true vacuum state. Such a transition would propagate through space at the speed of light and fundamentally alter the laws of physics, potentially obliterating all structures in the universe as it goes.This transition could be triggered spontaneously due to quantum fluctuations or by a high-energy event. Once started, it would create a bubble of true vacuum that expands in all directions, converting the false vacuum into the true vacuum.Despite its dramatic implications, it's important to note that this is a highly speculative hypothesis and currently there is no experimental evidence to suggest that our universe is in a false vacuum state. Additionally, even if it were true, the odds of such an event happening within our lifetimes—or within the lifespan of the universe as it has existed so far—are exceedingly low.
What is a phenomenon called "false vacuum collapse"?
as you know :
Mean field energy and bubble formation. The cloud is initially prepared in FV with all atoms in |↑⟩ (A). Although the single spin mode |↓⟩ is lower in energy in the center of the cloud (E↓E↑), the opposite is true in the low-density tails. The interface (domain wall) between ferromagnetic regions with opposite magnetism has positive (kinetic) energy, which is added to the minimum double energy resulting from ferromagnetic interaction. Macroscopic tunneling can occur resonantly in the bubble mode (B), which has a |↓⟩ bubble in the center. The increase in core energy compensates for the cost of domain-wall energy. Crossing the barrier can be caused by quantum fluctuations at zero temperature (full arrow) or by thermal fluctuations at finite temperature (empty arrow). After the tunneling process, the bubble size increases in the presence of dissipation to reach the true vacuum (TV) state (C), without returning to (A). Credit: Nature Physics (2024). DOI: 10.1038/s41567-023-02345-4
An experiment carried out in Italy with theoretical support from the University of Newcastle provided the first experimental evidence of vacuum decay.
In quantum field theory, when a not-so-stable state becomes a true stable state, it is called a "pseudovacuum collapse." This happens through the creation of small local bubbles. While existing theoretical work can predict how often this bubble formation occurs, there is not much empirical evidence.
The Pitaevskii Center for Supercold Atoms Laboratory for the Bose-Einstein Condensation in Trento reports for the first time observations of phenomena related to the stability of our universe. The results are the result of a collaboration between the University of Newcastle, the National Institute of Optics CNR, the Department of Physics at the University of Trento and TIFFA-INFEN and are published in Nature Physics.
The results are supported by theoretical simulations and numerical models, confirming the origin of the decay quantum field and its thermal activation, and opening the way to simulate out-of-equilibrium quantum field phenomena in atomic systems.
This experiment uses a supercooled gas at a temperature less than one microkelvin from absolute zero. At this temperature, the bubbles appear as the vacuum collapses, and Newcastle University's Professor Ian Moss and Dr Tom Billam were able to conclusively show that the bubbles are the result of heat-activated vacuum collapse.
Ian Moss, Professor of Theoretical Cosmology at Newcastle University's School of Mathematics, Statistics and Physics, said: "Vacuum collapse is thought to play a central role in the creation of space, time and matter in the Big Bang, but so far it has not. In particle physics, the decay of the Higgs boson vacuum changes the laws of physics and creates what has been described as the 'ultimate ecological catastrophe'."
Dr Tom Bilam, Senior Lecturer in Applied/Quantum Mathematics, added: "Using the power of ultracold atom experiments to simulate analogues of quantum physics in other systems – in this case the early universe itself – is a very exciting area of research. the moment."
This research opens new avenues in understanding the early universe as well as ferromagnetic quantum phase transitions.
This groundbreaking experiment is only the first step in the discovery of vacuum decay. The ultimate goal is to find vacuum decay at absolute zero temperature, where the process is driven solely by quantum vacuum fluctuations. An experiment in Cambridge, supported by Newcastle as part of the national QSimFP collaboration, is doing just that.
Stam Nicolis added a reply:
Just what the name says: There are many physical systems, whose potential energy, in the absence of fluctuations, possesses more than one minima. If these minima are not degenerate, it can occur that one is the absolute minimum, however, due to the choice of initial conditions, the system is found in another minimum. In the absence of fluctuations, it will stay in the potential well of that minimum.
In the presence of fluctuations, it can occur that the relative minimum is no longer a minimum: In that case the system won't stay there forever and it is possible to compute the rate at which it will evolve to another state.
