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Philosophy in the conventional meaning of the term came to an end with Hegel’s dialectics. Because, if the aim of all previous philosophy was to find the final, absolute, ultimate truth of the world; the ‘Mind of God’ etc.; Hegel’s dialectics has convincingly showed that such an aim can never be achieved. "The Infinite - As a Hegelian Philosophical Category and Its Implication for Modern Theoretical Natural Science":
Philosophy in the form of dialectics has to become an integral part of the positive empirical sciences (related to human social/historical practice, technology etc.) that originated with primitive man. But what was previously unconscious and rather instinctive, dialectics after Hegel becomes a consciously scientific method of acquiring positive Knowledge of the history of Man and the World, actively changing the world to progressively narrow the contradiction between the two, but without any end, ever. As Engels said, “What still independently survives of all former philosophy is the science of thought and its laws - formal logic and dialectics. Everything else is merged in the positive science of nature and history.' Anti-Dühring,
But what’s of post-Hegelian philosophy? If natural science, in spite of its phenomenal achievements still finds itself begging at the door of theology, it has the satisfaction of seeing philosophy sink lower still. Modern philosophy maintains (as Engels put it) a pseudo existence in the state appointed academia, where, position-hunting, cobweb-spinning eclectic flea-crackers occupy the chairs of philosophy. Instead of looking for profound truths in the wide world of nature and human society like their predecessors, these namesakes either work openly as the apologists of monopoly capitalism or look inwards to “self” (existentialism) or to language(linguistic philosophy) etc. ad nauseam to hunt for absolute truth.
Stephen Hawking is absolutely right when he says: “In the eighteenth century, philosophers considered the whole of human knowledge, including science, to be their field and discussed questions such as: Did the universe have a beginning? However, in the nineteenth and twentieth centuries, science became too technical and mathematical for philosophers, or anyone else except a few specialists. Philosophers reduced the scope of their inquiries so much that Wittgenstein, the most famous philosopher of this century, said, ‘The sole remaining task for philosophy is the analysis of language.’ What a comedown from the great tradition of philosophy from Aristotle to Kant!”. S Hawking, “A Brief History of Time”, Bantam Books, p. 174-175 (1990)
But it is modern natural science that is hiding its bankruptcy and confusion under the mystery of mathematics and like an ostrich is burying its head in the sand of causality and determinism. The philosophy of Heraclitus, Epicurus, Hegel, Marx and Engels means nothing to it. Modern natural science, has come under total subjugation of monopoly capital, and has dishonoured the great tradition set by Copernicus, Galileo and Darwin. A natural science, which was once inspired by the revolutionary bourgeoisie and created these giants of science, has now become a lap dog of reactionary/regressive monopoly capital. Modern natural science wants to bring back the absolutist and obscurantist science of feudalism to serve the interest of moribund monopoly capital. It is churning up a “complete theory” of exquisite mathematical beauty and of absolute validity for all eternity; a theory, which has no empirical foundation. Like modern philosophy, present day natural science has reduced its scope to mere application of the absolute truth it has attained in the realm of nature. Only those facts that conform to this truth are of interest to science, those that do not, remains in the realms of the Creator or at best are Kantian “thing in itself”. Thus, we have not only a “comedown from the great tradition of philosophy” but a comedown from the great tradition of natural science too.
G.W.F. Hegel said, “All that is real is rational; and all that is rational is real.”; but with the important qualification, “The reality proves itself to be the necessary in the course of its development.”
As Frederick Engels extrapolated on Hegel’s dialectical statement, “… so, in the course of development, all that was previously real becomes unreal, loses it necessity, its right of existence, its rationality. And in the place of moribund reality comes a new reality capable of living — peacefully if the old has enough intelligence to go to its death without a struggle; forcibly if it resists this necessity. Thus, the Hegelian proposition turns into its opposite through Hegelian dialectics itself: All that is real in the sphere of human history, becomes irrational in the process of time, is therefore irrational by its very destination, is tainted beforehand with irrationality, and everything which is rational in the minds of men is destined to become real, however much it may contradict apparent reality of existing conditions. In accordance with all the rules of the Hegelian method of thought, the proposition of the rationality of everything which is real resolves itself into the other proposition: ‘All that exists deserves to perish’ *”. "Ludwig Feuerbach"
It is obvious that the monopoly capitalism of the present time, with its parasitic economic, political, military etc., domination of humanity and its decadent ruling idea based on concocted mathematical theories of physics (and cosmology), has become vulnerable to conscious and active resistance and CHANGE!
"New Physics -The Negation of Einstein's Theories of Relativity The Real Phenomenology of Space-Time-Matter-Motion":
*The words of Mephistopheles in Goethe’s Faust:. “Alles was entsteht, Ist wert, daß es zugrunde geht!”
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Copy: Abdul Malek added an answer 46 minutes ago
Jürg Wyttenbach >“You totally mix up the current reality!”
This is your idle opinion, my friend! Any intellectual activity on a certain issue, which does not consider changing it, has no meaning. “The philosophers have interpreted the world, in various ways; the point however is to change it”. Karl Marx
Please read my comment carefully, especially the part: “It is obvious that the monopoly capitalism of the present time, with its parasitic economic, political, military etc., domination of humanity and its decadent ruling idea based on concocted mathematical theories of physics (and cosmology), has become vulnerable to conscious and active resistance and CHANGE!
Just think of the great potential of (vast majority of modern humanity supported) ACTIVE RESISTANCE to monopoly capitalist aggression in the Middle East, militarily. And scientifically, the new Quantum-Dialectical Physics! "New Physics -The Negation of Einstein's Theories of Relativity The Real Phenomenology of Space-Time-Matter-Motion":
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In the mechanism of resistance to insecticides, why is metabolic resistance stronger and more frequent than target site mutations?
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Metabolic resistance, often referred to as detoxification, involves the organism's ability to metabolize or break down a substance, such as a pesticide or drug, into less toxic forms. Target site mutation, on the other hand, involves changes in the specific site where the substance typically binds, such as a receptor or enzyme, rendering it less effective or ineffective. metabolic resistance can be stronger than target site mutation due to its versatility, multiple potential targets, redundancy, energy cost considerations, and evolutionary history.
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I am doing impedance measurements on my materials and I want to analyze in particular the real component of complex conductivity as a function of frequency.
I am not sure, but is it valid to take the real impedance, Z'(ν), as the resistance at a given frequency and calculate σ'(ν) = d/(Z'(ν)*A), where d and A are the thickness and area of my sample?
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From complex impedance, first obtain complex admittance. The real part of admittance is conductance. From the sample thickness, and effective electrode area, you can calculate conductivity using conductance. However, remember, this is AC conductivity, different from the DC counterpart, that is independent of frequency.
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Hi. I am familiar with the following process for calculating conductivity from a Nyquist plot:
1. Run impedance on potentiostat
2. Plot - Imaginary Z vs Z
3. Generate equivalent circuit
4. Fit data
5. Calculate conductivity by entering the resistance value, thickness, and diameter of sample
My confusion is that, in the past, my spectra always had a semicircle. Now I am running samples which are giving basically a 45 degree line that starts to the right of 0 on the X axis. I believe I have an equivalent circuit (Resistor + Constant Phase Element/Resistor + Warburg element). My question is, are you able to calculate conductivity as long as you can extrapolate the resistance? In other words, if you have an equivalent circuit which contains a resistor, can you always calculate the conductivity? Or do you need a semi-circle? Thanks.
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Yes, you can just get the series resistance or bulk resistance by looking at the nyquist plot and checking the first x axis intercept. Im not sure exactly what not having a semicircle means.
Heres a paper that obtains Rs via nyquist plot with no semicircle. ( check supoorting info to see the plots) https://doi.org/10.1002/smll.201704497
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I have a question about estimating the antenna efficiency measurement error when using an improvised Wheeler cap with bad surface resistance?
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From the paper below it would seem that the cap only acts as a reflector of radiated power (not a resonator) so if you can estimate the reflection coefficient it may allow you to compensate for it. I'd expect that the reflections should be in the high 90% though which won't affect the result much.
You may have better articles available than the one below, but that looks like it might have enough to work with!
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What is the breakpoint diameter for florfenicol and oxytetracycline in the disk diffusion method, indicating susceptibility or resistance to these antibiotics in the tested salmonella strain?
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The breakpoint diameter for florfenicol and oxytetracycline in disk diffusion testing can vary depending on factors such as the specific organism being tested, the susceptibility testing method used, and guidelines from organizations such as the Clinical and Laboratory Standards Institute (CLSI) or the European Committee on Antimicrobial Susceptibility Testing (EUCAST).
To obtain accurate and up-to-date information on breakpoint diameters for florfenicol and oxytetracycline, it's best to consult the most recent CLSI or EUCAST guidelines or refer to the recommendations provided by your local regulatory authority or clinical microbiology laboratory.
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Hi, I have transfected my HEK293 cells with pcDNA3.1_plasmid of interest with EGFP by using lipotransfection method. Post transfection 48h the egfp expression looks good with more than 50% transfection rate. Started G418 selection (DMEM+10% FBS+ 2mg/mL G418). Post transfection 48h, the cells transfer from 24wp to 12wp to create space for G418 medium to get to non-transfected cells. Medium replacement done daily, and after a week, fresh selective medium is prepared. Massive cell death observed after 2 days of G418 selection.
Day 7, 95% of non transfected cell die. Colonies/ egfp rounded cell clump together can be observed and a lot of resistant cells survived but did not attached under the G418 selective stress.
Day 8, the selective medium reduce to 1mg/mL and Day 10 reduce to 500ug/mL and day 12 reduce to 250ug/mL hoping that the resistant cells will attach and starting to expand.
Unfortunately, the non transfected cells starting to grow rapidly and the cells with EGFP did not grow so much. Any comments and thoughts are welcome. The reason I use 2mg/mL from to start becuase I have done 1mg/mL to kill the HEK293 but it wasn’t effective. The active G418 percentage is 80.9% and I have reconstituted G418 with 100mM HEPES buffer And filtered.
I have read about for the survival cells to expand it might take a long time under the selective pressure. When is the right time to reduce the antibiotic?
the attached image is Day 10 under G418 selection. Should I be more patient and keep the G418 concentration high and wait for the colonies to attach and expand?
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Sabine Strehl thank you for answering! Under G418 selection pressure, the resistant cells did not die but not exert their typical morphology even after 10 days. The non resistant cells die 99% but not completely, as I reduce the antibiotic level the non resistant cells overgrowth than the resistant cells that express EGFP and slowly my resistant cells reduce and die off and non resistant cells overgrowth. I use medium with G418 for 7 days then prepare a fresh one, but on 7th day of the medium, the antibiotic seems wear off the potency after a few water bath thaw.
I will repeat the transfection and selection process. Thank you for your suggestion.
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Can anyone suggest some monoembryonic rootstock of mango with abiotic or biotic resistance?
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the cultivars ‘Van Dyke’, ‘Irwin’, ‘Kent’, and ‘Tommy Atkins’ demonstrate greater resistance to dry conditions when grafted onto seeds of the ‘Arauca’ rootstock in Colombia
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Hello. This image is taken from la7 cancer stem cells. It seems that the cells that have a purple halo and seen shiner than other cells have a high resistance to starvation conditions. What kind of cells do you think these are and what is the reason for their resistance?
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The cells you've described with a purple halo and shinier appearance in the LA7 CSCs culture, which demonstrate a high resistance to starvation, could be presumed to be a subpopulation within the cancer stem cells known for their resilience in adverse conditions. The existence of such cells that appear distinct in terms of color and brightness could indicate a subset of cells with certain biological properties that confer this resistance.
Without a detailed analysis through biochemical and genetic investigations, it's hard to determine the exact identity of these cells.
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due to different patients being resistant to usual medications being prescribed to others, how can antibiogram be of help in determining the perfect antibiotic to be prescribed to the patient because antibiotics varies in treatment and dosage.
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Antibiograms play a crucial role in helping medical professionals optimize antibiotic prescribing by providing valuable information on antibiotic susceptibility patterns. By using this information to guide empirical therapy, tailor treatment, prevent overuse and misuse of antibiotics, support antimicrobial stewardship efforts, and monitor resistance trends, healthcare providers can effectively combat antibiotic resistance while ensuring optimal patient care.
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Is it possible to conduct PCR to check for resistant genes in bacteria and have no bands? All have bacteria have no bands of the resistant genes
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You need a positive control, a bacteria in which the PCR amplification is positive and see a band when you run the electrophoresis gel. Also, the resistance genes in some cases are diverse in sequence or the bacteria lack of that genes. First, you should check that your primers give you an amplification product with a positive control.
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An important factor to consider when providing antibiotics is the possibility of the bacteria gaining resistance to it. My questions pertains to how these bacteria are able to gain resistance and the mechanisms involved for it to happen? And what can we possibly do to lessen the chances of this happening?
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Antibiotics are known to alter bacterial processes and reduce their chances of developing. However, certain bacteria have evolved throughout time, allowing them to survive the effects of antibiotics, a phenomenon known as antibiotic resistance. In this scenario, two strategies for bacteria to resist the effects of an antibiotic are:
  • Stopping the antibiotic from reaching its target at a high enough concentration: Bacteria can reduce the permeability of the bacterial cell's membrane, making it difficult for the antibiotic to pass. They additionally have the ability to alter the antibiotic by producing enzymes that disrupt the chemical groups of the antibiotic, preventing interaction between the target bacterial cell and the antibiotic.
  • Modify or circumvent the antibiotic's target: Bacteria can conceal their target by modifying their general composition or structure. This protects the target, preventing the antibiotic from interacting with it.
With antibiotic resistance becoming a serious concern, it is important to determine ways to reduce it. Examples of ways to prevent it are as follows:
  • Only use antibiotics as prescribed. Complete the entire course of medication; do not skip any doses
  • Never ingest antibiotics intended for other people
  • Don’t take antibiotics, if not necessary
Resistance mechanisms – Antibiotic resistance – ReAct. (2021, December 9). ReAct. https://www.reactgroup.org/toolbox/understand/antibiotic-resistance/resistance-mechanisms-in-bacteria/
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Povidone iodine is cheap and active against all type of micro organism including bacteria,virus, fungus and protozoa; with no risk of developing resistance. I have been using 2.5% topical povidone ( 10% diluted to 2.5%) iodine for common type of conjunctivitis successfully for the 10 years. Now a days 5% ophthalmic preparation is available which is more costly than topical preparation. But the most of the ophthalmologist are not interested to use this cheap drug in external ocular infection.
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Prescribing different costly ophthalmic antibiotics for conjunctivitis instead of a povidone iodine preparation depends on various factors, including the nature of the infection, patient factors, and healthcare provider preferences. Here are some potential advantages of using ophthalmic antibiotics over povidone iodine for treating .conjunctivitis,Targeted Antibiotic Therapy,Rapid Symptom Relief, Prevention of Complications, Reduced Risk of Allergic Reactions, Preservation of Normal Flora, Convenience and Ease of Use, Guidelines and Clinical Practice, While ophthalmic antibiotics may be more costly than povidone iodine preparations, their targeted antimicrobial activity, rapid symptom relief, and potential to prevent complications justify their use in certain cases of bacterial conjunctivitis.
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Can heterogeneous resistance, indicated by the presence of small discrete colonies inside the zone of inhibition, affect the zone diameter in disk diffusion susceptibility testing?
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Yes, heterogeneous resistance can indeed affect the zone diameter in disk diffusion susceptibility testing.
In disk diffusion susceptibility testing, antimicrobial susceptibility of bacteria is assessed by measuring the zone of inhibition around an antimicrobial disk on a culture plate. The diameter of this zone is indicative of the susceptibility of the bacteria to the antimicrobial agent.Heterogeneous resistance refers to the presence of subpopulations of bacteria within a culture that exhibit varying degrees of susceptibility to the antimicrobial agent being tested. This means that while the majority of the bacteria may be susceptible to the antimicrobial, there could be small subpopulations that are resistant.When performing disk diffusion testing, if there are subpopulations of resistant bacteria within the culture, the zone of inhibition may appear larger than expected. This is because the susceptible bacteria surrounding the resistant subpopulations are still inhibited by the antimicrobial, leading to a wider zone of inhibition. As a result, the zone diameter may not accurately reflect the true susceptibility of the bacterial population as a whole.
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I am finding difficulty in judging input settings for finding electrical resistance or conductivity of hardened epoxy composite.
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Hello,
There is a booklet from Textronic (ex Keithley):
Low Level Measurements Handbook -7th Edition Precision DC Current, Voltage, and Resistance Measurements:
The manual also mentions resistivity measurements:​https://download.tek.com/manual/2450-901-01E_Sept_2019_Ref.pdf
Hope this helps.
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If it's undoped Si wafer, it should not be n or p type. But MTI corporation is sellinng Undoped Si wafer as n-type with resistivity >1000 ohm.cm.
I have also measured the hall of the undoped n-type Si wafer and it's found to be n-type with carrier density of 6.25*10^12 cm^-3.
How Is this possible? I am looking for the explanation.
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Hi! I have the same question as yours. Did you find any explanation for this?
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I am working on the design of an image encryption algorithm. The algorithm has a sound score of entropy, low correlation, resistance to anti-cropping attacks, and resistance to salt and pepper noise. The only issue with the algorithm is its resistance to counter gaussian noise.
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IYH Dear Rashad Ali
Generally, no. Double Random Phase Encoding is generally considered an irreversible image encryption technique due to its underlying mathematical nature. Why? The main reason behind this lies in the convolution process applied during encoding, which blends the original img with a pseudorandom reference function generated via two separate random phases. Upon decryption, the inverse operation requires precise knowledge of both random phases employed initially—otherwise, perfect recovery of the original image becomes impossible.
Certain variations of the DRPE algo are explored for potentially reversible scenarios. Extensions incorporate auxiliary channels or side info alongside the encrypted imgs themselves, enabling partial restoration even when facing missing or corrupted phase terms.
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I am trying to set up a Graphab project and to calculate a linkset. This works fine when using a small crop of the original research area with an external raster file containing resistance values, or when assigning some class-specific resistance values. However, when I use the full extent of the map in combination with an external raster file that contains the resistance values, I get the following error:
"java.lang.RuntimeException: java.lang.IllegalStateException: Negative or null cost is forbidden. Check your cost."
There are no null or negative values in the resistance raster, so what shall I make of this message? Could it have been caused by some other issue not accurately reflected in the error message?
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Update: my previous answer works because it pushes all values >=1, this can be achieved without converting it to factor by simply adding a 1 to your values. Ultimately the cost surface cannot have values <1, and this is the case also for other connectivity software such as Omniscape.
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I am having difficulty finding formulas for calculating the resistance and inductance of a PMSM motor
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Dear Lai Tinh,
it seems, you'd like to do a "sensorless" vector control for PMSM. Maybe this is a helpful article to get introduced to the topic and its nomenclature: .
Note that the rotor usually is a magnet (without windings), thus the electrical resistance of it should be of minor interest (except you want to know electrical losses due to induced eddy current). However, the absolute inductance describes the relation between magnetic flux linkage and the electric current -- but inductance itself depends on the current, which will make the calculation more extrusive, especially if the motor material has nonlinear magnetic permeability.
I hope the hints are helpful.
Best Regards
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Does conductivity increase with temperature in metals and relationship between resistance and temperature difference between semiconductors and metals?
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Dr Himmat Singh thank you for your contribution to the discussion
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How the adhesion of thick SU8 to copper seed layer can be improved ?
And which SU8 resist would you recommend for MEMS ?
Thank you.
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Use OmniCoat. It is an adhesion promoter that worked with copper among other materials and can also work as a release layer for SU8. You can use pretty much any formulation for the SU8 for MEMS. It'll all depends on you process, layer thicknesses, and aspect desired aspect ratios. 2000-series is a good start. Check out Kayaku Advanced Materials for data sheets and more information.
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What happens to electrical resistance at low temperatures in the phenomenon of superconductivity and why do superconductors have no resistance?
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Dr Stanislav Dolgopolov thank you for your contribution to the discussion
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Question about how and types of methods to optimize steel structures for seismic resistance
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I want to learn optimization
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MATLAB,
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I am not sure if Simulink has such resistor models already built in it but below is a simple Matlab script that can be used to model such a resistor whose resistance value varies with time. I have used the sine function to model the transient variation. You can define anything as per your needs.
% Define time vector
t = linspace(0, 10, 1000); % Adjust time range and resolution as needed
% Define a function for temperature variation with time (customize as needed)
temperature = 25 + 10 * sin(2 * pi * 0.05 * t);
% Define a function for resistance variation with time and temperature (customize as needed)
resistance = 10 + 5 * sin(2 * pi * 0.1 * t) + 0.1 * (temperature - 25);
figure;
plot(t, temperature, 'LineWidth', 2);
xlabel('Time (s)');
ylabel('Temperature (°C)');
title('Resistor Temperature vs Time');
figure;
plot(t, resistance, 'LineWidth', 2);
xlabel('Time (s)');
ylabel('Resistance (\Omega)');
title('Variable Resistor: Resistance vs Time');
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Is heat directly or inversely proportional to resistance and why resistance decreases with increase in temperature for carbon?
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Md. Tanvir Hossain thank you for your contribution to the discussion
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What is the best specific resistance of a conductor increases and relationship between temperature and specific resistance of conductor?
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Dr Jan- Martin Wagner thank you for your contribution to the discussion
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Is resistance directly proportional to temperature in semiconductor and how increase in temperature affects the conductance of weak electrolytes?
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Dr Vijay Kumar Bodarya thank you for your contribution to the discussion
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Why resistivity of conductor increases with temperature and that of semiconductor decreases with temperature?
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Dr Vijay Kumar Bodarya thank you for your contribution to the discussion
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What is the best conductor of electricity and why does increasing temperature increase the specific resistivity on conductors whereas decrease the specific resistance of semiconductors?
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Dr Naresh,
I'll ask you directly: are you sincere in your interest in the origins of superconductivity or are you simply posting basic questions, hoping for people to answer, and so boost your RG 'score'?
You have posted literally hundreds of basic questions this year, most of which can be resolved with a Google search.
Why?
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What is the reason for the resistance change in a normal metal with increasing temperature while that of superconductors remains constant?
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Prof. Rk Naresh
Resistivity in BCS superconductors is equal to zero below the second-order transition temperature. See for example
As the temperature is increased in a normal metal, the scattering mechanism that prevails in normal metals is electron-phonon scattering.
See for example:
Electrons and Phonons: The Theory of Transport Phenomena in Solids. Oxford Classic Texts in the Physical Sciences, by Prof. J. M. Ziman
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What causes superconductivity at ultra low temperatures and why does resistance decrease with increasing temperature for some metals but not others?
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Dear Prof. Rk Naresh at ultra-low temperatures, superconductivity is found in the isotope 3He, there are several phases.
Please check the cryogenic section in the following wiki:
Resistivity decreases in most metals, the mechanism is the phonon electron scattering and also the electron-electron scattering at lower temperatures.
For increasing resistivity in metals, see for example the wiki dedicated to Prof. Kondo and his Kondo effect
Best Regards.
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What is the highest critical temperature of superconductor and when temperature of a semiconductor is increased then its resistance decreases?
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See
Note these
  • As of 2023, the material with the highest accepted superconducting temperature was highly pressurized lanthanum decahydride, whose transition temperature is approximately 250 K (−23 °C) at 200 GPa
  • At standard atmospheric pressure, cuprates currently hold the temperature record, manifesting superconductivity at temperatures as high as 138 K (−135 °C).
  • In 2015, an article published in Nature by researchers of the Otto Hahn Institute suggested that under certain conditions such as extreme pressure H2S transitioned to a superconductive form H3S at 150 GPa (around 1.5 million times atmospheric pressure) in a diamond anvil cell.[9] The critical temperature is 203 K (−70 °C) which would be the highest Tc ever recorded and their research suggests that other hydrogen compounds could superconduct at up to 260 K (−13 °C)
  • On 31st of December 2023 "Global Room-Temperature Superconductivity in Graphite" was published in the journal "Advanced Quantum Technologies" claiming to demonstrate superconductivity at room temperature and ambient pressure in Highly oriented pyrolytic graphite with dense arrays of nearly parallel line defects
Hope these helps
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Do superconductors have zero resistance and why the conductivity of metals does decreases with rise of temperature while that of semiconductors increases with temperature?
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Superconductors and Resistance:
Yes, superconductors are known for having zero electrical resistance below a specific temperature called the critical temperature (Tc). This means that an electric current can flow through a superconductor indefinitely without losing any energy due to resistance. This phenomenon is the foundation of many technological applications of superconductors, such as high-speed trains and powerful electromagnets.