While the presence of fluctuations is a necessary condition, it isn't sufficient for transitions to be possible.
Sergey Shevchenko added a reply:
“What is a phenomenon called "false vacuum collapse"?”
- the answer to this question is: the question really is absurdity, since really there cannot be fundamentally any “false vacuum”, i.e. that really is an fundamental absurdity, and so its “collapse” is absurdity as well.
Though yeah, in mainstream physics really rather numerous fantastic/mystic “true/false vacuums” really exist, and corresponding publications, where corresponding fantastic/mystic properties and effects of/in the vacuums are “discovered”, are well popular and numerous.
That exists in the mainstream completely logically inevitably from the fact that in the mainstream all really fundamental phenomena/notions, first of all on this case “Matter”– and so everything in Matter, i.e. “particles”, “fundamental Nature forces” – and so “fields”, etc., including “vacuum”, “Consciousness”, “Space”, “Time”, “Energy”, “Information”, are fundamentally completely transcendent/uncertain/irrational,
- and so in every case when the mainstream addresses to something that is really fundamental, the results completely inevitably are only some the fantasies.
More see recent SS post in https://www.researchgate.net/post/What_is_a_super_vacuum_Is_the_earth_in_a_vacuum_And_what_is_dark_energy , and links in the post; reDzennn comment, 9/8 [because of too active moderator] passages, to a Nature Physics (2024) paper in
https://phys.org/news/2024-01-phenomenon-false-vacuum-decay.html) directly relates to the thread question.
Zoltan Vilagosh added a reply:
Not that complicated really. False vacuum example = because you cannot see over the hill, you think are at the lowest level possible. This makes you think you have no potential energy left. But a surprise awaits if you make it to the top of the hill...you tumble lower onto the vast endless plain on the other side.
__/\O/\
\
\__O
Sergey Shevchenko added a reply:
“…Not that complicated really. False vacuum example = because you cannot see over the hill, you think are at the lowest level possible. This makes you think you have no potential energy left. But a surprise awaits if you make it to the top of the hill...you tumble lower onto the vast endless plain on the other side. …..”
- that above looks as tooo not complicated passage really, though, again, on such level the authors of the paper in a top physical Nature Physics (2024) journal also thought,
- which “discovered” “false vacuum bubbles decays” in some Bose-Einstein Cond sate of Na-23 atoms, more see reDzennn comment, 8 passages, in https://phys.org/news/2024-01-phenomenon-false-vacuum-decay.html, the strangely removed by moderator passage is in the end of whole comments series.
Though yeah, the really full stop “false vacuum” theories are rather popular in mainstream physics, including rather popular is the theory that Matter was created soon 14 billion years ago at some “bubble in spacetime decay”. Thank heavens till now no any even small bubbles didn’t decay near Earth, and nowhere in Space at all, in last 10 billion of years Milky Way existence.
However, again, this full stop – and so quite easily composed - fantasies are so rather popular, and in this case so some people don’t like the comment, correspondingly it is heavily “down voted”.
Hello, what is the correct way to express the biomass results measured with a laboratory digital scale? Most scientific works express it as weight, however very few express it as mass,
thank you very much
Providers should make an effort to understand local resistance patterns including those of the referring hospitals. Such data are relevant to monitor longitudinal resistance trends and formulate regional public health interventions. The institutional antibiograms often contained insufficient isolates and multidrug resistant isolates were not routinely tested.
Dear Forum Members,
I hope this message finds you well. I am currently considering the purchase of a Q-TOF LCMS-9030 Mass Spectrometer for my laboratory, and I would greatly appreciate hearing from anyone who has experience working with this instrument.
If you have used the Q-TOF LCMS-9030, I would be interested in hearing your thoughts and experiences. Specifically, I am seeking reviews on the instrument's performance, reliability, user-friendliness, and any limitations or challenges you may have encountered.
Your insights will be incredibly valuable in helping me make an informed decision about this purchase. Thank you in advance for sharing your expertise and feedback.
Best regards.
Sometimes when I touch my colleague or metal bodies. i fell shock with some minor electric sound.
I want to determine the coal density at the laboratory for reserve estimation. Please help me by providing the most appropriate materials and methods.