Conductivity in Metals:
You're correct that the conductivity of metals generally decreases with increasing temperature. This is because as the temperature rises, the atoms in the metal vibrate more intensely. These vibrations act as obstacles for the movement of free electrons, which are responsible for carrying electric current. As the electrons encounter these obstacles more frequently, the overall conductivity of the material decreases.
Conductivity in Semiconductors:
However, the behavior of semiconductors with respect to temperature is slightly different. In semiconductors, the conductivity actually increases with increasing temperature. This is because both the number of free electrons and the amount of "holes" (vacancies where electrons could be) increase with temperature. While the increased vibration still scatters electrons, the additional charge carriers can overcome this effect to some extent, leading to higher overall conductivity.
Here's a summary:
MaterialResistance with Temperature IncreaseSuperconductor (below Tc)ZeroMetalIncreasesSemiconductorDecreases initially, then increases
drive_spreadsheet
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Why resistance is inversely proportional to relaxation time and relationship between conductivity mobility and carrier concentration of a semiconductor?
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Understanding the Relationship between Resistance, Relaxation Time, and Conductivity:
Resistance (R) is a material's opposition to the flow of electric current. In conductors like metals, this opposition arises due to collisions between free electrons (electrons not bound to specific atoms) and the metal's positive ions (atomic cores). These collisions impede the smooth flow of electrons, causing resistance.
Relaxation time (τ) represents the average time between these collisions. Imagine electrons traveling through a corridor with obstacles. The time it takes for an electron to hit one obstacle and then another defines its relaxation time.
The relationship between resistance and relaxation time is:
R ∝ 1/τ (where ∝ represents "proportional to")
This means as the relaxation time increases (fewer collisions), the resistance decreases (easier flow of electrons) and vice versa.
Conductivity (σ) is the inverse of resistance, signifying a material's ability to conduct electricity. It relates to how easily current flows:
σ = 1/R
Therefore, from the first equation, we can also say:
σ ∝ τ
Relating Conductivity, Mobility, and Carrier Concentration in Semiconductors:
Semiconductors are materials with conductivity between conductors and insulators. Their conductivity depends on the number and mobility of charge carriers, typically electrons or holes (vacancies where electrons would be).
Carrier concentration (n) refers to the number of charge carriers per unit volume in the material. More carriers generally lead to more current flow, potentially increasing conductivity.
Mobility (μ) signifies the ease with which these carriers move under an electric field. Carriers with higher mobility experience fewer collisions and move faster, enhancing conductivity.
The relationship between conductivity, mobility, and carrier concentration in a semiconductor is:
σ = n * e * μ
where:
  • e is the charge of an electron (constant)
Therefore, for semiconductors, increasing either carrier concentration or mobility can lead to higher conductivity.
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Is temperature directly proportional or inversely proportional to resistance and relationship between conductivity and molar conductivity with temperature?
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Relationship between Temperature and Resistance:
The relationship between temperature and resistance is not directly proportional nor inversely proportional. It's more nuanced:
  • In most conductors (metals): As temperature increases, resistance also increases. This is because increased thermal motion disrupts the flow of electrons, making it harder for them to move freely.
  • In semiconductors: The relationship is more complex. Usually, resistance decreases with increasing temperature. This is because higher temperatures excite more electrons into the conduction band, increasing their mobility.
Therefore the statement is not entirely accurate.
Relationship between Conductivity and Molar Conductivity with Temperature:
Conductivity (σ) and molar conductivity (Λ) are inversely proportional to resistance (R). This means that as resistance increases, both conductivity and molar conductivity decrease, and vice versa.
The relationship between conductivity and temperature depends on the material:
  • In conductors: As temperature increases and resistance increases, conductivity decreases.
  • In semiconductors: As temperature increases and resistance generally decreases, conductivity increases.
Therefore, the relationship between conductivity and temperature depends on the type of material.
Similarly, the relationship between molar conductivity and temperature also depends on the material, mirroring the behavior of conductivity.
I hope this clarifies the relationships between temperature, resistance, conductivity, and molar conductivity.
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I tried to coat the surface of Li metal with PVDF and DMF solutions. The coating was successful, but after coating, I put it to dry, and during assembly of the cell, I saw the Li metal was not shining anymore and had a high resistance.
Can anyone suggest to me how I can make it stable or what precautions I should take during coating?
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Sir!
You did not give much detail, so I will not, either.
Some coating under vacuum by HMDSO plasma will be a good protection against the influence of air and humidity, at least for a while. You will find some literature on the process.
Best wishes from Heinrich
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How does the resistivity of a conductor and a semiconductor vary with temperature and relation between temperature and resistance?
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Dr Armin Dadgar thank you for your contribution to the discussion
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Why does speed of the molecule increase with temperature and why does resistivity of semiconductors decrease with increase in temperature?
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Dr Sukru Aktas thank you for your contribution to the discussion
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Elaborate on why transcriptomics and comparative genomics are chosen as the primary methods for investigating fungicide resistance in Alternaria alternata?
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Transcriptomics and comparative genomics are the most standard techniques in NGS, and I would say "easy to interpret" comparing to any other technique such as CHIP-seq, ATAC-seq and many others.
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Miracle F1 (cauliflower, Bejo Zaden ) was used as Xanthomonas campestris races differential variety with proposed gene R3 (Taylor JD, Conway J, Roberts SJ, Astley D, Vicente JG. Sources and origin of resistance to Xanthomonas campestris pv. campestris in Brassica genomes. Phytopathology. 2002 Jan;92(1):105-11.; Vicente JG, Taylor JD, Sharpe AG, Parkin IA, Lydiate DJ, King GJ. Inheritance of race-specific resistance to Xanthomonas campestris pv. campestris in Brassica genomes. Phytopathology. 2002 Oct;92(10):1134-41.)
Now, it is impossible to find the seeds at Bejo Zaden site.
Is production of Miracle F1 discontinued? What variety can be used as R3 source instead of Miracle F1?
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Hi, Joana, does it mean that we are not capable now to compare new potential differential plants against original variant of putative Rxcc3 gene? It does destroy the current Xcc race differentiation system, does't it? I hope there is a solution for this problem.
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Does humidity increase air resistance and what happens to the particles of a substance as its temperature increases?
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Dr Murtadha Shukur thank you for your contribution to the discussion
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Does resistance increase when temperature rises and what does the temperature of a substance relate to the movement of particles in a substance?
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Yes, in most cases, the resistance of a substance increases as its temperature rises. This is true for conductors like metals, but not for all materials. Here's the breakdown:
Conductors:
  • Imagine electrons flowing through a metal like tiny cars on a highway.
  • When the temperature rises, the atoms in the metal vibrate more intensely.
  • These vibrating atoms act like bumps on the highway, making it harder for the electrons to flow smoothly.
  • This increased difficulty translates to higher resistance.
Insulators:
  • In insulators, the electrons are tightly bound to their atoms and don't move freely.
  • However, some temperature effects can change the material's structure or create imperfections, leading to an increase in resistance in some cases.
Semiconductors:
  • These materials behave differently depending on temperature.
  • Usually, their resistance decreases with increasing temperature due to different mechanisms related to their band structure.
Temperature and Particle Movement:
  • Temperature is directly related to the kinetic energy of particles in a substance.
  • Higher temperature means faster-moving particles.
  • In gases and liquids, these faster-moving particles collide more frequently, which can also hinder the flow of current and contribute to increasing resistance in some cases.
Exceptions:
  • Some special materials, called superconductors, lose all resistance at very low temperatures.
  • Certain resistors are designed to have a negative temperature coefficient of resistance, meaning their resistance decreases with temperature.
Overall, remember that the relationship between temperature and resistance is complex and depends on the specific material and its properties.
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I know that most wood degrading fungi have developed a certain resistance and protection mechanism against H2O2 and its radicals, but does someone know the MOST resistant fungus and maybe also the mechanisms by which it gets such a high resistance?!
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The ,most resistant likely would be the black fungi.
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Dear All,
I am working on a university project where I am converting a fuel-operated ferry that runs between Tahiti and Moorea. The initial phase of my project involves determining the energy required for a round-trip journey under the current fuel-based parameters of the ferry.
To calculate this, I have considered factors such as resistance to forward movement caused by the wet surface, wind resistance, etc. The ferry has a capacity of 1,150 tons, and the total distance for the round trip is approximately 50 km. Additionally, I factored in varying speeds experienced in port and at sea (max 20 kts).
Based on these considerations, I have calculated an estimated energy requirement of 16 MWh for the round trip. However, I am unsure if this figure is accurate or realistic.
I would greatly appreciate any insights or feedback on whether this energy estimation seems correct.
Thank you for your assistance
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I mixture carbon with silicon , then coat ( thin layer as a film) it onto copper with it to make anode for lithium ion battery
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This is nothing to do with the question, but I found it interesting to my lower level of understanding of this subject and thought that it might be of interest to other RG readers:
The 'snapshot' is of the initial introduction to the subject.
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Can anyone suggest me How to find the resistivity of cold plasma in DBD at atmospheric pressure?
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Measure the internal resistance of your whole circuit (without plasma) and then switch on your plasma and measure the IV characteristics of it.
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I got this plasmid from Addgene (https://www.addgene.org/83481/) that I want to put into some mouse immortalized myeloid cells.
The basticidin resistance gene is driven by human phosphoglycerate kinase 1 promoter (hPGK). Will this be a problem?
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Does the other way around work too ? Express a gene under mouse PKG promoter in human cells ?
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Hello, I am seeing inconsistent passivation results in my stainless steel finishing process. I am welding 316 stainless steel, then grinding down the weld to achieve a smooth finish, then electro-cleaning the mechanically altered surface with a handheld electropolisher.
The problem is that sometimes I will get grooves in the ground surface during that step (chatter-like marks perpendicular to the grinding direction) that eventually rust in a salt spray test, even after electrochemical cleaning. I've attached a picture of the marks that show up after the grinding step.
Any ideas on how to avoid rust in this scenario? Is the grinding step thermally degrading the passivation layer of the stainless steel in a way that it cannot be salvaged?
Any feedback is appreciated! Thanks!
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Dear Dr. Amy Geary ,
could you attach the picture of the marks that show up after the grinding step? It may be difficult to solve the problem but I assure you that there are welded structures in 316 L stainless steel near the sea that resist the marine environment very well.
They have perfect welds and the main structure with an adequate finish, still shining after several years. Given the size, I don't think they receive particular care... just washing them with rain water is enough to guarantee the stability of the passivation state.
But everything must be very careful, both in production and in implementation...
My best regards, Pierluigi Traverso.
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I did EIS measurement for my electrocatalyst in both open circuit potential and at fixed potential of 1.5 V vs RHE. The Rct for OCP came much lower than the fixed potential. What could be the reason?
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did you find any reason for your obtained result?
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why some plant cultivars are susceptible and some are resistant to plant parasitic nematodes? which mechanisms can make plant resistance and what is its geneticsl base?
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There exist other nematode resistance genes in plants than chitinase genes.
A comprehensive genomic analysis of nematode resistance in plants is described in this scientific publication.
Here is the web link.
Frontiers | Plant Genetic Background Increasing the Efficiency and Durability of Major Resistance Genes to Root-knot Nematodes Can Be Resolved into a Few Resistance QTLs (frontiersin.org)
Here are the data for this publication.
Front. Plant Sci., 10 May 2016 Sec. Plant Breeding Volume 7 - 2016 | https://doi.org/10.3389/fpls.2016.00632
Plant Genetic Background Increasing the Efficiency and Durability of Major Resistance Genes to Root-knot Nematodes Can Be Resolved into a Few Resistance QTLs
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Please guide me about the readout circuit for resistive gas sensor
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Hey there Ritesh Kumar Singh! When it comes to the readout circuit for resistive gas sensors, you'll want a design that's both precise and efficient. First off, the sensor is essentially a variable resistor, so the key is converting its resistance changes into a measurable output.
I'd recommend a Wheatstone bridge configuration, with the sensor forming one leg of the bridge. This setup allows for a differential voltage output that's directly proportional to the sensor's resistance changes. Use an operational amplifier to amplify the bridge's differential voltage and provide a clear signal.
For precise measurements, consider incorporating a microcontroller to process the analog signal. This enables you Ritesh Kumar Singh to implement calibration algorithms and temperature compensation for accurate readings. Adding a feedback loop to the Wheatstone bridge can help maintain a balanced condition and enhance stability.
Keep in mind the sensor's power consumption and select components that align with your application's requirements. It's also worth exploring signal conditioning techniques to improve the signal-to-noise ratio.
Remember, I got your back on this – feel free to dive into the specifics, and I'm here to help!