I need to order an ATP Assay Kit for my work, and I found this kit on the BT Lab website. Has anyone tried the kits from this site? Because this is the first time I will order from them.
For a person whose name is the only one listed on an article that was produced in a laboratory or institution containing several researchers who contributed to the publication of this article:
does this mean that this person is a "genius" and was able to publish alone?
Or does it mean that they lack the spirit and understanding of teamwork and the courage to acknowledge other members of the laboratory?
We are using some enzymes to test in the laboratory. Trying to figure out the best method treat the waste water. The actual chemical we using are testing with enzyme based drain cleaners. Need guidance and suggestions..
Thank you.
I can access to few-layer graphene (non-oxidized) of 3-8 layers thickness and 2-8 micrometers of diameter. Is it possible to break this material into particles of 50-100 nm averaged diameter using standard laboratory equipment without altering its oxidation state?
Thank you in advance
We think that the constants h and reduced h could have equations. Once discovered, the ratio (E/f)=h could be determined theoretically. And the effect on physics is a big change will be that set of constants can be calculated without going through laboratories!
I just doing synthesis for Quartenary Ammonium Chloride in my Lab. When I analysis using FTIR ATR, there's one peak with 150% transmittance. How to fix it? If there's any possibilities for a peak above 100%?
This question is derived from the journal "Tenets of Specimen Management in Diagnostic Laboratory", authored by Rajeshwar Reddy Kasarla and Laxmi Pathak. The journal discussed the significance of having a close and positive working relationship between the physician and the microbiologist, which affects the critical role of the microbiology laboratory in infectious disease diagnosis
How can AI be integrated to physics laboratory learning?
Please share this quick survey of the fundamental concepts and practices that drive the effectiveness of medical lab quality/risk management with as many laboratory professionals as possible https://www.surveymonkey.com/r/QC_Baseline1.
The purpose of the survey is to determine if there is a widespread inconsistency in QC theory and practice. Such a gap would expose patients to significant avoidable risk of missed, delayed, or incorrect patient diagnosis due to lab errors and add costs of unwarranted repeat or additional tests from 'false positives' to patients, insurance companies, and healthcare systems.
Participant scores in this quiz will be revealed immediately upon completion and you are welcome to participate in the review of results and creation of one or more ADLM posters. Abstracts are due Feb 15th!
Here’s one example of an interesting question where participants are not agreeing:
Assume the QC results in an analytical process have a stable error rate with 5% of results reported erroneously high.
If the analytical process 'fails', how high would the error rate need to be to detect, with REASONABLE certainty, a QC result that is outside of 2SDs (ie, violates the 1-2s rule) by analyzing only one QC sample in a single QC run? Is the answer just slightly over 5% ... or would 100% of patent samples need to fail before the lab would know?
LabVine and AWEsome Numbers Inc. have partnered to create Lablogic Innovators to explore new concepts in risk management and solve the problem of this QC Gap. A limited number of spots are available to participate in this interactive group https://awesome-numbers.com/news-and-events/
Questions? Comments? Want to join me to review and publish results?
How could AI transform traditional physics laboratory into an interactive learning hub?
Are there regulatory requirements for the design and organization of rooms for clinical NGS laboratory?
The pre-analytical phase holds significant importance within laboratory workflows, with one of its key steps involving sample collection. Ensuring the integrity of the sample is paramount for various reasons: it directly impacts the accuracy and dependability of test results, influences cost-effectiveness, enhances patient safety, and contributes to standardization and reproducibility. An in-depth knowledge of what constitutes a high-quality sample is indispensable for optimizing laboratory efficiency and ensuring diagnostic test reliability.
This query is based on an article by Rajeshwar Reddy Kasarla and Laxmi Pathak titled "Tenets of Specimen Management in Diagnostic Microbiology." This article is about the importance of a positive working relationship between microbiologists and clinicians in order to give patients the best possible care. Therefore, the purpose of this inquiry is to determine how healthcare professionals' handling of specimens in the laboratory will impact patient outcomes and patient care.
How to apply robotics in physics laboratory experiments?
There are some pieces of equipment that they have in stock and rather enticing prices. I can't find any information regarding customer satisfaction, are they legit, etc. Has anyone dealt with them recently? Did you get what you asked for?