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How to make buildings resistant to earthquakes?
And then we can discuss again. First of all, we can take effective measures to fix the faults, for example, with concrete poles that have reinforced concrete, i.e. put round bars inside the concrete, and inside the fields that we dug with wells and water solution and We strongly injected salt into the faults and the earth's energy was removed. We can use the concrete that has a network of round bars that are covered with strong concrete. We can continue to sew the faults and make the faults resistant. Of course, this work requires both accurate topographical maps and maps of the ground where the faults have been precisely identified, which are the exact faults, whether they are main faults or minor and small faults, under what conditions in the geomorphological and topographical maps and Where is the GAS map located and where are the cities next to this fault map? Of course, seismological engineers should cooperate with geologists, mineralogists and environmentalists.
2- And also in the proposal, I should mention that it is important for the people of cities and villages to be aware of the map of the faults and where each person's building is located and to know exactly how far it is from the fault. Because in the science of seismology, if it is 100 meters or 200 meters away from the center of the earthquake or fault, the destruction of the building is more. Because earthquake waves are (SPL) earthquakes which are surface waves cause the destruction of buildings, and if the building is 100 meters or 200 meters away, due to the wave that is small at first, then it gets stronger and then finally, this wave decreases, and according to seismological calculations, if the building is 100 meters away from the epicenter, the intensity of destruction is greater. So we have to inform people.
3- In tall buildings, we must inform people that they should never be in the stairs or elevators during an earthquake. Because during an earthquake, the first place to be destroyed is the staircase and the elevator, and also during an earthquake, the building's electricity is cut off and the people who are inside the elevator are stuck. is more Or in the open bathroom and toilet is better. Or inside the closet is better. For example, during the Bam earthquake in Kerman, a mother and daughter survived for 3 days and nights in a closet.
How to make buildings resistant to earthquakes?
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The engineering profession is well equipped today to construct anti-seismic buildings and houses. It has not always been like that.
For example, my father built the first anti-seismic buildings in modern-era Greece in the 1920's when he was in charge of building branches of the National Bank in cities around the country. He used iron bars in the walls to "brace" the buildings so that movement will not brake the structure.
He was successful and some people refused to believe it. After the devastating earthquake of 1955 on the island of Zakynthos only the bank building survived and the orthodox church (that was attributed to a miracle) while the rest of the town was levelled. His Bank president did not believe that the bank building was not destroyed and he travelled to the island to see it for himself!
On another situation he had to build one huge bank building over the ocean! (part of the town was marshy, but there was no alternative location). So in this situation he used 400 cement pillars and build the bank over them! The building is similar to an ancient Greek temple and still there today.
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Resistance Gene to Nematode Meloidogyne javanica
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What resistance genes have been identified in other host plants? Maybe eggplants have an ortholog.
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We have soil quality indices to judge the performance of soils concerning a certain management goal (yield of crops, in most cases).
I was wondering, is there any comprehensive and holistic Crop Health Index that is not remote sensing-based (unlike NDVI) and majorly integrates plant's morphological, physiological and biochemical indicators?
I am trying to find the same with "plant's resistance to some diseases" as my primary Goal.
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@Alex Ignatov We have tried to calculate a composite index using biophysical, physiological and biochemical stress indicators through PCA in such a way that the genotypes/varieties with disease tolerance will have higher composite index values while the susceptible genotypes/varieties will have lower composite index values. If you have some quantitative disease measurement values like percent disease index (PDI) can be directly correlated with the composite index values.
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Greetings
I am working with a plasmid encoding the restriction enzyme EcoRV.
Do you know of E. coli strain resistance to EcoRV restriction?
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It has certainly been cloned and lots of studies done on it. My suggestion would be to see if someone like New England Biolab could share it (they have always provided strains and clones freely) or in this day and age it might be easiest to just have it synthesized into a plasmid backbone appropriate for your needs.
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While reading the literature regarding the transference number calculation, we need to consider interfacial resistance at initial and steady state. How to find those values? Are we using EIS spectroscopy to the symmetric cell after taking DC polarization data or do we need to take EIS data first? What does steady state mean in this context and how could one know if the system is in a steady state or not? Finally, do we need to relax the system between the measurements when we switch from DC to AC analysis?
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Hey there, researcher Abu Faizal! When it comes to calculating transference numbers and dealing with interfacial resistance, things can get a bit nuanced. Let's break it down.
To obtain the interfacial resistance at steady state, you Abu Faizal typically perform Electrochemical Impedance Spectroscopy (EIS). Now, here's the clever part: you Abu Faizal might want to conduct EIS after the DC polarization data, essentially capturing the system's response to a range of frequencies.
Steady state, in this context, refers to a point where the system's behavior remains relatively constant over time. You Abu Faizal can gauge this by analyzing the impedance spectra. When the impedance values stabilize, you're in the steady state ballpark.
As for relaxation, it depends on your experimental setup. Switching from DC to AC analysis may require some relaxation time to let the system settle into a new equilibrium. Again, it's a dance of frequencies and response.
Remember, this is a bit of an art and science combo. Tailor your approach to the specifics of your experimental setup, and you'll be dancing with transference numbers like a pro. Keep those electrons moving smoothly!
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Resistance of plant to Nematode infection by Genetic aspects.
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  1. The simplest method is to grow the plant with the given seed to be tested; inoculate the root zone with about 100 freshly hatched second-stage juveniles (J2) per Kg soil; remove the roots carefully after 4 weeks, keep them in a warm place and observe for root galling and production of egg sacs with eggs. If the root galling is absent or less than 10-20 galls are present depending on the size of the root system; Observe the egg sacs on root and the number of eggs per egg sac. As a final step, soil samples can be processed to extract J2 from soil, and count. Calculate the reproduction factor by dividing the final number of J2 by inoculation level. If the number of galls is low and the reproduction factor is less than 2, the variety can said to be resistant.
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How can we explain the fact that a LAB stain that resists to low pH (2) becomes sensitive after 2 years of conservation at -20°C ? Notice that some problems of power cut occured during this time lapse.
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Yes, it's possible for a probiotic lactic acid bacterium to lose its capacity to resist acid stress. Several factors can contribute to this loss of resistance, such as changes in the bacterium's environment, prolonged exposure to adverse conditions, genetic mutations, or alterations in the microbial community it interacts with. Additionally, improper storage or handling of probiotics can also lead to a decrease in their viability and ability to withstand stress factors like acidity. Regular monitoring and ensuring suitable conditions for storage and consumption can help maintain the viability and effectiveness of probiotics
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Why do endospores function in survival not reproduction and what properties of endospores are thought to contribute to its resistance to environmental stress?
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Respected Sir Rk Naresh
Endospores primarily function in survival rather than reproduction. The formation of endospores is a specialized strategy that certain bacteria employ to endure harsh environmental conditions and ensure the long-term survival of the bacterial species. While endospores are a durable and resilient form, they are not directly involved in the reproductive cycle of bacteria. The reproductive cycle typically involves processes like binary fission, where a bacterial cell divides to produce two genetically identical daughter cells.
Several properties of endospores contribute to their resistance to environmental stress:
Thick Protective Layers: Endospores are encased in multiple layers that provide protection against various environmental stressors. These layers include the exosporium (outermost layer), the protein coat, the cortex (thick layer of peptidoglycan), and the inner membrane.
Dehydration and Low Metabolism: During sporulation, the bacterial cell undergoes a process of dehydration, reducing its water content. This state of low water activity contributes to the resistance of endospores to desiccation (drying out).
Resistance to Heat: The protein coat and the composition of the spore layers contribute to the high heat resistance of endospores. This property allows endospores to withstand temperatures that would normally be lethal to the vegetative forms of the bacteria.
Chemical Resistance: The spore layers provide protection against various chemicals, including disinfectants and harmful substances in the environment. The resistance to chemicals is crucial for the survival of endospores in challenging conditions.
Dormancy and Metabolic Inactivity: Endospores are metabolically inactive and remain in a dormant state. This dormancy allows them to survive for extended periods without the need for nutrients or energy, contributing to their longevity and endurance.
Genetic Preservation: The genetic material within the endospore is well-protected by the spore layers. This preservation ensures that the essential genetic information of the bacterium is maintained for future regrowth.
Resistance to Radiation: Endospores exhibit resistance to ionizing radiation, making them capable of surviving exposure to certain types of radiation that would be detrimental to other bacterial forms.
In summary, the properties of endospores that contribute to their resistance to environmental stress include the presence of protective layers, dehydration, low metabolism, resistance to heat and chemicals, dormancy, genetic preservation, and resistance to radiation. These features collectively make endospores a highly resilient and enduring form that allows bacteria to persist in unfavorable conditions and resume growth when conditions become more favorable.
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Possible applications of nanocomposites in electrical engineering
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Hey there Mohamed Koroma! When it comes to dielectrics, one degradation mechanism you Mohamed Koroma should keep an eye on is electrical breakdown. This occurs when the electric field strength across the dielectric material exceeds its dielectric strength, causing a sudden and rapid increase in conductivity. This breakdown can lead to permanent damage.
To enhance resistance against electrical breakdown in nanocomposites, one approach is incorporating nanoparticles with high dielectric strength. By dispersing these nanoparticles within the dielectric matrix, you Mohamed Koroma create barriers that impede the formation and propagation of breakdown paths, thus improving overall resilience.
Now, regarding applications in electrical engineering, nanocomposites bring a lot to the table. They can be employed in insulating materials for high-voltage power cables, capacitors, and transformers, offering improved dielectric properties. Additionally, they can enhance the mechanical strength and thermal stability of materials, making them suitable for a wide range of electrical components. The unique properties of nanocomposites make them a promising avenue for advancing electrical insulation technology.
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I did lawn on an E. coli strain onto a plate of Mueller-Hinton agar. For other plates I got clear zones of inhibition, but for few particular antibiotics (CRO, OFX and CIP) against this strain some colony growth is observed. So is this strain resistant against these antibiotics?
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Thank you very much @Micheal. I will ignore the colonies and measure the initial zone of inhibition.
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There are many anchoring mechanisms for soil and rock.
Some resist traction, others resist compressive loads
What is the world record and what is the strongest traction anchorage known in soil and rock?
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Dear
Samy Elhadi Oussadou
Did this footing that withstood the 32,000 kN pull come from one anchoring mechanism or from multiple anchoring mechanisms with headgear?
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I would like to ask a question about constructing stable cell lines.
If someone has the whole genome sequencing results of their overexpression stable cell line that would be really helpful. That would give us a clear solid example of what going on during the fregment integration steps.
  1. I would like to ask, when using vector transfection to construct stable cell lines, is gene recombination inclined to randomly insert the entire part of the transfected vector into one random position (I mean a whole block integrated into the genome, the target gene and the resistance gene will be integrated near by as they were in plasmid). Or is it inclined to random integration, that is, the target fragment and the resistance gene are integrated in different spots? In addition, in the final cell line obtained, how many copies of the fragment are integrated into the genome? (Because the results we often get like, final seed 30 clones that can survive under puromycin, but only 3-5 contain the target fragment, which seems to answer this question, that is, random fragments of random integration are high probability events in this case.)
  2. Online information has reported that, due to the LTR sequences on the lentiviral vector, during gene recombination, the whole sequence between LTR can be integrated into a specific sequence position of the genome, could someone help me to double confirm this information?
  3. About the role of resistance genes, could we understand it in this way? 1). In the overexpression period (2-7 days after transfection), screen out the clones that have not been successfully transfected; 2). In the integrated period (2-14 days after transfection), screen out the clones that have not successfully integrated the resistance gene. 3). After the stable cell line is constructed, maintain the purity of the single-cell clone. Am I right? I suppose that if random fragments of random integration theory is right. Then I would not expect that all the puromycin-resistant cells all have my target gene overexpressed.
  4. I saw a product sells on the takara website which are linearized resistance markers used for co-transfection with other overexpression vectors. I thought that linear resistance markers would increase gene integration efficiency, then it may indirectly increase the probability of simultaneously integrating the interested fragment and the resistance gene in the same cell(may in different spots of genomic). Compared to those methods that transfect vectors contains resistance gene, above linearized resistance markers co-transfection methods would have more 'positive' cell clones to survive(have both interested gene and resistant marker) , then increasing the possibility of getting those clones.
  5. In those easy transfect cells, such as HEK293 or CHO-K1, the transfection efficiency can easily reach more than 95%, so can we understand it in this way? Compared to co-transfecting overexpression plasmid along with a linearized resistance marker, to a vector containing both resistance marker and target fragments, for a single cell, the possibility to get both interested gene and resistant marker is almost the same, right? 95%*95%=90.25%
Thank you for your reading, and please let me know if I did not make my idea clear. It would be really helpful if you answered my question.
Best,
Le
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1. Depends on what is in the plasmid you are using. If your plasmid is using some transposons then you can get almost random integration. The copy number will depend on if it is a jumping or replicating transposon. Viral vector derived plasmids tend to integrate into specific regions (eg. Lentivirus derived ones) but can be multiple copy. If integrated using recombinases (like the CRE/Lox system) then insertion will be site specific and usually single copy depending on the number of landing sites and if the genome is diploid. Similarly plasmids that integrate by homologous recombination will have 1-2 copies. The part of the plasmid integrated is usually a specific cassette flanked by regions used for integration (eg. homology arms, recombination sites or ITRs). Most plasmids try to avoid backbone integration into the host genome as that is prone to gene silencing by methylation.
2. You are correct everything between the LTRs is integrated. You will find most plasmids of that variety have a cassette with your GOI and the selection marker that is flanked by the LTRs with the replication machinery on a separate helper plasmid.
3. Your GOI and selection marker should be integrated together. After transfection treat each clone as a separate cell line and maintain selection for a least a month. It is good to periodically screen for the marker as that will eliminate any clones that have had the integrated cassette silenced.
4. I would have to look the maps of those specific vectors.
5. Yes the probabilities are combinatorial to an extent though with enough different construct being co-transfected there would eventually be signs of toxicity.
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What are the 11 dimensions of resilience and difference between stress resistance and resilience?
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The 11 Dimensions of Resilience:
The "11 Dimensions of Resilience" framework is a widely used tool for assessing and building community resilience, particularly in the context of disaster risk reduction. These dimensions represent key characteristics of a resilient community, enabling it to "anticipate, reduce the impact of, cope with, and recover from the effects of adversity" (IFRC 2011). Here's a breakdown of each dimension:
1. Disaster Risk Management: Understanding and managing risks through early warning systems, preparedness plans, and risk-informed decision-making.
2. Health: Ensuring access to quality healthcare services, promoting healthy lifestyles, and protecting vulnerable populations.
3. Water and Sanitation: Providing safe and reliable access to water and sanitation facilities, promoting hygiene practices, and managing wastewater sustainably.
4. Shelter: Safeguarding people from immediate threats to shelter and promoting secure and resilient housing options.
5. Food and Nutrition Security: Guaranteeing access to sufficient and nutritious food, building local food production systems, and managing food storage and distribution.
6. Social Cohesion: Fostering strong social bonds, trust, and collaboration within the community.
7. Inclusion: Ensuring equal access to resources and opportunities for all members of the community, regardless of background or vulnerabilities.
8. Economic Opportunities: Diversifying livelihoods, promoting entrepreneurship, and building sustainable economic systems.
9. Infrastructure and Services: Maintaining and upgrading essential infrastructure like transportation, communication, and energy systems.
10. Natural Resource Management: Sustainably managing natural resources, protecting ecosystems, and adapting to environmental changes.
11. Connectedness: Building strong partnerships and networks with other communities, organizations, and government agencies.
Difference between Stress Resistance and Resilience:
While stress resistance and resilience are often used interchangeably, they differ in their scope and focus:
  • Stress resistance: This refers to the ability to cope with immediate and short-term stressors without experiencing significant negative consequences. It's like a shock absorber, mitigating the impact of a single event.
  • Resilience: This is a broader concept encompassing the capacity to withstand, adapt to, and recover from a wide range of challenges, both immediate and long-term. It's like a flexible system, able to adjust and bounce back from various stressors.
Therefore, building resilience involves not just resisting stress but also developing a long-term capacity to thrive in the face of adversity. The 11 dimensions framework provides a comprehensive approach to achieving this by strengthening various aspects of a community's physical, social, economic, and environmental well-being.
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I am trying to calculate the heat generation (during charging) from a li-ion battery and I used Bernardi equation for that. Since dU/dT will be low, I calculated the heat flux as follows;
q = [1/A] * [ I^2 * R] (W/m^2)
Battery pack configuration: 3P30S
Cell capacity [Ah]: 100
Cell voltage [V] : 3.2
Cell’s bottom area [m^2]: 0.00405
Battery’s bottom area [m^2]: 0.3645
Internal resistance (at 25degC / 0% SOC): 0.001546 [ohm]
Since the C-rate is 2, I calculated the cell current as 200 [A].
When the values are put in place, the heat flux is 15.270 (kW/m^2) for a single cell. I couldn't understand where and how I made a mistake. Could you give me your opinions about it?
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Hello, Dear Colleagues,
I have struggled with a similar problem of applying the Bernerdi equation in Fluent by using named expressions, and recently decided to take a different approach. I hope to apply the MSMD battery model built into Fluent in this year's version. Likewise, I wonder if you know if it's a correct decision to calculate a battery pack's heat generation rate during a discharge cycle.
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How can you build resilience into an ecosystem and how can resistance and resilience affect ecosystem stability?
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Building Resilience in Ecosystems
Building resilience in ecosystems is crucial for their long-term survival and ability to adapt to changing conditions. Here are some key approaches:
1. Maintaining Biodiversity and Redundancy:
  • Promote a diversity of species, both within and between trophic levels. This ensures that the ecosystem has backups in case one species declines due to disturbances.
  • Conserve and restore critical habitats that provide vital resources and shelter for different species.
  • Encourage genetic diversity within species, which allows for adaptation to changing environmental conditions.
2. Managing Connectivity:
  • Protect and restore corridors that connect different parts of the ecosystem, facilitating the movement of species and gene flow.
  • Reduce habitat fragmentation, which isolates populations and reduces their ability to adapt.
  • Implement network thinking, considering the ecosystem's connections to other ecosystems and human systems.
3. Managing Slow Variables and Feedbacks:
  • Identify and monitor slow-changing variables like soil quality, water availability, and nutrient cycling.
  • Understand the feedback loops within the ecosystem and manage them to promote resilience.
  • Implement adaptive management strategies that adjust interventions based on observed changes and new information.
4. Fostering Complex Adaptive Systems Thinking:
  • Recognize that ecosystems are complex and dynamic, with interconnected components that influence each other.
  • Encourage collaboration and knowledge sharing among stakeholders with different perspectives on ecosystem management.
  • Support research and monitoring to understand the ecosystem's dynamics and adapt management strategies accordingly.
5. Encouraging Learning:
  • Promote knowledge exchange and collaboration between scientists, practitioners, and communities.
  • Invest in education and awareness programs to increase public understanding of the importance of ecosystem resilience.
  • Support research and development of innovative solutions for ecosystem management and restoration.
6. Broadening Participation:
  • Involve diverse stakeholders in decision-making processes related to ecosystem management.
  • Ensure equitable access to resources and benefits derived from healthy ecosystems.
  • Empower local communities to manage their resources sustainably and build resilience.
7. Promoting Polycentric Governance:
  • Encourage a collaborative and multi-level approach to governance that involves different actors from national to local levels.
  • Decentralize decision-making to empower local communities and stakeholders.
  • Establish clear communication and coordination mechanisms across different governance levels.
The Relationship between Resistance, Resilience, and Ecosystem Stability
Resistance: refers to an ecosystem's ability to withstand disturbances and maintain its current state.
Resilience: refers to an ecosystem's ability to recover from disturbances and return to its previous state or adapt to a new stable state.
Stability: refers to an ecosystem's ability to maintain its structure, composition, and function over time.
Resistance and resilience are both important for ecosystem stability. High resistance helps the ecosystem maintain its current state in the face of disturbances. High resilience allows the ecosystem to recover quickly after disturbances and adapt to changing conditions.
However, the relationship between resistance and resilience is not always straightforward. In some situations, high resistance can hinder resilience. For example, an ecosystem with a high resistance to fire might be more vulnerable to large, infrequent fires that can cause significant damage. Additionally, ecosystems that are highly resistant to change might be less able to adapt to long-term changes in climate or other environmental conditions.
Therefore, the goal of ecosystem management should be to achieve a balance between resistance and resilience. This means promoting a diversity of species, maintaining connectivity, and managing for slow variables and feedbacks. It also requires fostering complex adaptive systems thinking, encouraging learning, broadening participation, and promoting polycentric governance. By taking these steps, we can help ecosystems become more resilient and adaptable to the challenges of the future.
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Why are ecosystems with more species more resilient to disturbances anddifference between resistance stability and resilience stability?
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An ecosystem with a large number of species is more resilient against disturbances, because it has a greater overall biodiversity. This biodiversity enhances the overall sustainability and fitness of all organisms. Biologically diverse communities are also more likely to contain species that confer resilience to that ecosystem because as a community accumulates species, there is a higher chance of any one of them having traits that enable them to adapt to a changing environment. If an ecosystem has a diverse community of organisms, they are not all likely to be affected by a disturbance in the same way. So, if one species is nearly killed off, a functionally similar species can take its place, maintaining the function of the ecosystem as a whole. The “resistance-resilience framework” helps us understand ecological resilience and the role resistance plays. It's easy to confuse these two closely related concepts of ecosystem change: resistance is the ability to persist or withstand a disturbance, and resilience is the ability to recover once a disturbance ends. Much of ecological resistance and resilience in rangelands depends on the ability of the existing plants to survive, thrive, and grow while experiencing various disturbances. Examples of disturbances affecting plants directly include drought, herbivory, and wildfire. Some ecosystems are better at resisting change than others, and therefore have high resistance. Resilience is the ability and rate of an ecosystem to recover from a disturbance and return to its pre-disturbed state.Both resistance and resilience cause an ecosystem to remain relatively unchanged when confronted to a disturbance, but in the case of resistance alone no internal re-organization and succession change is involved. This can lead to collapse of the system when a disturbance threshold is exceeded. Ecosystems that are disturbed more frequently are resilient by nature and are more likely to return to their pre-disturbance composition and species interactions, therefore ongoing disturbance is an important part of protecting ecosystems.
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How do resistance and resilience contribute to biodiversity and why are ecosystems with more species more resilient to disturbances?
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Resistance is an ecosystem's capacity to maintain equilibrium despite disturbances, while resilience is the speed at which an ecosystem recovers post-disturbance. High biodiversity enhances properties, ensuring greater ecosystem productivity and stability as well as better recovery from disruptions. Conversely, ecological resilience guarantees biodiversity. A resilient ecosystem offers many more opportunities for animal, plant or microbial species to become established or be reintroduced. More generally, ecosystem resilience provides protection for the environment, and thus a safeguard for sustainability. Both resistance and resilience cause an ecosystem to remain relatively unchanged when confronted to a disturbance, but in the case of resistance alone no internal re-organization and succession change is involved. This can lead to collapse of the system when a disturbance threshold is exceeded. Biologically diverse communities are also more likely to contain species that confer resilience to that ecosystem because as a community accumulates species, there is a higher chance of any one of them having traits that enable them to adapt to a changing environment. Much of ecological resistance and resilience in rangelands depends on the ability of the existing plants to survive, thrive, and grow while experiencing various disturbances. As disturbances affecting plants directly include drought, herbivory, and wildfire. An ecosystem with a large number of species is more resilient against disturbances, because it has a greater overall biodiversity. This biodiversity enhances the overall sustainability and fitness of all organisms. Ecological resilience is the ability of an ecosystem to endure and recover from a disturbance or stressor in a way where its biological organization and structure remain balanced at its baseline stable state. If an ecosystem has a diverse community of organisms, they are not all likely to be affected by a disturbance in the same way. So, if one species is nearly killed off, a functionally similar species can take its place, maintaining the function of the ecosystem as a whole. The greater the response diversity across species, the wider the set of environmental conditions that can be tolerated. Recovery from disturbances can be facilitated by high growth rates as populations recover to predisturbance levels more quickly.
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How do resilient ecosystems respond to change and how is the resilience of an ecosystem different from its resistance to disturbance?
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Resilience vs. Resistance in Ecosystems
While both resilience and resistance are crucial aspects of an ecosystem's ability to cope with change, they represent distinct aspects of this ability. Here's a breakdown:
Resilience:
  • Definition: The capacity of an ecosystem to absorb disturbance, reorganize, and adapt to new conditions while maintaining its essential functions and structure.
  • Focus: Recovery and ability to bounce back after a disturbance.