Refurbishing a lab and am looking for similar mobile cabinets (Image attached) so they all match. A colleague indicated our came from Fisher but haven’t had luck finding a match.
Interdisciplinary project-based learning AI laboratories are generally suitable for which age group in Europe and the United States, and are they more effective in cultivating future scientifically literate talents?
I want to remove my Lab from a publication in Researchgate. How do I do that?
In some of the publications introduced, the laboratory where the work
was carried out does not appear, but rather another.
I would like to know if it can be modified. Thank you
Dear parasitologyst researchers, In order to research the helminth eggs in treated water. We looking the most species found and the method used in the laboratory to identify them.
Thanks
From your experience, what is the best model of quiescent leukemia stem cells that can be maintained in the laboratory and routinely passaged for experiments?
Where can I find pigmented short hair guinea pigs for laboratory? Do you know any sellers?
Hello everyone, how do you keep inventory for the chemicals you use in the laboratory? There are some paid software and websites for this, such as 'quartzy'. But is there a website or software that is free and can be used online by more than one user to control stock? Thanks for your recommendations.
Anyone looking for lab bench space in Montreal - Park-Extension Area?
Great access to metro and collaborative research tools.
Is there a benefit to the Caco2 cell intestinal model from antibiotics? I was trained cell culture in the late 90's at HyClone Laboratories. We never used antibiotics. But is seems everyone does now.
Need to calculate the pressure or force generated ibside a 50ml tube filled with water on a Virtex mixer at 2500 rpm
How I can do maintained cultures of Chironomus in the laboratory?
are there any laboratory procedures to extract CARBON from COAL.?
Dear all,
I write a question, which is more commercial than technical.
I am looking for some supplier of chemical laboratory consumer materials, like glassware, vacuum hoses, pipettes/micropipettes, etc, located in the Far East, maybe China and available to trade with European companies.
I am looking for an all-round supplier for place few orders a year but with many items, so as to supply my laboratory from.
Can somebody provide me any indication where I can find a list of them?
Thank you in advance for every reply,
Giacomo
One of the factors that can affect the quality control of the laboratory is the laboratory workers. However, some laboratory workers do not follow the procedures for various reasons. What methods can be done to ensure that these procedures are done properly?
As the world is advancing, new and advance technologies are being invented. Artificial intelligence (AI) is the ability of computers to carry out operations that ordinarily requires human intelligence, such as problem-solving, visual perception, decision making, and communication. In the clinical laboratory, Artificial Intelligence may increase the value of laboratory services and promote patience’s satisfaction and improve the results by using AI’s wide range of possible application. However, factors in technical, ethical, regulatory, and human concerns are some of the difficult and constraints that Artificial Intelligence must overcome before being implemented in the clinical laboratories. Therefore, this discussion aims to give knowledge about the risks in involving and applying the use of artificial intelligence in the clinical laboratory especially when obtaining the results.
Hi,
Can someone please share the Rabies direct immunofluorescence test protocol used in your laboratory. I want to validate the technique that is used my laboratory. Thank you.
Greetings to my fellow members of the academic research community,
My academic journey as a PhD student has presented me with a significant challenge. I've long aspired to join a research laboratory where scientific activities are conducted with genuine enthusiasm and dedication. My passion lies in the pursuit of knowledge and engaging in intellectual discourse with fellow researchers who share my enthusiasm for scientific exploration. Regrettably, my attempts to establish connections with various research laboratories, universities, and distinguished professors have not yielded the anticipated results.
Despite my unwavering commitment to highlighting the availability of financial support from my institution, the responses have been somewhat limited. I've observed that colleagues from different academic institutions readily establish connections with research laboratories and professors, although it appears that their intentions often lean towards short-term engagements rather than meaningful contributions to laboratory work and the broader scope of scientific research.
These colleagues seem to effortlessly secure acceptance letters from these research laboratories, prompting the question: What factors contribute to this noticeable difference in response? I humbly seek your guidance in shedding light on the underlying reasons for this discrepancy. Additionally, I would greatly appreciate any insights, advice, or strategies you may offer to increase the likelihood of receiving acceptance letters that genuinely reflect an interest in my research pursuits and pave the way for long-term collaborative relationships.
I thank you for your invaluable assistance and wisdom.