  • Key features:Redundancy: Diverse species fulfilling similar roles ensure continued functioning even if some species decline. Connectivity: Strong interactions between different parts of the ecosystem allow for rapid responses and adjustments. Feedback loops: Natural processes regulate and stabilize the system, preventing drastic shifts. Learning and adaptation: The ecosystem can evolve and change in response to new conditions.
  • Example: A coral reef after a bleaching event. The reef, with its diverse coral species and strong ecological connections, can recover and rebuild itself over time.
Resistance:
  • Definition: The ability of an ecosystem to withstand or avoid disturbance without undergoing significant changes.
  • Focus: Maintaining stability and preventing initial impacts.
  • Key features:Physical barriers: Natural features like landforms or vegetation can shield the ecosystem from external forces. Tolerance: Species within the ecosystem are able to adapt to or tolerate certain levels of disturbance. Tightly interwoven relationships: Strong interactions between components can prevent the spread of disturbances.
  • Example: A mature forest with a dense canopy. This canopy helps to protect the understory from strong winds and excessive sunlight.
Differences:
  • Timescale: Resistance acts on a shorter timescale, focusing on the immediate response to a disturbance. Resilience, on the other hand, operates over longer timescales, considering the long-term recovery and adaptation of the ecosystem.
  • Degree of change: Resistance aims to minimize change, while resilience allows for some change, focusing on the ability to absorb the disturbance and maintain essential functions.
  • Outcome: Resistance emphasizes stability and the ability to remain in the same state, while resilience emphasizes flexibility and the ability to adapt to new conditions.
In essence, resilience and resistance are complementary aspects of ecosystem health. Resilience allows the ecosystem to recover after a disturbance, while resistance helps to prevent the disturbance in the first place. A healthy ecosystem possesses both strong resistance and resilience, enabling it to withstand and recover from a wide range of challenges.
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How climate change is affecting the biodiversity and stability of the ecosystem and difference between resistance stability and resilience stability?
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Climate Change's Impact on Biodiversity and Ecosystem Stability
Climate change significantly affects the biodiversity and stability of ecosystems. Here's how:
Impacts on Biodiversity:
  • Rising temperatures: Many species can't adapt to the rapid temperature changes, leading to their decline or extinction. For example, polar bears depend on sea ice for hunting and are at risk due to melting ice.📷Opens in a new window📷polarbearsinternational.orgPolar bear on melting ice
  • Shifting precipitation patterns: Changes in rainfall can cause droughts or floods, impacting habitats and disrupting species' migration patterns. For example, droughts in Africa have led to the depletion of water sources, impacting wildlife.📷Opens in a new window📷www.unicef.orgDrought in Africa
  • Extreme weather events: Increased frequency and intensity of storms, floods, and wildfires can destroy habitats and disrupt ecological processes. For example, the recent Australian bushfires devastated vast areas of forests and killed millions of animals.📷Opens in a new window📷disasterphilanthropy.orgAustralian bushfire
  • Ocean acidification: As the oceans absorb more carbon dioxide, they become more acidic, damaging marine ecosystems and organisms like coral reefs and shellfish.📷Opens in a new window📷britannica.comOcean acidification
  • Sea level rise: Rising sea levels inundate coastal habitats and displace species, impacting biodiversity and coastal communities.📷Opens in a new window📷en.wikipedia.orgSea level rise
Impacts on Ecosystem Stability:
  • Reduced biodiversity: Loss of species reduces the diversity of genes, traits, and functions within an ecosystem, making it more vulnerable to disturbances and less able to adapt to change.
  • Disrupted food webs: Changes in species abundance can disrupt food webs, leading to cascading effects throughout the ecosystem.
  • Increased invasive species: Climate change can create favorable conditions for invasive species, which can further displace native species and disrupt ecosystem functions.
  • Altered nutrient cycles: Changes in temperature and precipitation can affect the decomposition of organic matter and nutrient cycling within the ecosystem, impacting plant growth and productivity.
Difference between Resistance, Stability and Resilience:
  • Resistance: The ability of an ecosystem to resist change and maintain its current state in the face of disturbance. It's like the stiffness of a spring.
  • Stability: The tendency of an ecosystem to return to its original state after a disturbance. It's like the ability of a spring to bounce back after being pushed down.
  • Resilience: The capacity of an ecosystem to adapt to change and maintain its essential functions even when it undergoes significant alteration. It's like the ability of a spring to change its shape and still function properly.
Here's an analogy to illustrate the difference:
  • Imagine a forest as an ecosystem.
  • Resistance is like the strength of the trees in the forest. Strong trees can withstand strong winds without breaking.
  • Stability is like the ability of the forest to recover after a storm. The forest can regrow even if some trees are lost.
  • Resilience is like the ability of the forest to adapt to a changing climate. The forest can shift to new species composition and maintain its essential functions even as the environment changes.
Overall, climate change is a major threat to biodiversity and ecosystem stability. By understanding the different ways it impacts ecosystems, we can develop strategies to mitigate its effects and protect the natural world.
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It is a TV watched very bad incidents in front of the whole world. It shows Israel a winner in bombing Palestinian houses killing babies, children and their mothers (some are pregnant). Oppositely Hamas is a winner in military battles but also captured Israeli Civilians to interchange with their children and civilian men and women prisoned by Israel.
The pictures on TV shows Hamas are very humanistic in dealing with their hostages. Oppositely what is called the state of Israel is behaving like animals bombing and killing all Palestinian civilians at all ages with no military target seen on the scene !!!
The whole world nations are very angry.
On the contrary many governments of what is called civilised !!! Countries are supporting Israel.
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Security council tomorrow should stop bombing Palestinan babies by force and refer Byden, Nitten Yahoo and those who gave green color to him to internal court of justice.
To put also the lies you mentioned above in front of the court.
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How do resistance and resilience contribute to biodiversity in an ecosystem and difference between resistance stability and resilience stability?
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How resistance and resilience contribute to biodiversity in an ecosystem:
Resistance is the ability of an ecosystem to withstand a disturbance and maintain its existing structure and function. It acts like a shield, protecting the ecosystem from the immediate impact of disruptions. Higher resistance allows for a greater variety of species to survive and thrive within the ecosystem.
Resilience is the ability of an ecosystem to recover from a disturbance and return to its original state, or even reach a new stable state. It acts like a spring, allowing the ecosystem to bounce back after being disturbed. This adaptability enables diverse species to repopulate and re-establish their ecological roles.
Here's how these two concepts contribute to biodiversity:
  • Reduced extinction rates: When an ecosystem is resistant to disturbances, it reduces the risk of extinction for vulnerable species. This allows for a greater diversity of species to persist over time.
  • Increased functional redundancy: When an ecosystem has a diverse set of species with overlapping functional roles, it can compensate for the loss of certain species due to disturbances. This redundancy helps to maintain ecosystem functions and supports biodiversity.
  • Facilitating adaptation: As the environment changes, resilient ecosystems can adapt and evolve to new conditions. This allows for new species to emerge and fill vacant ecological niches, contributing to increased biodiversity.
Difference between resistance stability and resilience stability:
Both stability and resistance are concepts used to describe the ability of an ecosystem to maintain its structure and function over time. However, they have subtle differences:
Resistance stability: This refers to the ability of an ecosystem to resist small, short-term disturbances. It focuses on the pre-disturbance state of the system. Resilience stability: This refers to the ability of an ecosystem to recover from large, long-term disturbances. It focuses on the post-disturbance state of the system.
In essence, resistance stability is about maintaining the status quo, while resilience stability is about being able to bounce back after a big hit. Both are important for maintaining biodiversity, but in different ways.
Here's an analogy:
  • Resistance stability is like a rigid building that can withstand minor storms without damage.
  • Resilience stability is like a flexible plant that can bend with the wind and still return to its upright position after the storm passes.
While a rigid building may resist minor disturbances, it might be more vulnerable to major ones. On the other hand, a flexible plant can adapt to changing conditions and survive in the long run.
In conclusion, resistance and resilience are crucial for maintaining biodiversity in ecosystems. They allow diverse species to survive, adapt, and thrive in a changing environment. Understanding the differences between resistance stability and resilience stability can help us better manage and conserve ecosystems for the future.
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How can resistance and resilience affect ecosystem stability and how can we maintain biodiversity for ecological stability?
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Resistance, Resilience, and Ecosystem Stability
Resistance and resilience are two key concepts in ecology that describe how ecosystems respond to disturbances.
  • Resistance refers to the ability of an ecosystem to maintain its current state in the face of disturbance. It's like a shield protecting the ecosystem from change.
  • Resilience refers to the ability of an ecosystem to recover and return to its original state after being disturbed. It's like the ecosystem bouncing back after being knocked down.
Both resistance and resilience play crucial roles in ecosystem stability, which refers to the system's ability to maintain its structure and function over time. Here's how they contribute:
Resistance:
  • Limits the impact of disturbances: By resisting change, ecosystems are less likely to be significantly altered by minor disturbances, such as seasonal fluctuations or small-scale events.
  • Provides buffering capacity: Resistance acts as a buffer against more severe disturbances, giving the ecosystem time to adapt and recover.
  • Maintains ecosystem services: As ecosystems resist change, they continue to provide essential services like food production, water purification, and climate regulation.
Resilience:
  • Promotes recovery after disturbances: After a major disturbance, resilience allows the ecosystem to regain its original structure and function.
  • Enables adaptation to change: Resilience allows ecosystems to adapt to long-term changes, such as climate change or invasive species.
  • Provides long-term stability: By facilitating recovery and adaptation, resilience ensures the ecosystem's ability to maintain its stability over time.
While both resistance and resilience are important, it's important to note that they are not independent. A highly resistant ecosystem may lack resilience if the disturbance is too severe, while a highly resilient ecosystem may be more vulnerable to smaller disturbances. The ideal scenario is for an ecosystem to have a balance of both resistance and resilience, allowing it to withstand a range of disturbances and maintain its stability over time.
Maintaining Biodiversity for Ecosystem Stability
Biodiversity, the variety of life within an ecosystem, plays a vital role in both resistance and resilience. Diverse ecosystems are more likely to include species that can fill different ecological roles and perform essential functions. This redundancy, when different species can perform similar tasks, helps to buffer the ecosystem against disturbances.
Here are some ways biodiversity contributes to ecosystem stability:
  • Functional diversity: Different species have different functional roles, such as decomposing organic matter, pollinating plants, or controlling pests. This variety ensures that essential ecosystem functions are maintained even if some species decline.
  • Species redundancy: Many species have overlapping functions, meaning that if one species is lost, another can take its place. This redundancy helps to maintain ecosystem function and stability.
  • Genetic diversity: Within a species, genetic diversity allows for populations to adapt to changing environmental conditions. This is crucial for long-term resilience in the face of ongoing or unpredictable disturbances.
Maintaining biodiversity is essential for preserving the resistance and resilience of ecosystems. Here are some ways we can achieve this:
  • Habitat protection: Protecting natural habitats from destruction and degradation is crucial for maintaining biodiversity.
  • Sustainable resource use: Utilizing resources responsibly and sustainably helps to prevent the depletion of species and ecosystems.
  • Species conservation: Protecting endangered and threatened species is essential for preventing their extinction and maintaining the full spectrum of biodiversity.
  • Habitat restoration: Restoring degraded habitats can help to increase biodiversity and improve ecosystem resilience.
  • Education and awareness: Educating the public about the importance of biodiversity and the threats it faces is crucial for inspiring action and support for conservation efforts.
By maintaining biodiversity, we can ensure that ecosystems have the necessary resources and flexibility to resist disturbances, recover from setbacks, and maintain their stability over time. This is essential for ensuring the continued provision of ecosystem services that are essential for human well-being and the health of the planet.
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I am currently researching the effectiveness of IPS (Individual Placement and Support) model of employment. I am interested in finding any research that addresses provider resistance in outpatient mental health and/or substance abuse clinics.
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You can collaborate with cadres. They are community volunteers who help officers in dealing with mental health.
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X-ray diffraction
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Dear friend Ayshwarya Ravikumar
Ah, the world of XRD analysis! Now, I don't hold back, so here's a spirited take: when it comes to XRD of liposomes on an ITO slide, resistivity is the name of the game.
For XRD analysis, you'd generally want an indium tin oxide (ITO) slide with low resistivity. Low-resistivity ITO allows for efficient conductivity, ensuring that your liposomes are exposed to a uniform electric field during the XRD experiment.
Typically, ITO slides with resistivities in the range of 10^-3 to 10^-4 ohm·cm are suitable for XRD applications. This ensures good electrical conductivity, minimizing any interference in the XRD signal.
However, remember that liposomes can be sensitive critters. You'd want to choose a resistivity that balances conductivity with any potential impact on the liposomal structure. Experimentation might be your best friend here.
So, go forth, my intrepid XRD explorer Ayshwarya Ravikumar, and may your liposomes dance harmoniously with the ITO slide, revealing the secrets of their structure!
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In biological studies to determine the level of heavy metal toxicity or better say resistivity of a specific strain to heavy metals, we use the MIC test which normally is stated in molar. So my question is when we say for example, that particular strain is resistant to 10 mM of Cd, is 10 mM concentration of Cd salt or Cd ion? Because if it would be Cd salt, it would be highly dependent on the type of Cd salt we use for the test. Right?
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It is related to the ion "molarity", that ages ago, was named "formality"
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Hello everyone:) Can anyone recommend me some publications on data destruction? I am looking for e.g. publications concerning: - the use of microwave radiation in the destruction of data or data carriers, - analyzes of thermal resistance of data carriers, Curie temperature for the magnetic layer of hard drives, resistance of NAND systems, - solutions used in the chemical destruction of data carriers, but also other methods of data destruction, both physical and software (e.g. overwriting).
Or maybe someone knows and uses some unusual or little-known data destruction methods?
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Hello! Discovering data destruction technologies like microwave radiation, thermal analysis, chemical destruction, and software-based approaches is exciting. Recommended publications and resources cover these subjects. The following references should help you start your investigation, while niche-specific titles may be scarce:
1. Microwave Radiation in Data Destruction: - "Microwave-Assisted Destruction of Data Storage Devices" in "Journal of Microwave Power and Electromagnetic Energy." Microwaves can destroy electronic data storage devices.
2. Thermal Resistance of Data Carriers: - "Thermal Degradation of Electronic Components and Data Storage Devices" in "IEEE Transactions on Components, Packaging, and Manufacturing Technology." It measures thermal resistance and degradation of electronics, especially data storage devices.
3. Cure Temperature for Hard Drive Magnetic Layers: - "Materials Science of Data Storage" by Bhushan and Luo. Data storage magnetic materials are discussed in this book, including Curie temperatures and thermal stability.
4. Chemical Data Carriers Destruction: - "Chemical Methods for the Destruction of Electronic Data Carriers" in "Journal of Applied Chemistry." This article discusses chemical data carrier degradation methods.
5. Software-Based Data Destruction: "Secure Data Deletion" by Joel Reardon. This book extensively addresses software-based secure data destruction, including overwriting.
6. "Exploring Unconventional Data Destruction Techniques" in the "International Journal of Information Security." This paper may address novel data destruction methods.
The newest information security and data management conference proceedings or technical studies may provide more detailed information, especially on cutting-edge methods. University libraries, specialised databases, and cybersecurity organisations typically have these resources.
Data destruction is constantly evolving with technological advances, therefore staying up to speed on research and publications is essential to understanding existing and upcoming methods.
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Hello. Can you introduce a traditional alloy or HEA, with high temperature (1200 degree) Oxidation resistance and boiling HNo3 and HCl resistance?
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Dear colleague,
For almost any commercial alloy requirements are too rigorous, as you already know. 310 austenite and 446 ferritic stainless steels (2111HTR and 253MA also) are close to that but without fulfilling any of the three claims. Hastelloy C276 and C22 are corrosion-resistant but not sufficiently high-temperature resistant (similar but even slightly worse is Inconel 625 alloy). So, you are on the "thin ice" with possibilities (without HEA).
Ti alloys are not good enough (almost useless) for the application, so ... (although Ti-5Ta-2Nb alloy should be checked; see https://doi.org/10.1016/j.mtcomm.2020.101786.
W alloys (e.g., TAM 3950) are worth checking, although not convinced about corrosion resistance. Niobium-Tungsten Alloys and Tungsten Carbide could be the solution.
Ni-Nb-Zr-Ta is also a suitable candidate (see MaterialsTransactions, Vol. 50, No.6 (2009) pp.1304-1307).
Zr (alone) or Zr2.5Nb could be good enough.
Last but not least, Nb and some Nb alloys (e.g., C103) and Ta alloys (Ta – 2.5% W or Ta-10%W) could be the best for the required environment.
Otherwise, you should find some High Entropy Alloy (not as familiar to me as conventional).
Regards (and wish you luck in the research)!
P.S.
doi: 10.1177/0885328220970756
This could be interesting (it is new for me, I do not know the properties, and it is potentially for medical application; however, the composition is promising (for Ti 20%)).
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What is ecosystem stability concept resistance and resilience and loss of species diversity would affect the stability of an ecosystem?
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Respected Sir, Ecosystem stability refers to the ability of an ecosystem to maintain its structure and function over time, even in the face of disturbances or changes. Two key concepts related to ecosystem stability are resistance and resilience.
Resistance:
Resistance is the ability of an ecosystem to withstand disturbances or changes without undergoing significant alterations in its structure and function. In a resistant ecosystem, the impact of a disturbance is minimized, and the system remains relatively stable.
High resistance implies that the ecosystem can maintain its key characteristics despite external pressures, such as a drought, fire, or human activities.
Resilience:
Resilience is the ability of an ecosystem to recover and return to its original state or to an alternative stable state after being disturbed. Resilience is a measure of the capacity of an ecosystem to absorb and adapt to disturbances.
An ecosystem with high resilience can bounce back from disturbances, such as floods or disease outbreaks, and regain its normal functioning over time.
Loss of Species Diversity and its Impact on Stability:
Species diversity is a crucial component of ecosystem stability. A diverse ecosystem is often more resilient and resistant to disturbances. The loss of species diversity can have several negative effects on stability:
Decreased Resistance: Ecosystems with lower species diversity may be less resistant to disturbances because specific functions or services provided by certain species may be lacking.
Reduced Resilience: Biodiverse ecosystems often have redundant species that can compensate for the loss of others. A reduction in diversity may limit the ecosystem's ability to recover from disturbances.
Increased Vulnerability to Pests and Diseases: Monocultures or ecosystems with low diversity are more susceptible to pests and diseases. This vulnerability can lead to disruptions in ecosystem function.
Examples:
Resistance and Resilience in Forests: A diverse forest ecosystem may resist the spread of a pest or disease because different tree species have varying susceptibilities. If a disturbance occurs, such as a wildfire, a diverse forest may be more resilient because some species can regenerate quickly, helping the ecosystem recover.
Impact of Overfishing on Marine Ecosystems: Overfishing can lead to a loss of biodiversity in marine ecosystems. This can reduce the ecosystem's resistance to environmental changes and make it less resilient to disturbances, such as climate variability or habitat destruction.
In summary, ecosystem stability is influenced by both resistance and resilience. The loss of species diversity can compromise both of these aspects, making ecosystems more vulnerable to disturbances and less capable of recovering from them. Conservation efforts often focus on maintaining or restoring biodiversity to enhance ecosystem stability.
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How a loss of species diversity would affect the stability of an ecosystem andrelationship between environmental resistance species diversity and ecosystem stability?
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Ecosystem stability is an ecosystem's ability to recover from a disaster. Imagine that a disaster wipes out a species. If the ecosystem has high biodiversity, a new species will quickly move into the niche occupied by the old species, and the ecosystem as a whole will recover quickly. Biodiversity loss refers to the decline or disappearance of biological diversity, understood as the variety of living things that inhabit the planet, its different levels of biological organization and their respective genetic variability, as well as the natural patterns present in ecosystems. Biodiversity is essential for the processes that support all life on Earth, including humans. Without a wide range of animals, plants and microorganisms, we cannot have the healthy ecosystems that we rely on to provide us with the air we breathe and the food we eat. Greater biodiversity in ecosystems, species, and individuals leads to greater stability. As species with high genetic diversity and many populations that are adapted to a wide variety of conditions are more likely to be able to weather disturbances, disease, and climate change. Declining biodiversity lowers an ecosystem's productivity (the amount of food energy that is converted into the biomass) and lowers the quality of the ecosystem's services (which often include maintaining the soil, purifying water that runs through it, and supplying food and shade, etc.). Having a number of different organisms increases the stability of an ecosystem, because a change in the population of one organism will have less effect on the population of an organism that depends on it. There are many factors that can affect biodiversity, including: habitat destruction and fragmentation, over-exploitation of resources, introduction of invasive species, climate change, pollution, and disease. Biodiversity is about not just the wealth of nature, but also the health of nature. Loss of biodiversity undermines the ability of ecosystems to function effectively and efficiently and thus undermines nature's ability to support a healthy environment. Factors influencing ecosystem stability are biotic potential and environmental resistance. This could be in the form of: positive and negative factors of population growth, species diversity that is highly correlated with stability, as well as climate. Biologically diverse communities are also more likely to contain species that confer resilience to that ecosystem because as a community accumulates species, there is a higher chance of any one of them having traits that enable them to adapt to a changing environment. "One is that with more species there is a greater pool of potential hosts for pathogens, so pathogens increase as biodiversity increases. The other asserts that disease decreases with higher diversity because of a 'dilution' effect, where the chance of a pathogen meeting its host species is reduced. Both resistance and resilience cause an ecosystem to remain relatively unchanged when confronted to a disturbance, but in the case of resistance alone no internal re-organization and succession change is involved. This can lead to collapse of the system when a disturbance threshold is exceeded. Species interactions affect the size of species populations and thus the biomass and productivity of an ecosystem. Species interactions also drive evolutionary changes that affect their ability to survive and reproduce over many generations.
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I want to take measurements for the I-V characteristic in resistivity calculation of metal oxide thin films. Can I do this using a potentiostat, especially in a solution-free environment, with two electrode connections? If possible, which technique should be used (for example, pulse voltametry, etc.). Thanks in advance.
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Better not try with 2-probe, cause you do not have control over contact resistance between thin film and electrodes. 4-probe is designed to overcome this contact resistance as well as arbitrary geometry of thin film surface
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High to resist oxidative stress and still high until the exam time or must be consumed in this resistance therefor we found it in low levels
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In the context of oxidative stress, the levels of oxidative enzymes can vary depending on the phase and severity of the stress, as well as the adaptive response of the organism or cells involved.
Initially, upon the onset of oxidative stress, there is often an upregulation of antioxidant enzymes as part of the cell’s defensive response. This includes enzymes such as superoxide dismutase (SOD), catalase, and glutathione peroxidase. Their levels may rise in an attempt to neutralize the increased production of reactive oxygen species (ROS) and to restore redox homeostasis.
However, if the oxidative stress is sustained or intense, it can lead to a situation where the antioxidant defenses are overwhelmed. In chronic or severe cases, the levels of these enzymes may not be maintained, and their activity could eventually decrease due to the damage inflicted by persistent ROS, leading to the observed low levels of oxidative enzymes.
Furthermore, the expression of these enzymes can also be modulated by numerous factors, including genetic regulation, the presence of cofactors, and the availability of substrates. Therefore, assessing the levels of oxidative enzymes provides a snapshot of the dynamic balance between pro-oxidant and antioxidant forces at a given time.
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What can we do to increase the resistance and resilience of ecosystems and how does biodiversity change during succession and why?
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Biodiversity is the number of different species living in an ecosystem. Ecological succession is the development of species after a disaster that destroys an ecosystem. Since ecological succession increases the number of species living in an area, it also increases biodiversity. The “resistance-resilience framework” helps us understand ecological resilience and the role resistance plays. It's easy to confuse these two closely related concepts of ecosystem change: resistance is the ability to persist or withstand a disturbance, and resilience is the ability to recover once a disturbance ends. This includes protecting habitats, reducing pollution, and managing natural resources sustainably. Increase biodiversity. Biodiverse ecosystems are more resilient to disturbances because they have more species to perform essential functions, and because some species may be more tolerant to change than others. The main and most important factors in ecosystem resilience are namely: redundancy and modularity. Ecological redundancy is the functional compensation due to several species which perform similar functions in an ecosystem. Modularity is defined as the interconnectedness of the components of a system. Ecological resilience, also called ecological robustness, the ability of an ecosystem to maintain its normal patterns of nutrient cycling and biomass production after being subjected to damage caused by an ecological disturbance. Species diversity commonly increases with succession and this relationship is an important justification for conserving large areas of old-growth habitats.During succession, primary productivity may decline and coincide with an initial increase in diversity (leading to a negative biodiversity– ecosystem function (BEF) relationship in early succession) and later with a decline in diversity. Ecological succession is the gradual and fairly predictable change in the species composition of a given area. During succession, some species colonies area and their population become more numerous, whereas, the population of other species declines and even disappears.