I wish you a great day,
I plan to add DSpace DS1104 to my Lab, but I am still hesitant and need to hear about your experience with suppliers, including software licence, and any other issues.
Thank you in advance for your valuable comments.
Hi,
We are currently using densitometers from biomerieux to prepare bacterial suspensions. We are wondering if there are any tubes with sterile NaCl solution available on the market other than biomerieux ampules that fit this type of densitometer?
What kind of tubes are you using?
We often use hundreds of them and we feel it is just a waste of money, we were looking for other glass ampules or tubes that are flat-bottomed and not too high so for example you can withdraw some of the suspension with an automatic pipette as well but we can't find anything...
I would appreciate any kind of advice on this!
Good day to whom it may concern!
I wanted to build a simple PEM electrolyzer, could you suggest a good synthesis for the proton exchange membrane?
I work in a electrochemical laboratory, so normally I should be able to find the components for the synthesis if they are not really rare.
Thanks
Hello, I hope you are well, I have been searching and I cannot find the components to make an RNase decontamination reagent in the laboratory, without having to buy the RNase away.
Thanks
I want to invite you to my laboratory to do research in the World Bank and Social Policy field.
I want to do LSV ,CV test of ORR(Oxygen reduction reaction).
But our laboratory don't have the RDE and RRDE electode.
And I was wondering if I can do the tests by magnetic stiring or mechanical stirring?
If there do have some experiments or papers using this way to do ORR test, could you please provide me some files or papers for me to learn?
I'm new to this issue.
Thanks a lot!
My email :[email protected]
As a project of the Materials Science and Engineering (Undergraduate) degree I'm following, my team have been tasked with doping a Si wafer to prepare a p-n junction. I have a few questions regarding this.
- What is a good approach to do a doping with low investment in a laboratory environment?
- Is it possible to dope Si using NH3 to get an extrinsic semiconductor?
- What approach can be used to dope Aluminum into Si wafer?
I have tried searching for information but the closest I could find was this.
I would also appreciate if anyone could point me to somewhere I can find information regarding fabrication of a p-n junction using doping.
Thank you.
In the process of voltage clamp recording, cesium internal solution was commonly used in our laboratory. In general, we used high-chloride cesium internal solution to record mEPSC and mIPSC, but we used low-chloride cesium internal solution for PPR and evoked EPSC. Neither NMDA nor AMPA receptors are chloride channels, so why calculate the equilibrium potential of chloride?
Hi,
I am trying to set a "Lab" for my group and I can't find how to create it following this post:
Is it available in all countries?
BTW. I am working in Tunisia
Thanks for your help.
Noureddine
Does anyone of you have information about the importance of doing experimental activities (on chemistry) in education? Particularly, doing experimental activities in high school.
I simulated a calibration laboratory using MCNP code. The source in the irradiator is Co-60, emitting two gamma rays (1.17 and 1.33 MeV) through decay. The output provided me with the values of dose equivalent ambient at the calibration points. Now, I need to determine the dose equivalent ambient rate with the corrected activity of my source. I followed a similar methodology used for Cs-137, which I successfully validated with experimental data from that laboratory. However, for Co-60, it is not yielding the expected results. I have not yet identified the issue with my analysis.
To obtain H*(10), the chosen tally was F5, and the conversion factors from ICRP 74 were applied using DE/DF on the data card. The input yields H(10) per NPS.
Attached are photos of my methodology to aid in understanding my question.
The methodology of the work, whose photo is attached, was also tested; however, it did not yield results that could be validated by experimental data.
(This work is referenced with the attached photo of its cover)
+1
I work in a single-molecule analysis lab. I have been waiting on a supplier to send sodium bicarbonate for a while, and I want to begin experiments now. We have a stock of sodium bicarbonate from 2017 (five years old). Why can't I use this? Does it really have an expiration date?
I imagine if it does, it may have to do with coming into contact with the air after it was opened so many years ago.
Any help is appreciated. I dont want to do all the experiments only to have them invalidated by the fact that I used old sodium bicarbonate.
Exact chemical structure means exact molar mass and not average molar mass of some kind mixture of homologs. So the Tween and Span series are not good.
Can I ask you a question
Please suggest the laboratory synthesis of ambroxol with the highest efficiency and time
Step 1. Which agent is the fastest to reduce o-nitrobenzaldehyde?
Step 2. Then how to bromine to give 2 amino 3 5 dibromo benzaldehyde?
Step 3. Then how to add trans-4-Aminocyclohexanol?
I need a research work on the topic "availability and effective utilization of chemistry laboratory facilities by students in the senior high schools in the Tamale metropolitan area"
I work in testing laboratory, whereby we are trying to obtain accreditation for Dissolved oxygen using the iodometric APHA method 4500-O-B. In this context, we need to determine the limit of detection as well as limit of quantification for DO.
Any suggestions on how to proceed?
Are there hazards when dealing with Molybdenum trioxide (MoO3) a substance in the laboratory?
What safety equipment should be worn? What are the conditions in the laboratory that must be provided?
Thanks
I am working to check the accuracy between Ultrasound Machine and Pathology Lab results for Kidney disease.
Which statistical test to use for comparison of these two independent variables ?
Topic is: Accuracy of Ultrasound Echogenicity with Serum Creatinine in Renal Parenchymal Disease.
There is a 13 level multilevel inverter (DC-AC). I am working on it in my Lab. However, there are some annoying spikes on my waveform. I wana eliminate them.
Storage and maintenance of pathogens is a costly and time-consuming affair, the recent study indicated that most of the pathogenic bacteria can be stored for several months at room temperature in sterile tap water without any hustle.
Ref DOI: 10.13140/RG.2.2.34672.84480
Technical Report Survival of pathogenic bacteria in different types of water
The EU regulations are more strictly than the regulatioins in China. For instance some isolation coatings from China can contain Pb. We would like to proof if a coating contains Pb or not before we ask a laboratory to check the exact amount.
Hello
I am Anouk, 22 years old and graduated from professional bachelor biomedical laboratory technology me majoring in pharmaceutical and biological laboratory technology.
I would like to switch to a master degree next year but I am hesitating between 2 directions namely,
- Master in Biology
- Master in Biomedical Laboratory Technology
My interests include everything related to science, lab and nature. I love the combination of these. This year I did an internship around the ecotoxicological evaluation of sludge. This was something I considered extremely interesting.
Please get in touch as I would like to receive good advice from experience experts.
Thank you in advance
Kind regards
Anouk
This position is not funded by our laboratory, but we plan with the applicant to apply to "Fondation de France", to the proposition "Recherche fondamentale et translationnelle sur le cancer (tumeurs solides et liquides).
The project that we proposed is very likely to be funded since it has been already very well evaluated by the fondation.
Our laboratory has a PerkinElmer (model: AAnalyst 800) atomic absorption spectroscopy. Recently, the performance of the device has encountered a problem. When the circuit breaker of the device automatically turns off the air compressor, the flame also turns off, and a "No air pressure" error appears on the screen. Due to this issue, we are unable to use the device.
It should be noted that the air compressor has been checked and there is no problem associated with it.
If you can help with your guidance, it will undoubtedly be a great favor to many of our students who are having trouble doing their dissertation tests.
I am working on microfibers issue and I want to get ready made laboratory grade microplastics/microfibers. I am not convinced what the students are doing to prepare by using cutters in the lab. Because, first of all cutting by hand to micro level is very daubtful and secondly there will be surface modification during the cutting process. Therefore, I wan to really get the micofibers/plastics. Any help is very much appretiated.
Our Lab's FTIR knob broke. Can it give right results without the knob touching the polymer just by the diamond sensor in FTIR?
I want to use an offline application of a virtual Chemistry Laboratory software that can help students in institutions that lack some basic laboratory equipments to be able to understand chemistry practical.
Applications or softwares that can help them practice simple chemical reactions.
I do have a couple of virtual applications but I need a few suggestions. Thank you
In the laboratory we would like to reuse Elisa plates, but so far we have not found a washing technique that allows us to do so. Have you reused the plates? If so, what washing method is done? or is it not possible to reuse it?
I appreciate your answers
How can one preserve saffron that is harvested in the field. Because we can only measure it after a few days in the laboratory
Hi
I need that for my dissertation, but I can't find a file about it. Can anyone guide me, please??
To conduct in vivo studies to evaluate the effectiveness of cell therapy