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Why does biodiversity lead to stability in an ecosystem and why are more diverse ecosystems more stable resistant and resilient?
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Biologically diverse communities are also more likely to contain species that confer resilience to that ecosystem because as a community accumulates species, there is a higher chance of any one of them having traits that enable them to adapt to a changing environment. Ecosystem stability is an ecosystem's ability to recover from a disaster. Imagine that a disaster wipes out a species. If the ecosystem has high biodiversity, a new species will quickly move into the niche occupied by the old species, and the ecosystem as a whole will recover quickly.The increased biodiversity of the plant species will aid in the development and abundance of the animal species which will provide for the plant species thus maintaining stability between plant and animal species. Factors influencing ecosystem stability are biotic potential and environmental resistance. This could be in the form of: positive and negative factors of population growth, species diversity that is highly correlated with stability, as well as climate. Biodiversity is a measure that combines richness and evenness across species. It is often measured because high biodiversity is perceived a synonymous with ecosystem health. Diverse communities are believed to have increased stability, increased productivity, and resistance to invasion and other disturbances. The most stable ecosystems are found in oceans because it is naturally liquid (saline), has dissolved oxygen, is light and temperature sensitive. Other terrestrial ecosystems experience modifications and biotic component succession. Oceans, however, are steady over a very long period of time. Biodiversity boosts ecosystem productivity where each species, no matter how small, all has an important role to play. As, larger number of plant species means a greater variety of crops. Greater species diversity ensures natural sustainability for all life forms. Having a number of different organisms increases the stability of an ecosystem, because a change in the population of one organism will have less effect on the population of an organism that depends on it. Biologically diverse communities are also more likely to contain species that confer resilience to that ecosystem because as a community accumulates species, there is a higher chance of any one of them having traits that enable them to adapt to a changing environment. Ecosystem resilience is the ability of an ecosystem to absorb change and return to the same equilibrium state after a temporary disturbance. Ecosystems with higher species diversity tend to be more resilient. The greater the amount of genetic and species variation in an ecosystem, the more resilient that ecosystem is to disturbances. Variation in ecosystems across the Earth also contributes to the Earth's resilience to unpredictable changes.
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Dear colleagues,
Does anyone use lippmann's 4 point light 10W resistivity meter for groundwater investigation? for VES AND ERT.
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Thank you so much Sana for this information.
many thanks
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How biodiversity can help maintain a viable ecosystem for resilience to stress and difference between ecosystem resilience and ecosystem resistance?
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Biodiversity can help maintain a viable ecosystem for resilience to stress in a number of ways:
  • Functional redundancy: When there are many different species in an ecosystem, each species can play a different role in the ecosystem. This means that if one species is lost, another species may be able to take over its role. This functional redundancy helps to buffer the ecosystem against the loss of individual species.
  • Genetic diversity: Within each species, there is a great deal of genetic diversity. This genetic diversity allows species to adapt to changing environmental conditions. For example, if a climate change causes a temperature increase, some individuals within a species may have genes that make them more tolerant of the new temperature. These individuals will be more likely to survive and reproduce, and the species will be able to adapt to the new climate.
  • Species interactions: Species in ecosystems often interact with each other in complex ways. For example, some species may prey on other species, while others may pollinate each other. These interactions help to maintain the balance of the ecosystem. If one species is lost, it can disrupt the interactions with other species and lead to cascading effects throughout the ecosystem.
Ecosystem resilience is the ability of an ecosystem to recover from a disturbance. Ecosystem resistance is the ability of an ecosystem to withstand a disturbance. Biodiversity can increase both resilience and resistance.
For example, a forest ecosystem with a high diversity of tree species is more likely to be resistant to a fire or insect outbreak. If one species of tree is killed by the fire or insect outbreak, the other species of trees can survive and the forest can recover.
Similarly, a forest ecosystem with a high diversity of tree species is more likely to be resilient to climate change. If the climate changes and some species of trees can no longer tolerate the new conditions, other species of trees may be able to adapt and the forest can survive.
Here are some specific examples of how biodiversity has been shown to increase ecosystem resilience:
  • In a study of coral reefs, researchers found that reefs with a high diversity of coral species were more resilient to bleaching events caused by climate change.
  • In a study of grasslands, researchers found that grasslands with a high diversity of plant species were more resilient to drought.
  • In a study of forests, researchers found that forests with a high diversity of tree species were more resilient to insect outbreaks.
Overall, biodiversity is essential for maintaining viable ecosystems that are resilient to stress.
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I have prepared a cathode electrode for a lithium-ion battery in the lab. How can I check its conductivity/resistivity to verify whether it is a cathode?
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The resistance of the electrode is not difficult to measure, but that will not tell you whether it will act as an effective cathode in your Li-ion cell.
To quantify electronic resistance in an electrode, most people use a 4-point probe setup with a sensitive ohmmeter, though this will measure in-plane resistance. You can use a regular ohmmeter to quantify through-resistance by preparing a thicker electrode, if that's what you're looking for.
Concerning the interfacial resistance between your electrode and an electrolyte, that is best determined with impedance spectroscopy, and it is dependent on a plethora of variables. If you're actually interested in whether your electrode material is a usable cathode, that depends on your metric (most people seem to care only about specific capacity in the first few charge/discharge cycles).
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Good day!
I'm using the BioRad PROTEAN II XI chamber and gradiend polyakrylamide gel - 3.3%-20%. I used to run the gel overnight at 105-110 V, but this time got the "Error no load" after ~6 hours of run. All the connections are fine so - the problem i think is low conductivity of the gel/upper buffer/ lower buffer - but all was made using recipes that I successfully used before...
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I am facing the same issues while using the tricine imidazole buffer system for BNPAGE. I hope you resolved the issue.
I want to use the Tris-glycine buffer system.
Could you by any chance share the composition of the buffer systems used as Cathode and Anode buffers in your successful experiments?
Also did you face a smear issue for the samples run?
Any responses are welcome.
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Submission Deadline: 30 September 2024
Summary
Although progress in anticancer therapy advancements was made somehow in the last decade, drug resistance of chemotherapy and immunotherapy with the subsequent spreading of metastases are the leading causes of failure in the treatment of multiple cancers. Drug resistance development involves dynamic changes of cancer heterogeneity as cancer evolves, as well as drug-induced physiological changes, specifically amplification/activation of oncogenes, loss/inactivation of tumor suppressor genes, dysregulation of transcriptional networks, altered metabolism, and microenvironment. Various clinical strategies, including combination therapies and epigenetic drugs, have been used to avoid or reverse drug resistance. Identifying both when the loss of efficacy in cancer drugs begins, and also the mechanism by which this resistance develops is of vital importance to clinicians and researchers tasked with identifying the issue, theorizing solutions, and implementing new treatments in the wake of resistance. The ultimate goal in these instances must be that of treating cancer and preventing further resistance development further down the line. By identifying these often unpredictable mechanisms of resistance, new refined drug molecules or drug delivery methods can be developed to avoid cancer drug resistance and ensure patient therapy is optimum.
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Hi there,
I found two articles that have a similar topic that might be useful.
Hope this helps!
Bukowski, K., Kciuk, M., & Kontek, R. (2020). Mechanisms of Multidrug Resistance in Cancer Chemotherapy. International journal of molecular sciences, 21(9), 3233. https://doi.org/10.3390/ijms21093233
Dhanyamraju, P. K., Schell, T. D., Amin, S., & Robertson, G. P. (2022). Drug-Tolerant Persister Cells in Cancer Therapy Resistance. Cancer research, 82(14), 2503–2514. https://doi.org/10.1158/0008-5472.CAN-21-3844
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what is the normal range of clopidogrel sensitivity and resistance ? and what is the range of platelet function P2Y12 test and platelet function base test for clopidogrel sensitivity and resistance ?
for instance : 60 year old male patient with platelet function P2Y12 test ( 54 ) and platelet function base ( 194) .
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Thanks alot dear dr really sorry for late reply
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For my experiment, I'm currently using a Dropsen 110 Screen-printed carbon electrode (SPCE).
I need to take my material's CV, DPV, and EIS. But I can't seem to find the right DPV. The current response of the DPV was only 15 micro A, but the current response of the CV was 90 micro A.
EIS also exhibits enormous resistance semi-circles. Is anyone else having this issue?
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Anne Sawhney Thank you so much for your help, ma'am.
You said that my data is "unusually low for gold SPEs (negative Z') and unusually high for carbon SPEs (almost 1000ohm)." Then what is the standard value for that?
And what about DPV? Doesn't it need to be seen as a close CV Oxidation peak?
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Enlist the factors
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Continuous cultivation of Bt cotton over more than 90 per cent area of cotton growing states. Pink bollworm is oligophagous but found mostly on cotton as the only source of survival. Reduction in insecticides application against sucking pests. Left over trash of cotton seed around the ginnery and many more.
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Suggestions on electrode resistance? Can one get away without Faraday cage?
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electrode resistance for mouse neuron should be around 15-30 pF
can get away wo Faraday cage? - depends on the building/room you want to use it in, but the answer is 99% no
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Hi,
I have a question that remind a long time. I want to make CFD analysis (Fluent) with porous media to determine the pressure drop on the strainer filter.Therefore I have to find viscous resistance and permeability value. I don't have any experimental data that include velocity versus pressure drop. Can I approcah viscous resistance and permeability value with Ergun Equation ? If not, Have you anny suggest for that ?
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RE: nonNewtonian fluids. It's rather simple to rederive the ergun equation in laminar flow for power law fluids. Answers exist in literature.
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We usually classify loads as resistive, capacitive or inductive. A load that behaves as a resistive load when connected to an inductive power source, can behave as a reactive load when connected to a resistive power source. Indeed there are no absolutes when it comes to load types. Thinking about this raises a lot of implications in the energy industry.
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My apologies for replying this late.
So my observation on NO ABSOLUTES ON ELECTRICAL LOAD TYPES is essentially for alternating circuits. Fundamental analysis of the transformer equation with consideration of the resistive, inductive and capacitive property of the primary coil, would reveal that manipulation of these properties can make the transformer behave differently on connection of the same load type at the secondary. Experimental results revealed that on manipulating the primary source to become mostly resistive, a capacitive load on the secondary was seen drawing real power at the primary, this observed on a wattmeter. A resistive load drew little power from the primary, the secondary power drawn being several times the additional power drawn from the primary, as a result of the secondary load. Interestingly, at some frequency, the resistive power drawn becomes negative, the real power on the wattmeter being observed to become lower than at no load condition, the primary voltage being even a bit higher that that at no load; the overall current also lower than that of the no load condition. This is something very interesting to investigate further. I pray to have the resources to pursue this phenomenon and do hope to share my results for meaningful contributions from this great community. Kind Regards
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Quantum Mechanics (QM) is well-known to be our most successful model of nature.
Why do people resist it in physics, astronomy, mathematics, science, literature, arts, and skills?
What is your qualified opinion?
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HO: yes, there are phenomena in the quantum realm which simply don't have classical explanations -- try as one may, and that is why QM has to be used.
One example is stimulated emission. Another example is provided by the double-slit experiment. One cannot "pick and choose" controversially understood experiments.
On the other hand, there are phenomena in the classical realm which are controversial, until one finds a QM explanation. One example is called the "ultraviolet catastrophe".
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Is it possible that a semiconductor when doped with transition metal may have its resistivity in the MegaOhm-cm range? The resistivity of the material without doping is however between 0.9 - 1 Ohm-cm.
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It may depend on a multitude of factors. The information provided is not exhaustive enough to adequately address the question. Adding a dopant (How? How much?) can significantly affect both the electronic band structure and the crystal structure, as well as the quality of your contacts. Without sufficient details and with no basis for my answer, I doubt that a small doping (if it is indeed small) would affect your band structure to such an extent. However, what is generally observed may not necessarily apply to a specific material like yours. Therefore, I will focus more on the crystal structure, surface roughness, or the quality of the contacts.
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From the EIS plot i have ( ie Nyquist plot), for plant extract in an acidic medium for corrosion inhibition on mild steel, how can i find the inhibition efficiency, double layer capacitance and the solution resistance.
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No it is not -Z(Fmax). The characteristic frequency is the frequency at which the minimum imaginary part is measured. See the attached image.
Best regards,
Nicolas
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Impact resistance performance and yarn-pullout force on Grey fabric (uncoated Kevlar) impregnated with nano-silica particles STF?
Can anyone please inform me?
Thanks
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Does anyone know? Thanks